| Precision is essential for efficient catalysis in an evolved Kemp eliminase R Blomberg, H Kries, DM Pinkas, PRE Mittl, MG Grütter, HK Privett, ... Nature 503 (7476), 418-421, 2013 | 348 | 2013 |
| De novo enzymes by computational design H Kries, R Blomberg, D Hilvert Current opinion in chemical biology 17 (2), 221-228, 2013 | 293 | 2013 |
| Reprogramming nonribosomal peptide synthetases for “clickable” amino acids H Kries, R Wachtel, A Pabst, B Wanner, D Niquille, D Hilvert Angewandte Chemie 126 (38), 10269-10272, 2014 | 136 | 2014 |
| A subdomain swap strategy for reengineering nonribosomal peptides H Kries, DL Niquille, D Hilvert Chemistry & biology 22 (5), 640-648, 2015 | 123 | 2015 |
| Nonribosomal biosynthesis of backbone-modified peptides DL Niquille, DA Hansen, T Mori, D Fercher, H Kries, D Hilvert Nature chemistry 10 (3), 282-287, 2018 | 112 | 2018 |
| Identification and characterization of the iridoid synthase involved in oleuropein biosynthesis in olive (Olea europaea) fruits F Alagna, F Geu-Flores, H Kries, F Panara, L Baldoni, SE O'Connor, ... Journal of Biological Chemistry 291 (11), 5542-5554, 2016 | 90 | 2016 |
| The effect of phosphomonoesterases on the oxygen isotope composition of phosphate C von Sperber, H Kries, F Tamburini, SM Bernasconi, E Frossard Geochimica et Cosmochimica Acta 125, 519-527, 2014 | 88 | 2014 |
| Structural determinants of reductive terpene cyclization in iridoid biosynthesis H Kries, L Caputi, CEM Stevenson, MO Kamileen, NH Sherden, ... Nature chemical biology 12 (1), 6-8, 2016 | 74 | 2016 |
| Adenylation domains in nonribosomal peptide engineering A Stanišić, H Kries ChemBioChem 20 (11), 1347-1356, 2019 | 57 | 2019 |
| Biosynthetic engineering of nonribosomal peptide synthetases H Kries Journal of Peptide Science 22 (9), 564-570, 2016 | 53 | 2016 |
| Emergence of a negative activation heat capacity during evolution of a designed enzyme HA Bunzel, H Kries, L Marchetti, C Zeymer, PRE Mittl, AJ Mulholland, ... Journal of the American Chemical Society 141 (30), 11745-11748, 2019 | 46 | 2019 |
| Site-Specific Polymer Conjugation Stabilizes Therapeutic Enzymes in the Gastrointestinal Tract. JD Schulz, M Patt, S Basler, H Kries, D Hilvert, MA Gauthier, JC Leroux Advanced Materials (Deerfield Beach, Fla.) 28 (7), 1455-1460, 2015 | 40 | 2015 |
| Biocatalytic strategies towards [4+ 2] cycloadditions BR Lichman, SE O'Connor, H Kries Chemistry–A European Journal 25 (28), 6864-6877, 2019 | 36 | 2019 |
| Inverted stereocontrol of iridoid synthase in snapdragon H Kries, F Kellner, MO Kamileen, SE O'Connor Journal of Biological Chemistry 292 (35), 14659-14667, 2017 | 33 | 2017 |
| Biocatalysts from alkaloid producing plants H Kries, SE O’Connor Current Opinion in Chemical Biology 31, 22-30, 2016 | 33 | 2016 |
| HAMA: a multiplexed LC-MS/MS assay for specificity profiling of adenylate-forming enzymes A Stanišić, A Hüsken, H Kries Chemical science 10 (44), 10395-10399, 2019 | 30 | 2019 |
| Design, selection, and characterization of a split chorismate mutase MM Müller, H Kries, E Csuhai, P Kast, D Hilvert Protein science 19 (5), 1000-1010, 2010 | 30 | 2010 |
| Sulfonium Acids Loaded onto an Unusual Thiotemplate Assembly Line Construct the Cyclopropanol Warhead of a Burkholderia Virulence Factor F Trottmann, K Ishida, J Franke, A Stanišić, M Ishida‐Ito, H Kries, ... Angewandte Chemie 132 (32), 13613-13617, 2020 | 29 | 2020 |
| Engineering DNA-templated nonribosomal peptide synthesis HM Huang, P Stephan, H Kries Cell Chemical Biology 28 (2), 221-227. e7, 2021 | 27 | 2021 |
| Structure elucidation of the syringafactin lipopeptides provides insight in the evolution of nonribosomal peptide synthetases S Götze, J Arp, G Lackner, S Zhang, H Kries, M Klapper, M García-Altares, ... Chemical Science 10 (48), 10979-10990, 2019 | 26 | 2019 |
David Laurent NiquilleMIT在 mit.edu 的电子邮件经过验证
