Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfaces H Venselaar, TAH Te Beek, RKP Kuipers, ML Hekkelman, G Vriend BMC bioinformatics 11, 1-10, 2010 | 1094 | 2010 |
A series of PDB related databases for everyday needs RP Joosten, TAH Te Beek, E Krieger, ML Hekkelman, RWW Hooft, ... Nucleic acids research 39 (suppl_1), D411-D419, 2010 | 865 | 2010 |
AlphaFill: enriching the AlphaFold models with ligands and co-factors ML Hekkelman, I de Vries, RP Joosten, A Perrakis bioRxiv, 2021 | 254 | 2021 |
The CCP4 suite: integrative software for macromolecular crystallography J Agirre, M Atanasova, H Bagdonas, CB Ballard, A Baslé, ... Acta Crystallographica Section D: Structural Biology 79 (6), 449-461, 2023 | 183 | 2023 |
WIWS: a protein structure bioinformatics Web service collection ML Hekkelman, TAH te Beek, SR Pettifer, D Thorne, TK Attwood, G Vriend Nucleic acids research 38 (suppl_2), W719-W723, 2010 | 170 | 2010 |
Identification of novel functional TBP‐binding sites and general factor repertoires S Denissov, M Van Driel, R Voit, M Hekkelman, T Hulsen, N Hernandez, ... The EMBO journal 26 (4), 944-954, 2007 | 141 | 2007 |
A global Ramachandran score identifies protein structures with unlikely stereochemistry OV Sobolev, PV Afonine, NW Moriarty, ML Hekkelman, RP Joosten, ... Structure 28 (11), 1249-1258. e2, 2020 | 117 | 2020 |
Homology modelling and spectroscopy, a never-ending love story H Venselaar, RP Joosten, B Vroling, CAB Baakman, ML Hekkelman, ... European Biophysics Journal 39, 551-563, 2010 | 87 | 2010 |
The EMBRACE web service collection S Pettifer, J Ison, M Kalaš, D Thorne, P McDermott, I Jonassen, A Liaquat, ... Nucleic acids research 38 (suppl_2), W683-W688, 2010 | 47 | 2010 |
MRS: a fast and compact retrieval system for biological data ML Hekkelman, G Vriend Nucleic Acids Research 33 (suppl_2), W766-W769, 2005 | 44 | 2005 |
Functional radiogenetic profiling implicates ERCC6L2 in non-homologous end joining P Francica, M Mutlu, VA Blomen, C Oliveira, Z Nowicka, A Trenner, ... Cell reports 32 (8), 2020 | 36 | 2020 |
Homology-based loop modeling yields more complete crystallographic protein structures B van Beusekom, K Joosten, ML Hekkelman, RP Joosten, A Perrakis IUCrJ 5 (5), 585-594, 2018 | 31 | 2018 |
The cohesin acetylation cycle controls chromatin loop length through a PDS5A brake mechanism MS van Ruiten, D van Gent, Á Sedeño Cacciatore, A Fauster, L Willems, ... Nature structural & molecular biology 29 (6), 586-591, 2022 | 28 | 2022 |
Building and rebuilding N-glycans in protein structure models B van Beusekom, N Wezel, ML Hekkelman, A Perrakis, P Emsley, ... Acta Crystallographica Section D: Structural Biology 75 (4), 416-425, 2019 | 23 | 2019 |
Signature, a web server for taxonomic characterization of sequence samples using signature genes BE Dutilh, Y He, ML Hekkelman, MA Huynen Nucleic acids research 36 (suppl_2), W470-W474, 2008 | 19 | 2008 |
3D-Beacons: decreasing the gap between protein sequences and structures through a federated network of protein structure data resources M Varadi, S Nair, I Sillitoe, G Tauriello, S Anyango, S Bienert, C Borges, ... GigaScience 11, giac118, 2022 | 11 | 2022 |
GeneE: gene and protein query expansion with disambiguation MJ Schuemie, N Kang, ML Hekkelman, JA Kors Bioinformatics 26 (1), 147-148, 2010 | 9 | 2010 |
Analysis and validation of overall N-glycan conformation in Privateer JS Dialpuri, H Bagdonas, M Atanasova, LC Schofield, ML Hekkelman, ... Acta Crystallographica Section D: Structural Biology 79 (6), 2023 | 8 | 2023 |
New restraints and validation approaches for nucleic acid structures in PDB-REDO I de Vries, T Kwakman, XJ Lu, ML Hekkelman, M Deshpande, S Velankar, ... Acta Crystallographica Section D: Structural Biology 77 (9), 1127-1141, 2021 | 7 | 2021 |
FIRRM/C1orf112 mediates resolution of homologous recombination intermediates in response to DNA interstrand crosslinks A Mazouzi, SC Moser, F Abascal, B van den Broek, ... Science Advances 9 (22), eadf4409, 2023 | 6 | 2023 |