Functional antagonists at the NMDA receptor complex exhibit antidepressant actions R Trullas, P Skolnick European journal of pharmacology 185 (1), 1-10, 1990 | 947 | 1990 |
Differences in fear motivated behaviors among inbred mouse strains R Trullas, P Skolnick Psychopharmacology 111, 323-331, 1993 | 533 | 1993 |
Glutamate-based antidepressants: 20 years on P Skolnick, P Popik, R Trullas Trends in pharmacological sciences 30 (11), 563-569, 2009 | 462 | 2009 |
Amyloid β oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors E Alberdi, MV Sánchez-Gómez, F Cavaliere, A Pérez-Samartín, ... Cell calcium 47 (3), 264-272, 2010 | 457 | 2010 |
Adaptation of N-methyl-D-aspartate (NMDA) receptors following antidepressant treatment: implications for the pharmacotherapy of depression P Skolnick, RT Layer, P Popik, G Nowak, IA Paul, R Trullas Pharmacopsychiatry 29 (01), 23-26, 1996 | 444 | 1996 |
Adaptive changes in the N-methyl-D-aspartate receptor complex after chronic treatment with imipramine and 1-aminocyclopropanecarboxylic acid G Nowak, R Trullas, RT Layer, P Skolnick, IA Paul Journal of Pharmacology and Experimental Therapeutics 265 (3), 1380-1386, 1993 | 261 | 1993 |
Low cerebrospinal fluid concentration of mitochondrial DNA in preclinical Alzheimer disease P Podlesniy, J Figueiro‐Silva, A Llado, A Antonell, R Sanchez‐Valle, ... Annals of neurology 74 (5), 655-668, 2013 | 214 | 2013 |
Protection by imidazol (ine) drugs and agmatine of glutamate‐induced neurotoxicity in cultured cerebellar granule cells through blockade of NMDA receptor G Olmos, N DeGregorio‐Rocasolano, MP Regalado, T Gasull, ... British journal of pharmacology 127 (6), 1317-1326, 1999 | 200 | 1999 |
Current perspectives on the development of non-biogenic amine-based antidepressants P Skolnick, B Legutko, X Li, FP Bymaster Pharmacological research 43 (5), 411-422, 2001 | 167 | 2001 |
Associative learning and CA3–CA1 synaptic plasticity are impaired in D1R null, Drd1a−/− mice and in hippocampal siRNA silenced Drd1a mice O Ortiz, JM Delgado-García, I Espadas, A Bahí, R Trullas, JL Dreyer, ... Journal of Neuroscience 30 (37), 12288-12300, 2010 | 155 | 2010 |
Soluble oligomers of amyloid-β peptide disrupt membrane trafficking of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor contributing to early synapse dysfunction AJ Minano-Molina, J España, E Martín, B Barneda-Zahonero, R Fado, ... Journal of Biological Chemistry 286 (31), 27311-27321, 2011 | 124 | 2011 |
Neuronal pentraxin 1 contributes to the neuronal damage evoked by amyloid-β and is overexpressed in dystrophic neurites in Alzheimer's brain MA Abad, M Enguita, N DeGregorio-Rocasolano, I Ferrer, R Trullas Journal of Neuroscience 26 (49), 12735-12747, 2006 | 124 | 2006 |
1-Aminocyclopropanecarboxylates exhibit antidepressant and anxiolytic actions in animal models R Trullas, T Folio, A Young, R Miller, K Boje, P Skolnick European journal of pharmacology 203 (3), 379-385, 1991 | 122 | 1991 |
Anxiolytic properties of 1-aminocyclopropanecarboxylic acid, a ligand at strychnine-insensitive glycine receptors R Trullas, B Jackson, P Skolnick Pharmacology Biochemistry and Behavior 34 (2), 313-316, 1989 | 118 | 1989 |
The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2 G López-Doménech, R Serrat, S Mirra, S D'aniello, I Somorjai, A Abad, ... Nature communications 3 (1), 814, 2012 | 110 | 2012 |
Treatment of mood disorders with functional antagonists of the glycine/nmda receptor complex R Trullas, P Skolnick US Patent 5,086,072, 1992 | 103 | 1992 |
Time course of changes in serotonin and noradrenaline in rat brain after predictable or unpredictable shock A Adell, R Trullas, E Gelpi Brain research 459 (1), 54-59, 1988 | 101 | 1988 |
Rat pup isolation calls are reduced by functional antagonists of the NMDA receptor JT Winslow, TR Insel, R Trullas, P Skolnick European journal of pharmacology 190 (1-2), 11-21, 1990 | 100 | 1990 |
Down-regulation of cortical β-adrenoceptors by chronic treatment with functional NMDA antagonists IA Paul, R Trullas, P Skolnick, G Nowak Psychopharmacology 106, 285-287, 1992 | 93 | 1992 |
Chronic treatment with 1-aminocyclopropanecarboxylic acid desensitizes behavioral responses to compounds acting at the N-methyl-d-aspartate receptor complex P Skolnick, R Miller, A Young, K Boje, R Trullas Psychopharmacology 107, 489-496, 1992 | 91 | 1992 |