Unexpected Bacterial Origin of the Antibiotic Icosalide: Two-Tailed Depsipeptide Assembly in Multifarious Burkholderia Symbionts B Dose, SP Niehs, K Scherlach, LV Flórez, M Kaltenpoth, C Hertweck ACS chemical biology 13 (9), 2414-2420, 2018 | 69 | 2018 |
Highly parallelized droplet cultivation and prioritization of antibiotic producers from natural microbial communities L Mahler, SP Niehs, K Martin, T Weber, K Scherlach, C Hertweck, M Roth, ... Elife 10, e64774, 2021 | 56 | 2021 |
Bacterial endosymbionts protect beneficial soil fungus from nematode attack H Büttner, SP Niehs, K Vandelannoote, Z Cseresnyés, B Dose, I Richter, ... Proceedings of the National Academy of Sciences 118 (37), e2110669118, 2021 | 52 | 2021 |
Insect‐associated bacteria assemble the antifungal butenolide gladiofungin by non‐canonical polyketide chain termination SP Niehs, J Kumpfmüller, B Dose, RF Little, K Ishida, LV Flórez, ... Angewandte Chemie International Edition 59 (51), 23122-23126, 2020 | 36 | 2020 |
Genomics-driven discovery of a linear lipopeptide promoting host colonization by endofungal bacteria SP Niehs, K Scherlach, C Hertweck Organic & Biomolecular Chemistry 16 (37), 8345-8352, 2018 | 35 | 2018 |
Genomics‐driven discovery of a symbiont‐specific cyclopeptide from bacteria residing in the rice seedling blight fungus SP Niehs, B Dose, K Scherlach, M Roth, C Hertweck ChemBioChem 19 (20), 2167-2172, 2018 | 28 | 2018 |
Bacterial ectosymbionts in cuticular organs chemically protect a beetle during molting stages RS Janke, F Kaftan, SP Niehs, K Scherlach, A Rodrigues, A Svatoš, ... The ISME Journal 16 (12), 2691-2701, 2022 | 26 | 2022 |
Differential effects of Helenalin, an anti-inflammatory sesquiterpene lactone, on the proteome, metabolome and the oxidative stress response in several immune cell types P Zwicker, N Schultze, S Niehs, D Albrecht, K Methling, M Wurster, ... Toxicology in Vitro 40, 45-54, 2017 | 24 | 2017 |
Genome mining reveals endopyrroles from a nonribosomal peptide assembly line triggered in fungal–bacterial symbiosis SP Niehs, B Dose, K Scherlach, SJ Pidot, TP Stinear, C Hertweck ACS Chemical Biology 14 (8), 1811-1818, 2019 | 22 | 2019 |
Mining symbionts of a spider‐transmitted fungus illuminates uncharted biosynthetic pathways to cytotoxic benzolactones SP Niehs, B Dose, S Richter, SJ Pidot, HM Dahse, TP Stinear, C Hertweck Angewandte Chemie International Edition 59 (20), 7766-7771, 2020 | 20 | 2020 |
Biosynthesis of Sinapigladioside, an Antifungal Isothiocyanate from Burkholderia Symbionts B Dose, SP Niehs, K Scherlach, S Shahda, LV Flórez, M Kaltenpoth, ... ChemBioChem 22 (11), 1920-1924, 2021 | 19 | 2021 |
Toxin-producing endosymbionts shield pathogenic fungus against micropredators I Richter, S Radosa, Z Cseresnyés, I Ferling, H Büttner, SP Niehs, R Gerst, ... MBio 13 (5), e01440-22, 2022 | 15 | 2022 |
Multimodal molecular imaging and identification of bacterial toxins causing mushroom soft rot and cavity disease B Dose, T Thongkongkaew, D Zopf, HJ Kim, EV Bratovanov, ... ChemBioChem 22 (19), 2901-2907, 2021 | 12 | 2021 |
A highly conserved gene locus in endofungal bacteria codes for the biosynthesis of symbiosis-specific cyclopeptides SP Niehs, K Scherlach, B Dose, Z Uzum, TP Stinear, SJ Pidot, C Hertweck PNAS nexus 1 (4), pgac152, 2022 | 10 | 2022 |
Food‐Poisoning Bacteria Employ a Citrate Synthase and a Type II NRPS To Synthesize Bolaamphiphilic Lipopeptide Antibiotics B Dose, C Ross, SP Niehs, K Scherlach, JP Bauer, C Hertweck Angewandte Chemie International Edition 59 (48), 21535-21540, 2020 | 9 | 2020 |
Highly parallelized microfluidic droplet cultivation and prioritization on antibiotic producers from complex natural microbial communities L Mahler, S Niehs, K Martin, T Weber, K Scherlach, M Agler-Rosenbaum, ... BioRxiv, 2019.12. 18.877530, 2019 | 5 | 2019 |
A proteomic approach for the identification of immunotoxic properties of Tulipalin A. P Zwicker, N Schultze, S Niehs, K Methling, M Wurster, D Albrecht, ... Proteomics 16 (23), 2997-3008, 2016 | 5 | 2016 |
Analysis of rhizonin biosynthesis reveals origin of pharmacophoric furylalanine moieties in diverse cyclopeptides FJ Ehinger, SP Niehs, B Dose, M Dell, J Krabbe, SJ Pidot, TP Stinear, ... Angewandte Chemie International Edition 62 (42), e202308540, 2023 | 4 | 2023 |
An in vitro approach for evaluating the immunotoxic potential of Cannabidiol P Zwicker, N Schultze, S Niehs, K Methling, M Wurster, J Bernhardt, ... Toxicology Letters 2 (238), S221, 2015 | 1 | 2015 |
Zinc-starved Brassicaceae Plants Secrete Peptides that Induce Root Expansion S Niehs, J Rajniak, A Johnson, DL Wengier, E Sattely bioRxiv, 2024.06. 11.598559, 2024 | | 2024 |