Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E AC Hsieh, M Costa, O Zollo, C Davis, ME Feldman, JR Testa, O Meyuhas, ... Cancer cell 17 (3), 249-261, 2010 | 537 | 2010 |
Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency M Barna, A Pusic, O Zollo, M Costa, N Kondrashov, E Rego, PH Rao, ... Nature 456 (7224), 971-975, 2008 | 509 | 2008 |
Roles of hydrogen peroxide in thyroid physiology and disease Y Song, N Driessens, M Costa, X De Deken, V Detours, B Corvilain, ... The Journal of Clinical Endocrinology & Metabolism 92 (10), 3764-3773, 2007 | 285 | 2007 |
Characterization of Cre recombinase activity for in vivo targeting of adipocyte precursor cells KC Krueger, MJ Costa, H Du, BJ Feldman Stem cell reports 3 (6), 1147-1158, 2014 | 109 | 2014 |
Circadian rhythm gene period 3 is an inhibitor of the adipocyte cell fate MJ Costa, AYL So, K Kaasik, KC Krueger, ML Pillsbury, YH Fu, LJ Ptacek, ... Journal of biological chemistry 286 (11), 9063-9070, 2011 | 104 | 2011 |
The circadian clock regulates adipogenesis by a Per3 crosstalk pathway to Klf15 A Aggarwal, MJ Costa, B Rivero-Gutiérrez, L Ji, SL Morgan, BJ Feldman Cell reports 21 (9), 2367-2375, 2017 | 71 | 2017 |
A novel CXCR4 antagonist IgG1 antibody (PF-06747143) for the treatment of hematologic malignancies SH Liu, Y Gu, B Pascual, Z Yan, M Hallin, C Zhang, C Fan, W Wang, ... Blood advances 1 (15), 1088-1100, 2017 | 46 | 2017 |
Oncogenic mutations in the thyrotropin receptor of autonomously functioning thyroid nodules in the Japanese population V Vanvooren, S Uchino, L Duprez, MJ Costa, J Vandekerckhove, J Parma, ... European journal of endocrinology 147 (3), 287-291, 2002 | 45 | 2002 |
Role of caveolin-1 in thyroid phenotype, cell homeostasis, and hormone synthesis: in vivo study of caveolin-1 knockout mice M Senou, MJ Costa, C Massart, M Thimmesch, C Khalifa, S Poncin, ... American Journal of Physiology-Endocrinology and Metabolism 297 (2), E438-E451, 2009 | 43 | 2009 |
Immunohistochemical study of heat shock proteins 27, 60 and 70 in the normal human adrenal and in adrenal tumors with suppressed ACTH production D Pignatelli, J Ferreira, P Soares, M José Costa, M Conceição Magalhães Microscopy research and technique 61 (3), 315-323, 2003 | 43 | 2003 |
A glucocorticoid-and diet-responsive pathway toggles adipocyte precursor cell activity in vivo JC Wong, KC Krueger, MJ Costa, A Aggarwal, H Du, TL McLaughlin, ... Science signaling 9 (451), ra103-ra103, 2016 | 35 | 2016 |
Sphingolipid-cholesterol domains (lipid rafts) in normal human and dog thyroid follicular cells are not involved in thyrotropin receptor signaling MJ Costa, Y Song, P Macours, C Massart, MC Many, S Costagliola, ... Endocrinology 145 (3), 1464-1472, 2004 | 32 | 2004 |
Kinetics of thyrotropin-stimulating hormone (TSH) and thyroid-stimulating antibody binding and action on the TSH receptor in intact TSH receptor-expressing CHO cells J Van Sande, MJ Costa, C Massart, S Swillens, S Costagliola, J Orgiazzi, ... The Journal of Clinical Endocrinology & Metabolism 88 (11), 5366-5374, 2003 | 21 | 2003 |
Notch4 is required for tumor onset and perfusion MJ Costa, X Wu, H Cuervo, R Srinivasan, SK Bechis, E Cheang, ... Vascular cell 5, 1-10, 2013 | 20 | 2013 |
Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugates MJ Costa, J Kudaravalli, JT Ma, WH Ho, K Delaria, C Holz, A Stauffer, ... Scientific Reports 9 (1), 2443, 2019 | 18 | 2019 |
A mouse model for evaluation of efficacy and concomitant toxicity of anti-human CXCR4 therapeutics MJ Costa, J Kudaravalli, WH Liu, J Stock, S Kong, SH Liu PLoS One 13 (3), e0194688, 2018 | 15 | 2018 |
Using SRM-MS to quantify nuclear protein abundance differences between adipose tissue depots of insulin-resistant mice A Ota, KM Kovary, OH Wu, R Ahrends, WJ Shen, MJ Costa, BJ Feldman, ... Journal of lipid research 56 (5), 1068-1078, 2015 | 12 | 2015 |
Reciprocal negative regulation between thyrotropin/3′, 5′-cyclic adenosine monophosphate-mediated proliferation and caveolin-1 expression in human and murine thyrocytes MJ Costa, M Senou, F Van Rode, J Ruf, M Capello, D Dequanter, ... Molecular endocrinology 21 (4), 921-932, 2007 | 11 | 2007 |
Mutated E-cadherin: genomic and functional characterization in thyroid cells from the KAT family A Sofia Rocha, O De Wever, S Moreira, MJ Costa, J Vandekerckhove, ... Thyroid 14 (11), 902-909, 2004 | 7 | 2004 |
IO-108, A fully human therapeutic antibody blocking the myeloid checkpoint LILRB2/ILT4, promotes innate and adaptive anti-cancer immunity in preclinical studies JT Ma, X Liu, R Stafford, K McCutcheon, H Chen, T Huang, H Tian, ... Cancer Res 82 (12_suppl), 601-601, 2022 | 3 | 2022 |