Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis RA Gupta, N Shah, KC Wang, J Kim, HM Horlings, DJ Wong, MC Tsai, ... nature 464 (7291), 1071-1076, 2010 | 5774 | 2010 |
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer K Berns, HM Horlings, BT Hennessy, M Madiredjo, EM Hijmans, K Beelen, ... Cancer cell 12 (4), 395-402, 2007 | 1889 | 2007 |
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters T Hung, Y Wang, MF Lin, AK Koegel, Y Kotake, GD Grant, HM Horlings, ... Nature genetics 43 (7), 621-629, 2011 | 1355 | 2011 |
AACR Project GENIE: powering precision medicine through an international consortium AACR Project Genie Consortium, AACR Project GENIE Consortium, ... Cancer discovery 7 (8), 818-831, 2017 | 1281 | 2017 |
An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer K Stemke-Hale, AM Gonzalez-Angulo, A Lluch, RM Neve, WL Kuo, ... Cancer research 68 (15), 6084-6091, 2008 | 1199 | 2008 |
Dysfunctional CD8 T cells form a proliferative, dynamically regulated compartment within human melanoma H Li, AM van der Leun, I Yofe, Y Lubling, D Gelbard-Solodkin, ... Cell 176 (4), 775-789. e18, 2019 | 869 | 2019 |
Gene expression profiling and histopathological characterization of triple-negative/basal-like breast carcinomas B Kreike, M van Kouwenhove, H Horlings, B Weigelt, H Peterse, ... Breast Cancer Research 9, 1-14, 2007 | 851 | 2007 |
Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck M Persson, Y Andrén, J Mark, HM Horlings, F Persson, G Stenman Proceedings of the National Academy of Sciences 106 (44), 18740-18744, 2009 | 838 | 2009 |
Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial L Voorwerk, M Slagter, HM Horlings, K Sikorska, KK van de Vijver, ... Nature medicine 25 (6), 920-928, 2019 | 724 | 2019 |
Refinement of breast cancer classification by molecular characterization of histological special types B Weigelt, HM Horlings, B Kreike, MM Hayes, M Hauptmann, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2008 | 704 | 2008 |
Assessing tumor-infiltrating lymphocytes in solid tumors: a practical review for pathologists and proposal for a standardized method from the International Immuno-Oncology … S Hendry, R Salgado, T Gevaert, PA Russell, T John, B Thapa, M Christie, ... Advances in anatomic pathology 24 (6), 311-335, 2017 | 696 | 2017 |
Assessing tumor-infiltrating lymphocytes in solid tumors: a practical review for pathologists and proposal for a standardized method from the international immunooncology … S Hendry, R Salgado, T Gevaert, PA Russell, T John, B Thapa, M Christie, ... Advances in anatomic pathology 24 (5), 235-251, 2017 | 623 | 2017 |
Cancer-associated mutations in endometriosis without cancer MS Anglesio, N Papadopoulos, A Ayhan, TM Nazeran, M Noë, ... New England Journal of Medicine 376 (19), 1835-1848, 2017 | 591 | 2017 |
Identification of CMTM6 and CMTM4 as PD-L1 protein regulators R Mezzadra, C Sun, LT Jae, R Gomez-Eerland, E De Vries, W Wu, ... Nature 549 (7670), 106-110, 2017 | 590 | 2017 |
Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets N Turner, MB Lambros, HM Horlings, A Pearson, R Sharpe, R Natrajan, ... Oncogene 29 (14), 2013-2023, 2010 | 462 | 2010 |
MicroRNA sequence and expression analysis in breast tumors by deep sequencing TA Farazi, HM Horlings, JJ Ten Hoeve, A Mihailovic, H Halfwerk, ... Cancer research 71 (13), 4443-4453, 2011 | 421 | 2011 |
Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis LCW Vredeveld, PA Possik, MA Smit, K Meissl, C Michaloglou, ... Genes & development 26 (10), 1055-1069, 2012 | 320 | 2012 |
A case of meningoencephalitis by the relapsing fever spirochaete Borrelia miyamotoi in Europe JWR Hovius, B de Wever, M Sohne, MC Brouwer, J Coumou, ... The Lancet 382 (9892), 658, 2013 | 298 | 2013 |
An acquired vulnerability of drug-resistant melanoma with therapeutic potential L Wang, RL de Oliveira, S Huijberts, E Bosdriesz, N Pencheva, D Brunen, ... Cell 173 (6), 1413-1425. e14, 2018 | 277 | 2018 |
Genetic regulators of large-scale transcriptional signatures in cancer AS Adler, M Lin, H Horlings, DSA Nuyten, MJ van de Vijver, HY Chang Nature genetics 38 (4), 421-430, 2006 | 273 | 2006 |