Fibroblast-specific genetic manipulation of p38 mitogen-activated protein kinase in vivo reveals its central regulatory role in fibrosis JD Molkentin, D Bugg, N Ghearing, LE Dorn, P Kim, MA Sargent, ... Circulation 136 (6), 549-561, 2017 | 285 | 2017 |
Mitochondrial dysfunction in macrophages promotes inflammation and suppresses repair after myocardial infarction S Cai, M Zhao, B Zhou, A Yoshii, D Bugg, O Villet, A Sahu, GS Olson, ... The Journal of clinical investigation 133 (4), 2023 | 103 | 2023 |
Regulators of cardiac fibroblast cell state R Bretherton, D Bugg, E Olszewski, J Davis Matrix Biology 91, 117-135, 2020 | 55 | 2020 |
Infarct collagen topography regulates fibroblast fate via p38-yes-associated protein transcriptional enhanced associate domain signals D Bugg, R Bretherton, P Kim, E Olszewski, A Nagle, AE Schumacher, ... Circulation research 127 (10), 1306-1322, 2020 | 54 | 2020 |
Antigen presentation by cardiac fibroblasts promotes cardiac dysfunction N Ngwenyama, K Kaur, D Bugg, B Theall, M Aronovitz, R Berland, ... Nature cardiovascular research 1 (8), 761-774, 2022 | 50 | 2022 |
MBNL1 drives dynamic transitions between fibroblasts and myofibroblasts in cardiac wound healing D Bugg, LRJ Bailey, RC Bretherton, KE Beach, IM Reichardt, KZ Robeson, ... Cell Stem Cell 29 (3), 419-433. e10, 2022 | 41 | 2022 |
User‐controlled 4D biomaterial degradation with substrate‐selective sortase transpeptidases for single‐cell biology RC Bretherton, AJ Haack, I Kopyeva, F Rahman, JD Kern, D Bugg, ... Advanced Materials 35 (19), 2209904, 2023 | 19 | 2023 |
Engrafted Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes Undergo Clonal Expansion In Vivo D El-Nachef, D Bugg, KM Beussman, S Steczina, AM Martinson, CE Murry, ... Circulation 143 (16), 1635-1638, 2021 | 12 | 2021 |
Fibroblast-Specific Genetic Manipulation of p38 mitogen-activated protein kinase JD Molkentin, D Bugg, N Ghearing, LE Dorn, P Kim, MA Sargent, ... vivo, 2017 | 8 | 2017 |
MBNL1 regulates programmed postnatal switching between regenerative and differentiated cardiac states LRJ Bailey, D Bugg, IM Reichardt, CD Ortaç, A Nagle, J Gunaje, ... Circulation 149 (23), 1812-1829, 2024 | 6 | 2024 |
Network model integrated with multi-omic data predicts MBNL1 signals that drive myofibroblast activation AR Nelson, D Bugg, J Davis, JJ Saucerman Iscience 26 (4), 2023 | 3 | 2023 |
Correcting dilated cardiomyopathy with fibroblast-targeted p38 deficiency RC Bretherton, IM Reichardt, KA Zabrecky, AJ Goldstein, LRJ Bailey, ... bioRxiv, 2023.01. 23.523684, 2023 | 3 | 2023 |
Sox9-coordinated cellular neighborhoods generate fibrosis D Bugg, J Davis Cell Stem Cell 31 (5), 589-590, 2024 | | 2024 |
User‐Controlled 4D Biomaterial Degradation with Substrate‐Selective Sortase Transpeptidases for Single‐Cell Biology (Adv. Mater. 19/2023) RC Bretherton, AJ Haack, I Kopyeva, F Rahman, JD Kern, D Bugg, ... Advanced Materials 35 (19), 2370132, 2023 | | 2023 |
Author Correction: Antigen presentation by cardiac fibroblasts promotes cardiac dysfunction N Ngwenyama, K Kaur, D Bugg, B Theall, M Aronovitz, R Berland, ... Nature cardiovascular research 1 (12), 1230, 2022 | | 2022 |
Fibroblast State Reversal By MBNL1-Dependent Transcriptome Modification Regulates Cardiac Repair D Bugg, R Bretherton, K Beach, A Reese, J Gunaje, G Flint, CA DeForest, ... bioRxiv, 2021.01. 26.428279, 2021 | | 2021 |
Molecular and Spatial Regulators of Cardiac Fibroblast Cell State and Plasticity in Myocardial Infarction Injury D Bugg University of Washington, 2021 | | 2021 |
p38 Regulates Programmed Myofibroblast Differentiation and Fibrosis D Bugg, N Ghearing, LE Dorn, MA Sargent, A Gunajea, P Kim, K Otsu, ... Circulation Research 121 (suppl_1), A264-A264, 2017 | | 2017 |
Cardiac Fibrosis Induced by Mkk6-p38 Activation Alters Myocardial Stiffness and Myofilament Function F Moussavi-Harami, MV Razumova, JM Klaiman, D Bugg, M Regnier, ... Circulation Research 121 (suppl_1), A69-A69, 2017 | | 2017 |
Cell Type-specific Fibroblast Growth Factor Receptors That are Regulated in Human Heart Disease AK Peter, DN Bugg, CD Ozeroff, M Chonchol, AV Ambardekar, R Kakkar, ... Circulation Research 119 (suppl_1), A382-A382, 2016 | | 2016 |