m6A facilitates hippocampus-dependent learning and memory through YTHDF1 H Shi, X Zhang, YL Weng, Z Lu, Y Liu, Z Lu, J Li, P Hao, Y Zhang, F Zhang, ... Nature 563 (7730), 249-253, 2018 | 460 | 2018 |
Efficient base editing in methylated regions with a human APOBEC3A-Cas9 fusion X Wang, J Li, Y Wang, B Yang, J Wei, J Wu, R Wang, X Huang, J Chen, ... Nature biotechnology 36 (10), 946-949, 2018 | 267 | 2018 |
Correction of the Marfan syndrome pathogenic FBN1 mutation by base editing in human cells and heterozygous embryos Y Zeng, J Li, G Li, S Huang, W Yu, Y Zhang, D Chen, J Chen, J Liu, ... Molecular therapy 26 (11), 2631-2637, 2018 | 170 | 2018 |
Efficient generation of mouse models of human diseases via ABE-and BE-mediated base editing Z Liu, Z Lu, G Yang, S Huang, G Li, S Feng, Y Liu, J Li, W Yu, Y Zhang, ... Nature communications 9 (1), 2338, 2018 | 157 | 2018 |
A pan-cancer single-cell panorama of human natural killer cells F Tang, J Li, L Qi, D Liu, Y Bo, S Qin, Y Miao, K Yu, W Hou, J Li, J Peng, ... Cell 186 (19), 4235-4251. e20, 2023 | 126 | 2023 |
Highly efficient and precise base editing in discarded human tripronuclear embryos G Li, Y Liu, Y Zeng, J Li, L Wang, G Yang, D Chen, X Shang, J Chen, ... Protein & Cell 8 (10), 776-779, 2017 | 96 | 2017 |
Structure-guided engineering of adenine base editor with minimized RNA off-targeting activity J Li, W Yu, S Huang, S Wu, L Li, J Zhou, Y Cao, X Huang, Y Qiao Nature Communications 12 (1), 2287, 2021 | 58 | 2021 |
Base-editing-mediated R17H substitution in histone H3 reveals methylation-dependent regulation of Yap signaling and early mouse embryo development G Yang, C Zhou, R Wang, S Huang, Y Wei, X Yang, Y Liu, J Li, Z Lu, ... Cell reports 26 (2), 302-312. e4, 2019 | 34 | 2019 |
Developing ABEmax-NG with precise targeting and expanded editing scope to model pathogenic splice site mutations in vivo S Huang, Z Liao, X Li, Z Liu, G Li, J Li, Z Lu, Y Zhang, X Li, X Ma, Q Sun, ... Iscience 15, 640-648, 2019 | 28 | 2019 |
Efficient base editing in G/C-rich regions to model androgen insensitivity syndrome J Li, Z Liu, S Huang, X Wang, G Li, Y Xu, W Yu, S Chen, Y Zhang, H Ma, ... Cell Research 29 (2), 174-176, 2019 | 18 | 2019 |
Functional phosphoproteomics in cancer chemoresistance using CRISPR‐mediated base editors J Li, J Lin, S Huang, M Li, W Yu, Y Zhao, J Guo, P Zhang, X Huang, ... Advanced Science 9 (30), 2200717, 2022 | 16 | 2022 |
Cross-tissue human fibroblast atlas reveals myofibroblast subtypes with distinct roles in immune modulation Y Gao, J Li, W Cheng, T Diao, H Liu, Y Bo, C Liu, W Zhou, M Chen, ... Cancer Cell 42 (10), 1764-1783. e10, 2024 | 13 | 2024 |
Generation of isogenic single and multiplex gene knockout mice by base editing-induced STOP G Yang, T Zhu, Z Lu, G Li, H Zhang, S Feng, Y Liu, J Li, Y Zhang, J Chen, ... Science bulletin 63 (17), 1101-1107, 2018 | 12 | 2018 |
Allele-specific genome editing of imprinting genes by preferentially targeting non-methylated loci using Staphylococcus aureus Cas9 (SaCas9) Y Liu, J Li, C Zhou, B Meng, Y Wei, G Yang, Z Lu, Q Shen, Y Zhang, ... Science Bulletin 64 (21), 1592-1600, 2019 | 10 | 2019 |
Harnessing A3G for efficient and selective C-to-T conversion at C-rich sequences W Yu, J Li, S Huang, X Li, P Li, G Li, A Liang, T Chi, X Huang BMC biology 19, 1-11, 2021 | 9 | 2021 |
FUSION PROTEINS FOR BASE EDITING C Jia, Y Li, H Xingxu, Y Bei, W Xiao, LI Jianan | | 2019 |
REAGENT AND METHOD FOR REPAIRING FBN1T7498C MUTATION USING BASE EDITING H Xingxu, LI Guanglei, LI Jianan | | 2018 |