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Azamat Rizuan
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Principles governing the phase separation of multidomain proteins
P Mohanty, U Kapoor, D Sundaravadivelu Devarajan, TM Phan, A Rizuan, ...
Biochemistry 61 (22), 2443-2455, 2022
462022
Expanding the molecular language of protein liquid–liquid phase separation
S Rekhi, CG Garcia, M Barai, A Rizuan, BS Schuster, KL Kiick, J Mittal
Nature Chemistry, 1-12, 2024
272024
A Zn‐dependent structural transition of SOD1 modulates its ability to undergo phase separation
B Das, S Roychowdhury, P Mohanty, A Rizuan, J Chakraborty, J Mittal, ...
The EMBO Journal 42 (2), e111185, 2023
232023
Molecular interactions underlying the phase separation of HP1α: role of phosphorylation, ligand and nucleic acid binding
C Her, TM Phan, N Jovic, U Kapoor, BE Ackermann, A Rizuan, YC Kim, ...
Nucleic Acids Research 50 (22), 12702-12722, 2022
232022
A synergy between site-specific and transient interactions drives the phase separation of a disordered, low-complexity domain
P Mohanty*, J Shenoy*, A Rizuan*, JF Mercado-Ortiz, NL Fawzi, J Mittal
Proceedings of the National Academy of Sciences 120 (34), e2305625120, 2023
212023
Multiscale simulations reveal TDP-43 molecular-level interactions driving condensation
HI Ingólfsson, A Rizuan, X Liu, P Mohanty, PCT Souza, SJ Marrink, ...
Biophysical Journal 122 (22), 4370-4381, 2023
132023
Developing bonded potentials for a coarse-grained model of intrinsically disordered proteins
A Rizuan, N Jovic, TM Phan, YC Kim, J Mittal
Journal of chemical information and modeling 62 (18), 4474-4485, 2022
102022
A complex network of interdomain interactions underlies the conformational ensemble of monomeric TDP‐43 and modulates its phase behavior
P Mohanty*, A Rizuan*, YC Kim, NL Fawzi, J Mittal
Protein Science, e4891, 2023
92023
Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates
X Yan, D Kuster, P Mohanty, J Nijssen, K Pombo-García, A Rizuan, ...
bioRxiv, 2024
62024
Uncovering the molecular language of protein liquid-liquid phase separation
S Rekhi, C Garcia, M Barai, A Rizuan, BS Schuster, KL Kiick, J Mittal
Biophysical Journal 123 (3), 444a-445a, 2024
2024
Structural details of helix-mediated TDP-43 C-terminal domain multimerization
A Rizuan, J Shenoy, P Mohanty, PMS Dos Passos, JFM Ortiz, L Bai, ...
bioRxiv, 2024
2024
Elucidating residue level contributions to phase separation using a model polypeptide
S Rekhi, C Garcia, M Barai, A Rizuan, BS Schuster, K Kiick, J Mittal
Biophysical Journal 122 (3), 206a, 2023
2023
Hydrophobic residues in disordered and helical regions mediate the oligomerization and phase separation of TDP-43 C-terminal domain
P Mohanty, J Shenoy, A Rizuan, N Jovic, J Mercado-Ortiz, NL Fawzi, ...
Biophysical Journal 122 (3), 208a, 2023
2023
Multiscale simulations of TDP-43 full-length uncover molecular determinants of its phase separation beyond N/C-terminal oligomerization
A Rizuan, P Mohanty, NL Fawzi, J Mittal
Biophysical Journal 122 (3), 209a, 2023
2023
Cofactor-dependent structural transition of SOD1 modulates its ability to undergo liquid-liquid phase separation
S Roychowdhury, B Das, P Mohanty, A Rizuan, J Mittal, K Chattopadhyay
Biophysical Journal 122 (3), 353a, 2023
2023
Implementing Transferable Backbone Potentials for a Coarse-Grained Model of Intrinsically Disordered Proteins
A Rizuan, N Jovic, YC Kim, J Mittal
2022 Biophysical Society (BPS) Annual Meeting, 2022
2022
Multiscale simulations reveal molecular dynamics of TDP-43 assemblies
HI Ingólfsson, A Rizuan, P Mohanty, J Mittal, J Berry
Biophysical Journal 121 (3), 55a, 2022
2022
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