An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity W Guo, Y Chen, X Zhou, A Kar, P Ray, X Chen, EJ Rao, M Yang, H Ye, ... Nature structural & molecular biology 18 (7), 822-830, 2011 | 340 | 2011 |
A Drosophila model for TDP-43 proteinopathy Y Li, P Ray, EJ Rao, C Shi, W Guo, X Chen, EA Woodruff III, K Fushimi, ... Proceedings of the National Academy of Sciences 107 (7), 3169-3174, 2010 | 339 | 2010 |
Multiple autism-linked genes mediate synapse elimination via proteasomal degradation of a synaptic scaffold PSD-95 NP Tsai, JR Wilkerson, W Guo, MA Maksimova, GN DeMartino, ... Cell 151 (7), 1581-1594, 2012 | 306 | 2012 |
Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome JA Ronesi, KA Collins, SA Hays, NP Tsai, W Guo, SG Birnbaum, JH Hu, ... Nature neuroscience 15 (3), 431-440, 2012 | 279 | 2012 |
Increased metabotropic glutamate receptor 5 signaling underlies obsessive-compulsive disorder-like behavioral and striatal circuit abnormalities in mice KK Ade, Y Wan, HC Hamann, JK O’Hare, W Guo, A Quian, S Kumar, ... Biological psychiatry 80 (7), 522-533, 2016 | 81 | 2016 |
Selective Disruption of Metabotropic Glutamate Receptor 5-Homer Interactions Mimics Phenotypes of Fragile X Syndrome in Mice Weirui Guo, Gemma Molinaro, Katie A. Collins, Seth A. Hays, Richard Paylor ... The Journal of Neuroscience 36 (7), 2131-2147, 2016 | 61 | 2016 |
Elevated CaMKIIα and hyperphosphorylation of Homer mediate circuit dysfunction in a fragile X syndrome mouse model W Guo, L Ceolin, KA Collins, J Perroy, KM Huber Cell reports 13 (10), 2297-2311, 2015 | 56 | 2015 |
FMRP-dependent Mdm2 dephosphorylation is required for MEF2-induced synapse elimination NP Tsai, JR Wilkerson, W Guo, KM Huber Human molecular genetics 26 (2), 293-304, 2017 | 32 | 2017 |
Candidate Mycobacterium tuberculosis genes targeted by human microRNAs WR Guo, JT Li, X Pan, L Wei, JY Wu Protein & cell 1 (5), 419, 2010 | 24 | 2010 |
siRNA 诱导的 DNA 甲基化与肿瘤的发生 郭维锐, 殷勤伟 生物化学与生物物理进展 33 (1), 10-16, 2006 | 7 | 2006 |
targeted by human microRNAs WR Guo, JT Li, X Pan, L Wei, JY Wu | | 2010 |