Unruptured intracranial aneurysms—risk of rupture and risks of surgical intervention International Study of Unruptured Intracranial Aneurysms Investigators New England Journal of Medicine 339 (24), 1725-1733, 1998 | 1582 | 1998 |
Glutamate receptors, neurotoxicity and neurodegeneration A Lau, M Tymianski Pflügers Archiv-European Journal of Physiology 460, 525-542, 2010 | 1391 | 2010 |
Treatment of ischemic brain damage by perturbing NMDA receptor-PSD-95 protein interactions M Aarts, Y Liu, L Liu, S Besshoh, M Arundine, JW Gurd, YT Wang, ... Science 298 (5594), 846-850, 2002 | 1252 | 2002 |
Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity M Arundine, M Tymianski Cell calcium 34 (4-5), 325-337, 2003 | 1096 | 2003 |
Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein R Sattler, Z Xiong, WY Lu, M Hafner, JF MacDonald, M Tymianski Science 284 (5421), 1845-1848, 1999 | 1088 | 1999 |
NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo Y Liu, TP Wong, M Aarts, A Rooyakkers, L Liu, TW Lai, DC Wu, J Lu, ... Journal of Neuroscience 27 (11), 2846-2857, 2007 | 998 | 2007 |
Calcium, ischemia and excitotoxicity K Szydlowska, M Tymianski Cell calcium 47 (2), 122-129, 2010 | 969 | 2010 |
A key role for TRPM7 channels in anoxic neuronal death M Aarts, K Iihara, WL Wei, ZG Xiong, M Arundine, W Cerwinski, ... Cell 115 (7), 863-877, 2003 | 941 | 2003 |
Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury M Arundine, M Tymianski Cellular and Molecular Life Sciences CMLS 61, 657-668, 2004 | 889 | 2004 |
Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons M Tymianski, MP Charlton, PL Carlen, CH Tator Journal of Neuroscience 13 (5), 2085-2104, 1993 | 761 | 1993 |
Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death R Sattler, M Tymianski Molecular neurobiology 24, 107-129, 2001 | 739 | 2001 |
Molecular mechanisms of calcium-dependent excitotoxicity R Sattler, M Tymianski Journal of molecular medicine 78, 3-13, 2000 | 644 | 2000 |
Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial MD Hill, M Goyal, BK Menon, RG Nogueira, RA McTaggart, AM Demchuk, ... The Lancet 395 (10227), 878-887, 2020 | 499 | 2020 |
Normal and abnormal calcium homeostasis in neurons: a basis for the pathophysiology of traumatic and ischemic central nervous system injury M Tymianski, CH Tator Neurosurgery 38 (6), 1176-1195, 1996 | 492 | 1996 |
The natural history and predictive features of hemorrhage from brain arteriovenous malformations L da Costa, MC Wallace, KG Ter Brugge, C O'Kelly, RA Willinsky, ... Stroke 40 (1), 100-105, 2009 | 484 | 2009 |
Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain DJ Cook, L Teves, M Tymianski Nature 483 (7388), 213-217, 2012 | 472 | 2012 |
Safety and efficacy of NA-1 in patients with iatrogenic stroke after endovascular aneurysm repair (ENACT): a phase 2, randomised, double-blind, placebo-controlled trial MD Hill, RH Martin, D Mikulis, JH Wong, FL Silver, G Milot, WM Clark, ... The Lancet Neurology 11 (11), 942-950, 2012 | 420 | 2012 |
Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity R Sattler, MP Charlton, M Hafner, M Tymianski Journal of neurochemistry 71 (6), 2349-2364, 1998 | 361 | 1998 |
Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia HS Sun, MF Jackson, LJ Martin, K Jansen, L Teves, H Cui, S Kiyonaka, ... Nature neuroscience 12 (10), 1300-1307, 2009 | 317 | 2009 |
Distinct roles of synaptic and extrasynaptic NMDA receptors in excitotoxicity R Sattler, Z Xiong, WY Lu, JF MacDonald, M Tymianski Journal of Neuroscience 20 (1), 22-33, 2000 | 311 | 2000 |