c-Jun N-terminal kinase (JNK) signaling: recent advances and challenges MA Bogoyevitch, KRW Ngoei, TT Zhao, YYC Yeap, DCH Ng Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (3), 463-475, 2010 | 436 | 2010 |
mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress NXY Ling, A Kaczmarek, A Hoque, E Davie, KRW Ngoei, KR Morrison, ... Nature metabolism 2 (1), 41-49, 2020 | 134 | 2020 |
AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965 TA Dite, CG Langendorf, A Hoque, S Galic, RJ Rebello, AJ Ovens, ... Journal of Biological Chemistry 293 (23), 8874-8885, 2018 | 126 | 2018 |
Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms SL Pinkosky, JW Scott, EM Desjardins, BK Smith, EA Day, RJ Ford, ... Nature metabolism 2 (9), 873-881, 2020 | 105 | 2020 |
WD40-repeat protein 62 is a JNK-phosphorylated spindle pole protein required for spindle maintenance and timely mitotic progression MA Bogoyevitch, YYC Yeap, Z Qu, KR Ngoei, YY Yip, TT Zhao, JI Heng, ... Journal of cell science 125 (21), 5096-5109, 2012 | 92 | 2012 |
The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs TA Dite, NXY Ling, JW Scott, A Hoque, S Galic, BL Parker, KRW Ngoei, ... Nature Communications 8 (1), 571, 2017 | 77 | 2017 |
Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding CG Langendorf, KRW Ngoei, JW Scott, NXY Ling, SMA Issa, MA Gorman, ... Nature communications 7 (1), 10912, 2016 | 75 | 2016 |
Immortalized Parkinson's disease lymphocytes have enhanced mitochondrial respiratory activity SJ Annesley, ST Lay, SW De Piazza, O Sanislav, E Hammersley, ... Disease models & mechanisms 9 (11), 1295-1305, 2016 | 59 | 2016 |
The myokine meteorin‐like (metrnl) improves glucose tolerance in both skeletal muscle cells and mice by targeting AMPKα2 JO Lee, WS Byun, MJ Kang, JA Han, J Moon, MJ Shin, HJ Lee, JH Chung, ... The FEBS Journal 287 (10), 2087-2104, 2020 | 55 | 2020 |
Structural determinants for small-molecule activation of skeletal muscle AMPK α2β2γ1 by the glucose importagog SC4 KRW Ngoei, CG Langendorf, NXY Ling, A Hoque, S Varghese, ... Cell chemical biology 25 (6), 728-737. e9, 2018 | 50 | 2018 |
c-Jun N-terminal kinase phosphorylation of stathmin confers protection against cellular stress DCH Ng, TT Zhao, YYC Yeap, KR Ngoei, MA Bogoyevitch Journal of Biological Chemistry 285 (37), 29001-29013, 2010 | 46 | 2010 |
DNA-dependent protein kinase regulates lysosomal AMP-dependent protein kinase activation and autophagy P Puustinen, A Keldsbo, E Corcelle-Termeau, K Ngoei, SL Sønder, ... Autophagy 16 (10), 1871-1888, 2020 | 41 | 2020 |
CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins CG Langendorf, MT O'Brien, KRW Ngoei, LM McAloon, U Dhagat, ... Journal of Biological Chemistry 295 (48), 16239-16250, 2020 | 34 | 2020 |
Characterization of a novel JNK (c-Jun N-terminal kinase) inhibitory peptide KRW Ngoei, B Catimel, N Church, DS Lio, C Dogovski, MA Perugini, ... Biochemical Journal 434 (3), 399-413, 2011 | 30 | 2011 |
ATP synthase inhibitory factor 1 (IF1), a novel myokine, regulates glucose metabolism by AMPK and Akt dual pathways HJ Lee, J Moon, IH Chung, JH Chung, C Park, JO Lee, JA Han, MJ Kang, ... The FASEB Journal 33 (12), 14825-14840, 2019 | 25 | 2019 |
A novel retro-inverso peptide is a preferential JNK substrate-competitive inhibitor KRW Ngoei, B Catimel, N Milech, PM Watt, MA Bogoyevitch The International Journal of Biochemistry & Cell Biology 45 (8), 1939-1950, 2013 | 15 | 2013 |
Intracellular mobility and nuclear trafficking of the stress-activated kinase JNK1 are impeded by hyperosmotic stress M Misheva, G Kaur, KRW Ngoei, YY Yeap, IHW Ng, KM Wagstaff, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1843 (2), 253-264, 2014 | 14 | 2014 |
Identification and characterization of bi-thiazole-2, 2′-diamines as kinase inhibitory scaffolds KRW Ngoei, DCH Ng, PR Gooley, DP Fairlie, MJ Stoermer, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (6), 1077-1088, 2013 | 14 | 2013 |
An AMPKα2-specific phospho-switch controls lysosomal targeting for activation KR Morrison, WJ Smiles, NXY Ling, A Hoque, G Shea, KRW Ngoei, D Yu, ... Cell reports 38 (7), 2022 | 13 | 2022 |
The Spectrum of Neurological and White Matter Changes and Premutation Status Categories of Older Male Carriers of the FMR1 Alleles Are Linked to Genetic … DZ Loesch, N Trost, MQ Bui, E Hammersley, ST Lay, SJ Annesley, ... Frontiers in genetics 9, 531, 2018 | 11 | 2018 |