The ubiquitin code D Komander, M Rape Annual review of biochemistry 81, 203-229, 2012 | 3852 | 2012 |
Breaking the chains: structure and function of the deubiquitinases D Komander, MJ Clague, S Urbé Nature reviews Molecular cell biology 10 (8), 550-563, 2009 | 2323 | 2009 |
Ubiquitin modifications KN Swatek, D Komander Cell research 26 (4), 399-422, 2016 | 1847 | 2016 |
The nuts and bolts of AGC protein kinases LR Pearce, D Komander, DR Alessi Nature reviews Molecular cell biology 11 (1), 9-22, 2010 | 1570 | 2010 |
The emerging complexity of protein ubiquitination D Komander Biochemical society transactions 37 (5), 937-953, 2009 | 1113 | 2009 |
PDK1, the master regulator of AGC kinase signal transduction A Mora, D Komander, DMF van Aalten, DR Alessi Seminars in cell & developmental biology 15 (2), 161-170, 2004 | 1028 | 2004 |
Mechanisms of deubiquitinase specificity and regulation TET Mevissen, D Komander Annual review of biochemistry 86, 159-192, 2017 | 888 | 2017 |
Specific recognition of linear ubiquitin chains by NEMO is important for NF-κB activation S Rahighi, F Ikeda, M Kawasaki, M Akutsu, N Suzuki, R Kato, T Kensche, ... Cell 136 (6), 1098-1109, 2009 | 870 | 2009 |
Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction TL Haas, CH Emmerich, B Gerlach, AC Schmukle, SM Cordier, E Rieser, ... Molecular cell 36 (5), 831-844, 2009 | 858 | 2009 |
Atypical ubiquitylation—the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages Y Kulathu, D Komander Nature reviews Molecular cell biology 13 (8), 508-523, 2012 | 764 | 2012 |
Molecular discrimination of structurally equivalent Lys 63‐linked and linear polyubiquitin chains D Komander, F Reyes‐Turcu, JDF Licchesi, P Odenwaelder, ... EMBO reports 10 (5), 466-473, 2009 | 694 | 2009 |
Breaking the chains: deubiquitylating enzyme specificity begets function MJ Clague, S Urbé, D Komander Nature reviews Molecular cell biology 20 (6), 338-352, 2019 | 657 | 2019 |
OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis TET Mevissen, MK Hospenthal, PP Geurink, PR Elliott, M Akutsu, ... Cell 154 (1), 169-184, 2013 | 589 | 2013 |
Structural insights into the catalytic mechanism of a family 18 exo-chitinase DMF van Aalten, D Komander, B Synstad, S Gåseidnes, MG Peter, ... Proceedings of the National Academy of Sciences 98 (16), 8979-8984, 2001 | 544 | 2001 |
Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains CH Emmerich, A Ordureau, S Strickson, JSC Arthur, PGA Pedrioli, ... Proceedings of the National Academy of Sciences 110 (38), 15247-15252, 2013 | 481 | 2013 |
OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin K Keusekotten, PR Elliott, L Glockner, BK Fiil, RB Damgaard, Y Kulathu, ... Cell 153 (6), 1312-1326, 2013 | 478 | 2013 |
Mechanism of phospho-ubiquitin-induced PARKIN activation T Wauer, M Simicek, A Schubert, D Komander Nature 524 (7565), 370-374, 2015 | 435 | 2015 |
Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2 T Klemm, G Ebert, DJ Calleja, CC Allison, LW Richardson, JP Bernardini, ... The EMBO journal 39 (18), e106275, 2020 | 392 | 2020 |
Molecular basis of USP7 inhibition by selective small-molecule inhibitors AP Turnbull, S Ioannidis, WW Krajewski, A Pinto-Fernandez, C Heride, ... Nature 550 (7677), 481-486, 2017 | 386 | 2017 |
Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne A Bremm, SMV Freund, D Komander Nature structural & molecular biology 17 (8), 939-947, 2010 | 369 | 2010 |