Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generation A Heikal, Y Nakatani, E Dunn, MR Weimar, CL Day, EN Baker, JS Lott, ... Molecular microbiology 91 (5), 950-964, 2014 | 140 | 2014 |
Oxidative phosphorylation as a target space for tuberculosis: success, caution, and future directions GM Cook, K Hards, E Dunn, A Heikal, Y Nakatani, C Greening, DC Crick, ... Tuberculosis and the Tubercle Bacillus, 295-316, 2017 | 95 | 2017 |
Regulation of proline metabolism in mycobacteria and its role in carbon metabolism under hypoxia M Berney, MR Weimar, A Heikal, GM Cook Molecular microbiology 84 (4), 664-681, 2012 | 79 | 2012 |
The mechanism of catalysis by type-II NADH: quinone oxidoreductases JN Blaza, HR Bridges, D Aragão, EA Dunn, A Heikal, GM Cook, ... Scientific reports 7 (1), 40165, 2017 | 65 | 2017 |
Incorporation of triphenylphosphonium functionality improves the inhibitory properties of phenothiazine derivatives in Mycobacterium tuberculosis EA Dunn, M Roxburgh, L Larsen, RAJ Smith, AD McLellan, A Heikal, ... Bioorganic & medicinal chemistry 22 (19), 5320-5328, 2014 | 54 | 2014 |
Activation of type II NADH dehydrogenase by quinolinequinones mediates antitubercular cell death A Heikal, K Hards, CY Cheung, A Menorca, MSM Timmer, BL Stocker, ... Journal of Antimicrobial Chemotherapy 71 (10), 2840-2847, 2016 | 48 | 2016 |
Synthesis and preclinical evaluation of TPA-based zinc chelators as metallo-β-lactamase inhibitors C Schnaars, G Kildahl-Andersen, A Prandina, R Popal, S Radix, ... ACS Infectious Diseases 4 (9), 1407-1422, 2018 | 43 | 2018 |
Oxidative phosphorylation as a target space for tuberculosis: success, caution, and future directions. Microbiol Spectr 5 GM Cook, K Hards, E Dunn, A Heikal, Y Nakatani, C Greening, DC Crick, ... TBTB2–0014-2016, 2017 | 28 | 2017 |
ZN148 Is a Modular Synthetic Metallo-β-Lactamase Inhibitor That Reverses Carbapenem Resistance in Gram-Negative Pathogens In Vivo Ø Samuelsen, OAH Åstrand, C Fröhlich, A Heikal, S Skagseth, ... Antimicrobial Agents and Chemotherapy 64 (6), 10.1128/aac. 02415-19, 2020 | 27 | 2020 |
Multiple bactericidal mechanisms of the zinc ionophore PBT2 N Harbison-Price, SA Ferguson, A Heikal, G Taiaroa, K Hards, Y Nakatani, ... Msphere 5 (2), 10.1128/msphere. 00157-20, 2020 | 23 | 2020 |
Bacillus cereus biofilm formation on central venous catheters of hospitalised cardiac patients S Ikram, A Heikal, S Finke, A Hofgaard, Y Rehman, AN Sabri, OA Økstad Biofouling 35 (2), 204-216, 2019 | 23 | 2019 |
The stabilisation of purified, reconstituted P-glycoprotein by freeze drying with disaccharides A Heikal, K Box, A Rothnie, J Storm, R Callaghan, M Allen Cryobiology 58 (1), 37-44, 2009 | 22 | 2009 |
Metal chelation by a plant lignan, secoisolariciresinol diglucoside F Fucassi, A Heikal, LI Mikhalovska, G Standen, IU Allan, SV Mikhalovsky, ... Journal of Inclusion Phenomena and Macrocyclic Chemistry 80, 345-351, 2014 | 18 | 2014 |
‘Tethering’fragment-based drug discovery to identify inhibitors of the essential respiratory membrane protein type II NADH dehydrogenase A Heikal, Y Nakatani, W Jiao, C Wilson, D Rennison, MR Weimar, ... Bioorganic & medicinal chemistry letters 28 (13), 2239-2243, 2018 | 12 | 2018 |
Substituted sulfonamide bioisosteres of 8-hydroxyquinoline as zinc-dependent antibacterial compounds JE McGowan, AD Harper, EK Davison, JY Jeong, S Mros, ... Bioorganic & Medicinal Chemistry Letters 30 (11), 127110, 2020 | 10 | 2020 |
Complete genome sequence of pseudomonas aeruginosa K34-7, a carbapenem-resistant isolate of the high-risk sequence type 233 G Taiaroa, Ø Samuelsen, T Kristensen, OAL Økstad, A Heikal Microbiology Resource Announcements 7 (4), 10.1128/mra. 00886-18, 2018 | 10 | 2018 |
Complete Genome Sequence of a Multidrug-Resistant, blaNDM-1-Expressing Klebsiella pneumoniae K66-45 Clinical Isolate from Norway A Heikal, Ø Samuelsen, T Kristensen, OA Økstad Genome Announcements 5 (27), 10.1128/genomea. 00601-17, 2017 | 7 | 2017 |
Drug Discovery & Development: State-of-the-Art and Future Directions” on the topic of “Targets”: OXPHOS as a target space for tuberculosis: success, caution, and future directions GM Cook, K Hards, E Dunn, A Heikal, Y Nakatani, C Greening, DC Crick, ... Microbiology spectrum 5 (3), 2017 | 6 | 2017 |
Microtiter screening reveals oxygen-dependent antimicrobial activity of natural products against mastitis-causing bacteria SA Ferguson, A Menorca, EM Van Zuylen, CY Cheung, MA McConnell, ... Frontiers in microbiology 10, 1995, 2019 | 5 | 2019 |
Comparison of lipid and detergent enzyme environments for identifying inhibitors of membrane-bound energy-transducing proteins EA Dunn, GM Cook, A Heikal Journal of microbiological methods 120, 41-43, 2016 | 5 | 2016 |