Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ L Nagy, P Tontonoz, JGA Alvarez, H Chen, RM Evans Cell 93 (2), 229-240, 1998 | 2348 | 1998 |
Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300 H Chen, RJ Lin, RL Schiltz, D Chakravarti, A Nash, L Nagy, ML Privalsky, ... Cell 90 (3), 569-580, 1997 | 1887 | 1997 |
Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase H Chen, RJ Lin, W Xie, D Wilpitz, RM Evans Cell 98 (5), 675-686, 1999 | 849 | 1999 |
The histone acetylase PCAF is a nuclear receptor coactivator JCG Blanco, S Minucci, J Lu, XJ Yang, KK Walker, H Chen, RM Evans, ... Genes & development 12 (11), 1638-1651, 1998 | 526 | 1998 |
A transcriptional switch mediated by cofactor methylation W Xu, H Chen, K Du, H Asahara, M Tini, BM Emerson, M Montminy, ... Science 294 (5551), 2507-2511, 2001 | 509 | 2001 |
Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators SJ Demarest, M Martinez-Yamout, J Chung, H Chen, W Xu, HJ Dyson, ... Nature 415 (6871), 549-553, 2002 | 495 | 2002 |
A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity D Chakravarti, V Ogryzko, HY Kao, A Nash, H Chen, Y Nakatani, ... Cell 96 (3), 393-403, 1999 | 425 | 1999 |
Genome-wide analysis of chromosomal features repressing human immunodeficiency virus transcription MK Lewinski, D Bisgrove, P Shinn, H Chen, C Hoffmann, S Hannenhalli, ... Journal of virology 79 (11), 6610-6619, 2005 | 339 | 2005 |
ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance MC Louie, JX Zou, A Rabinovich, HW Chen Molecular and cellular biology 24 (12), 5157-5171, 2004 | 330 | 2004 |
A long noncoding RNA connects c-Myc to tumor metabolism CL Hung, LY Wang, YL Yu, HW Chen, S Srivastava, G Petrovics, HJ Kung Proceedings of the National Academy of Sciences 111 (52), 18697-18702, 2014 | 308 | 2014 |
Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein Y Xia, GM Pao, HW Chen, IM Verma, T Hunter Journal of Biological Chemistry 278 (7), 5255-5263, 2003 | 253 | 2003 |
Interleukin-8 confers androgen-independent growth and migration of LNCaP: differential effects of tyrosine kinases Src and FAK LF Lee, MC Louie, SJ Desai, J Yang, HW Chen, CP Evans, HJ Kung Oncogene 23 (12), 2197-2205, 2004 | 243 | 2004 |
Kinesin family deregulation coordinated by bromodomain protein ANCCA and histone methyltransferase MLL for breast cancer cell growth, survival, and tamoxifen resistance JX Zou, Z Duan, J Wang, A Sokolov, J Xu, CZ Chen, JJ Li, HW Chen Molecular Cancer Research 12 (4), 539-549, 2014 | 238 | 2014 |
HATs on and beyond chromatin H Chen, M Tini, RM Evans Current opinion in cell biology 13 (2), 218-224, 2001 | 231 | 2001 |
The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression L Qin, L Liao, A Redmond, L Young, Y Yuan, H Chen, BW O'Malley, J Xu Molecular and cellular biology 28 (19), 5937-5950, 2008 | 222 | 2008 |
KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation DA Hsia, CG Tepper, MR Pochampalli, EYC Hsia, C Izumiya, SB Huerta, ... Proceedings of the National Academy of Sciences 107 (21), 9671-9676, 2010 | 205 | 2010 |
MicroRNA let-7c is downregulated in prostate cancer and suppresses prostate cancer growth N Nadiminty, R Tummala, W Lou, Y Zhu, XB Shi, JX Zou, H Chen, J Zhang, ... PloS one 7 (3), e32832, 2012 | 200 | 2012 |
Androgen-induced recruitment of RNA polymerase II to a nuclear receptor–p160 coactivator complex MC Louie, HQ Yang, AH Ma, W Xu, JX Zou, HJ Kung, HW Chen Proceedings of the National Academy of Sciences 100 (5), 2226-2230, 2003 | 197 | 2003 |
Histone methyltransferase NSD2/MMSET mediates constitutive NF-κB signaling for cancer cell proliferation, survival, and tumor growth via a feed-forward loop P Yang, L Guo, ZJ Duan, CG Tepper, L Xue, X Chen, HJ Kung, AC Gao, ... Molecular and cellular biology 32 (15), 3121-3131, 2012 | 193 | 2012 |
ROR-[gamma] drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer J Wang, JX Zou, X Xue, D Cai, Y Zhang, Z Duan, Q Xiang, JC Yang, ... Nature medicine 22 (5), 488-496, 2016 | 187 | 2016 |