Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potential I Batinić-Haberle, JS Rebouças, I Spasojević Antioxidants & redox signaling 13 (6), 877-918, 2010 | 592 | 2010 |
Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two different models of oxidative stress … I Batinić-Haberle, S Cuzzocrea, JS Rebouças, G Ferrer-Sueta, E Mazzon, ... Free radical biology & medicine 46 (2), 192, 2009 | 165 | 2009 |
Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics I Batinic-Haberle, Z Rajic, A Tovmasyan, JS Reboucas, X Ye, KW Leong, ... Free Radical Biology and Medicine 51 (5), 1035-1053, 2011 | 157 | 2011 |
Early and late administration of MnTE-2-PyP5+ in mitigation and treatment of radiation-induced lung damage B Gauter-Fleckenstein, K Fleckenstein, K Owzar, C Jiang, JS Rebouças, ... Free Radical Biology and Medicine 48 (8), 1034-1043, 2010 | 132 | 2010 |
Design and synthesis of manganese porphyrins with tailored lipophilicity: investigation of redox properties and superoxide dismutase activity D Lahaye, K Muthukumaran, CH Hung, D Gryko, JS Rebouças, ... Bioorganic & medicinal chemistry 15 (22), 7066-7086, 2007 | 122 | 2007 |
Pure manganese (III) 5, 10, 15, 20-tetrakis (4-benzoic acid) porphyrin (MnTBAP) is not a superoxide dismutase mimic in aqueous systems: a case of structure–activity … JS Rebouças, I Spasojević, I Batinić-Haberle JBIC Journal of Biological Inorganic Chemistry 13, 289-302, 2008 | 107 | 2008 |
Electrostatic Contribution in the Catalysis of O 2· _ Dismutation by Superoxide Dismutase Mimics: MnIIITE-2-PyP5+ VERSUSMnIIIBr8T-2-PyP+ I Spasojevic, I Batinic-Haberle, JS Rebouças, YM Idemori, I Fridovich Journal of Biological Chemistry 278 (9), 6831-6837, 2003 | 94 | 2003 |
A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics A Tovmasyan, CGC Maia, T Weitner, S Carballal, RS Sampaio, D Lieb, ... Free Radical Biology and Medicine 86, 308-321, 2015 | 92 | 2015 |
Pharmacokinetics of the potent redox-modulating manganese porphyrin, MnTE-2-PyP5+, in plasma and major organs of B6C3F1 mice I Spasojević, Y Chen, TJ Noel, P Fan, L Zhang, JS Rebouças, DKS Clair, ... Free Radical Biology and Medicine 45 (7), 943-949, 2008 | 81 | 2008 |
Anticancer therapeutic potential of Mn porphyrin/ascorbate system A Tovmasyan, RS Sampaio, MK Boss, JC Bueno-Janice, BH Bader, ... Free Radical Biology and Medicine 89, 1231-1247, 2015 | 77 | 2015 |
Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia–telangiectasia cells JM Pollard, JS Reboucas, A Durazo, I Kos, F Fike, M Panni, EB Gralla, ... Free Radical Biology and Medicine 47 (3), 250-260, 2009 | 77 | 2009 |
Partially and fully β-brominated Mn-porphyrins in P450 biomimetic systems: effects of the degree of bromination on electrochemical and catalytic properties E Do Nascimento, GF Silva, FA Caetano, MAM Fernandes, DC da Silva, ... Journal of inorganic biochemistry 99 (5), 1193-1204, 2005 | 77 | 2005 |
Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn (III) N-alkylpyridylporphyrins I Kos, JS Rebouças, G DeFreitas-Silva, D Salvemini, Z Vujaskovic, ... Free Radical Biology and Medicine 47 (1), 72-78, 2009 | 76 | 2009 |
Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology A Tovmasyan, T Weitner, H Sheng, MM Lu, Z Rajic, DS Warner, ... Inorganic chemistry 52 (10), 5677-5691, 2013 | 75 | 2013 |
Impact of electrostatics in redox modulation of oxidative stress by Mn porphyrins: protection of SOD-deficient Escherichia coli via alternative mechanism where Mn porphyrin … JS Rebouças, G DeFreitas-Silva, I Spasojević, YM Idemori, L Benov, ... Free Radical Biology and Medicine 45 (2), 201-210, 2008 | 71 | 2008 |
Simple biological systems for assessing the activity of superoxide dismutase mimics A Tovmasyan, JS Reboucas, L Benov Antioxidants & Redox Signaling 20 (15), 2416-2436, 2014 | 68 | 2014 |
Comprehensive pharmacokinetic studies and oral bioavailability of two Mn porphyrin-based SOD mimics, MnTE-2-PyP5+ and MnTnHex-2-PyP5+ T Weitner, I Kos, H Sheng, A Tovmasyan, JS Reboucas, P Fan, ... Free Radical Biology and Medicine 58, 73-80, 2013 | 63 | 2013 |
Quality of potent Mn porphyrin-based SOD mimics and peroxynitrite scavengers for pre-clinical mechanistic/therapeutic purposes JS Rebouças, I Spasojević, I Batinić-Haberle Journal of pharmaceutical and biomedical analysis 48 (3), 1046-1049, 2008 | 63 | 2008 |
SOD-like activity of Mn (II) β-octabromo-meso-tetrakis (N-methylpyridinium-3-yl) porphyrin equals that of the enzyme itself G DeFreitas-Silva, JS Rebouças, I Spasojević, L Benov, YM Idemori, ... Archives of biochemistry and biophysics 477 (1), 105-112, 2008 | 63 | 2008 |
Spectral, electrochemical, and catalytic properties of a homologous series of manganese porphyrins as cytochrome P450 model: the effect of the degree of β-bromination DC da Silva, G DeFreitas-Silva, E do Nascimento, JS Rebouças, ... Journal of inorganic biochemistry 102 (10), 1932-1941, 2008 | 61 | 2008 |