Role of epigenetics in human aging and longevity: genome-wide DNA methylation profile in centenarians and centenarians’ offspring D Gentilini, D Mari, D Castaldi, D Remondini, G Ogliari, R Ostan, L Bucci, ... Age 35, 1961-1973, 2013 | 247 | 2013 |
Evidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor β2 promoter in breast cancer cells SM Sirchia, AT Ferguson, E Sironi, S Subramanyan, R Orlandi, ... Oncogene 19 (12), 1556-1563, 2000 | 244 | 2000 |
Endogenous reactivation of the RARβ2 tumor suppressor gene epigenetically silenced in breast cancer SM Sirchia, M Ren, R Pili, E Sironi, G Somenzi, R Ghidoni, S Toma, ... Cancer research 62 (9), 2455-2461, 2002 | 205 | 2002 |
Epigenetic modulation of the IGF2/H19 imprinted domain in human embryonic and extra-embryonic compartments and its possible role in fetal growth restriction S Tabano, P Colapietro, I Cetin, FR Grati, S Zanutto, C Mandò, ... Epigenetics 5 (4), 313-324, 2010 | 165 | 2010 |
Preferential X chromosome loss but random inactivation characterize primary biliary cirrhosis M Miozzo, C Selmi, B Gentilin, FR Grati, S Sirchia, S Oertelt, M Zuin, ... Hepatology 46 (2), 456-462, 2007 | 151 | 2007 |
Loss of the inactive X chromosome and replication of the active X in BRCA1-defective and wild-type breast cancer cells SM Sirchia, L Ramoscelli, FR Grati, F Barbera, D Coradini, F Rossella, ... Cancer research 65 (6), 2139-2146, 2005 | 119 | 2005 |
Misbehaviour of XIST RNA in breast cancer cells SM Sirchia, S Tabano, L Monti, MP Recalcati, M Gariboldi, FR Grati, ... PloS one 4 (5), e5559, 2009 | 98 | 2009 |
Genome‐wide analysis of primary plasma cell leukemia identifies recurrent imbalances associated with changes in transcriptional profiles L Mosca, P Musto, K Todoerti, M Barbieri, L Agnelli, S Fabris, G Tuana, ... American journal of hematology 88 (1), 16-23, 2013 | 89 | 2013 |
Increased loss of the Y chromosome in peripheral blood cells in male patients with autoimmune thyroiditis L Persani, M Bonomi, A Lleo, S Pasini, F Civardi, I Bianchi, I Campi, ... Journal of autoimmunity 38 (2-3), J193-J196, 2012 | 88 | 2012 |
Blood fetal microchimerism in primary biliary cirrhosis P Invernizzi, C De Andreis, SM Sirchia, PM Battezzati, M Zuin, F Rossella, ... Clinical & Experimental Immunology 122 (3), 418-422, 2000 | 87 | 2000 |
A multi-method approach to the molecular diagnosis of overt and borderline 11p15. 5 defects underlying Silver–Russell and Beckwith–Wiedemann syndromes S Russo, L Calzari, A Mussa, E Mainini, M Cassina, S Di Candia, ... Clinical epigenetics 8, 1-15, 2016 | 71 | 2016 |
Confined placental mosaicism G Simoni, SM Sirchia Prenatal diagnosis 14 (13), 1185-1189, 1994 | 57 | 1994 |
Microtubule-associated protein/microtubule affinity-regulating kinase 4 (MARK4) plays a role in cell cycle progression and cytoskeletal dynamics D Rovina, L Fontana, L Monti, C Novielli, N Panini, SM Sirchia, E Erba, ... European journal of cell biology 93 (8-9), 355-365, 2014 | 44 | 2014 |
OTX1 expression in breast cancer is regulated by p53 A Terrinoni, IS Pagani, I Zucchi, AM Chiaravalli, V Serra, F Rovera, ... Oncogene 30 (27), 3096-3103, 2011 | 44 | 2011 |
Quantitative DNA methylation analysis improves epigenotype-phenotype correlations in Beckwith-Wiedemann syndrome M Calvello, S Tabano, P Colapietro, S Maitz, A Pansa, C Augello, ... Epigenetics 8 (10), 1053-1060, 2013 | 43 | 2013 |
Preferential expression of mutant ABCD1 allele is common in adrenoleukodystrophy female carriers but unrelated to clinical symptoms E Salsano, S Tabano, SM Sirchia, P Colapietro, B Castellotti, C Gellera, ... Orphanet journal of rare diseases 7, 1-9, 2012 | 43 | 2012 |
Loss of heterozygosity on chromosome 4q32–35 in sporadic basal cell carcinomas: evidence for the involvement of p33ING2/ING1L and SAP30 genes E Sironi, A Cerri, D Tomasini, SM Sirchia, G Porta, F Rossella, FR Grati, ... Journal of cutaneous pathology 31 (4), 318-322, 2004 | 41 | 2004 |
The methylation of the TSC2 promoter underlies the abnormal growth of TSC2 angiomyolipoma-derived smooth muscle cells E Lesma, SM Sirchia, S Ancona, S Carelli, S Bosari, F Ghelma, ... The American journal of pathology 174 (6), 2150-2159, 2009 | 40 | 2009 |
Epigenetic alterations in cancer and personalized cancer treatment M Miozzo, V Vaira, SM Sirchia Future oncology 11 (2), 333-348, 2015 | 39 | 2015 |
ESX1 gene expression as a robust marker of residual spermatogenesis in azoospermic men E Bonaparte, M Moretti, GM Colpi, F Nerva, G Contalbi, L Vaccalluzzo, ... Human Reproduction 25 (6), 1398-1403, 2010 | 36 | 2010 |