Enhanced Sarcoplasmic Reticulum Ca2+ Leak and Increased Na+-Ca2+ Exchanger Function Underlie Delayed Afterdepolarizations in Patients With Chronic … N Voigt, N Li, Q Wang, W Wang, AW Trafford, I Abu-Taha, Q Sun, ... Circulation 125 (17), 2059-2070, 2012 | 672 | 2012 |
Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation N Voigt, J Heijman, Q Wang, DY Chiang, N Li, M Karck, XHT Wehrens, ... Circulation 129 (2), 145-156, 2014 | 521 | 2014 |
Enhanced cardiomyocyte NLRP3 inflammasome signaling promotes atrial fibrillation C Yao, T Veleva, L Scott Jr, S Cao, L Li, G Chen, P Jeyabal, X Pan, ... Circulation 138 (20), 2227-2242, 2018 | 473 | 2018 |
Calmodulin kinase II–mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice MG Chelu, S Sarma, S Sood, S Wang, RJ Van Oort, DG Skapura, N Li, ... The Journal of clinical investigation 119 (7), 1940-1951, 2009 | 465 | 2009 |
Oxidized Ca2+/Calmodulin-Dependent Protein Kinase II Triggers Atrial Fibrillation A Purohit, AG Rokita, X Guan, B Chen, OM Koval, N Voigt, S Neef, T Sowa, ... Circulation 128 (16), 1748-1757, 2013 | 340 | 2013 |
Role of RyR2 phosphorylation at S2814 during heart failure progression JL Respress, RJ Van Oort, N Li, N Rolim, SS Dixit, A Dealmeida, N Voigt, ... Circulation research 110 (11), 1474-1483, 2012 | 259 | 2012 |
Mutation E169K in junctophilin-2 causes atrial fibrillation due to impaired RyR2 stabilization DL Beavers, W Wang, S Ather, N Voigt, A Garbino, SS Dixit, ... Journal of the American College of Cardiology 62 (21), 2010-2019, 2013 | 205 | 2013 |
Epac2 Mediates Cardiac β1-Adrenergic–Dependent Sarcoplasmic Reticulum Ca2+ Leak and Arrhythmia L Pereira, H Cheng, DH Lao, L Na, RJ Van Oort, JH Brown, XHT Wehrens, ... Circulation 127 (8), 913-922, 2013 | 199 | 2013 |
Ryanodine receptor–mediated calcium leak drives progressive development of an atrial fibrillation substrate in a transgenic mouse model N Li, DY Chiang, S Wang, Q Wang, L Sun, N Voigt, JL Respress, S Ather, ... Circulation 129 (12), 1276-1285, 2014 | 192 | 2014 |
Atrial myocyte NLRP3/CaMKII nexus forms a substrate for postoperative atrial fibrillation J Heijman, AP Muna, T Veleva, CE Molina, H Sutanto, M Tekook, Q Wang, ... Circulation research 127 (8), 1036-1055, 2020 | 188 | 2020 |
Inhibition of CaMKII phosphorylation of RyR2 prevents induction of atrial fibrillation in FKBP12. 6 knockout mice N Li, T Wang, W Wang, MJ Cutler, Q Wang, N Voigt, DS Rosenbaum, ... Circulation research 110 (3), 465-470, 2012 | 165 | 2012 |
Role of inflammatory signaling in atrial fibrillation L Scott Jr, N Li, D Dobrev International journal of cardiology 287, 195-200, 2019 | 161 | 2019 |
Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation SR Cunha, TJ Hund, S Hashemi, N Voigt, N Li, P Wright, O Koval, J Li, ... Circulation 124 (11), 1212-1222, 2011 | 131 | 2011 |
Pitx2-microRNA pathway that delimits sinoatrial node development and inhibits predisposition to atrial fibrillation J Wang, Y Bai, N Li, W Ye, M Zhang, SB Greene, Y Tao, Y Chen, ... Proceedings of the National Academy of Sciences 111 (25), 9181-9186, 2014 | 128 | 2014 |
Loss of microRNA-106b-25 cluster promotes atrial fibrillation by enhancing ryanodine receptor type-2 expression and calcium release DY Chiang, N Kongchan, DL Beavers, KM Alsina, N Voigt, JR Neilson, ... Circulation: Arrhythmia and Electrophysiology 7 (6), 1214-1222, 2014 | 116 | 2014 |
NLRP3 inflammasome is a key driver of obesity-induced atrial arrhythmias L Scott Jr, AC Fender, A Saljic, L Li, X Chen, X Wang, D Linz, J Lang, ... Cardiovascular research 117 (7), 1746-1759, 2021 | 95 | 2021 |
Inflammatory signalling in atrial cardiomyocytes: a novel unifying principle in atrial fibrillation pathophysiology D Dobrev, J Heijman, R Hiram, N Li, S Nattel Nature Reviews Cardiology 20 (3), 145-167, 2023 | 89 | 2023 |
In Vivo Ryr2 Editing Corrects Catecholaminergic Polymorphic Ventricular Tachycardia X Pan, L Philippen, SK Lahiri, C Lee, SH Park, TA Word, N Li, KE Jarrett, ... Circulation research 123 (8), 953-963, 2018 | 79 | 2018 |
Accelerated development of pressure overload–induced cardiac hypertrophy and dysfunction in an RyR2-R176Q knockin mouse model RJ van Oort, JL Respress, N Li, C Reynolds, AC De Almeida, DG Skapura, ... Hypertension 55 (4), 932-938, 2010 | 77 | 2010 |
Inflammasomes and proteostasis novel molecular mechanisms associated with atrial fibrillation N Li, BJJM Brundel Circulation research 127 (1), 73-90, 2020 | 74 | 2020 |