Somatic coding mutations in human induced pluripotent stem cells A Gore, Z Li, HL Fung, JE Young, S Agarwal, J Antosiewicz-Bourget, ... Nature 471 (7336), 63-67, 2011 | 1465 | 2011 |
Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines C Bock, E Kiskinis, G Verstappen, H Gu, G Boulting, ZD Smith, M Ziller, ... Cell 144 (3), 439-452, 2011 | 1152 | 2011 |
Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease LF Burbulla, P Song, JR Mazzulli, E Zampese, YC Wong, S Jeon, ... Science 357 (6357), 1255-1261, 2017 | 753 | 2017 |
Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations NH Alami, RB Smith, MA Carrasco, LA Williams, CS Winborn, SSW Han, ... Neuron 81 (3), 536-543, 2014 | 712 | 2014 |
Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons BJ Wainger, E Kiskinis, C Mellin, O Wiskow, SSW Han, J Sandoe, ... Cell reports 7 (1), 1-11, 2014 | 708 | 2014 |
A functionally characterized test set of human induced pluripotent stem cells GL Boulting, E Kiskinis, GF Croft, MW Amoroso, DH Oakley, BJ Wainger, ... Nature biotechnology 29 (3), 279-286, 2011 | 587 | 2011 |
Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1 E Kiskinis, J Sandoe, LA Williams, GL Boulting, R Moccia, BJ Wainger, ... Cell stem cell 14 (6), 781-795, 2014 | 513 | 2014 |
Progress toward the clinical application of patient-specific pluripotent stem cells E Kiskinis, K Eggan The Journal of clinical investigation 120 (1), 51-59, 2010 | 434 | 2010 |
Erosion of dosage compensation impacts human iPSC disease modeling S Mekhoubad, C Bock, AS De Boer, E Kiskinis, A Meissner, K Eggan Cell stem cell 10 (5), 595-609, 2012 | 380 | 2012 |
Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes AM Powelka, A Seth, JV Virbasius, E Kiskinis, SM Nicoloro, A Guilherme, ... The Journal of clinical investigation 116 (1), 125-136, 2006 | 297 | 2006 |
Progress in understanding and treating SCN2A-mediated disorders SJ Sanders, AJ Campbell, JR Cottrell, RS Moller, FF Wagner, ... Trends in neurosciences 41 (7), 442-456, 2018 | 272 | 2018 |
RIP140-targeted repression of gene expression in adipocytes M Christian, E Kiskinis, D Debevec, G Leonardsson, R White, MG Parker Molecular and cellular biology, 2005 | 222 | 2005 |
Bioactive scaffolds with enhanced supramolecular motion promote recovery from spinal cord injury Z Álvarez, AN Kolberg-Edelbrock, IR Sasselli, JA Ortega, R Qiu, ... Science 374 (6569), 848-856, 2021 | 216 | 2021 |
A functional interaction between RIP140 and PGC-1α regulates the expression of the lipid droplet protein CIDEA M Hallberg, DL Morganstein, E Kiskinis, K Shah, A Kralli, SM Dilworth, ... Molecular and cellular biology 28 (22), 6785-6795, 2008 | 203 | 2008 |
Use of the alkaline comet assay for industrial genotoxicity screening: comparative investigation with the micronucleus test A Hartmann, A Elhajouji, E Kiskinis, F Poetter, HJ Martus, A Fjällman, ... Food and chemical toxicology 39 (8), 843-858, 2001 | 136 | 2001 |
RIP140 directs histone and DNA methylation to silence Ucp1 expression in white adipocytes E Kiskinis, M Hallberg, M Christian, M Olofsson, SM Dilworth, R White, ... The EMBO journal 26 (23), 4831-4840, 2007 | 123 | 2007 |
The SWI/SNF chromatin remodeling subunit BAF57 is a critical regulator of estrogen receptor function in breast cancer cells JM García-Pedrero, E Kiskinis, MG Parker, B Belandia Journal of Biological Chemistry 281 (32), 22656-22664, 2006 | 117 | 2006 |
Effect of ezogabine on cortical and spinal motor neuron excitability in amyotrophic lateral sclerosis: a randomized clinical trial BJ Wainger, EA Macklin, S Vucic, CE McIlduff, S Paganoni, NJ Maragakis, ... JAMA neurology 78 (2), 186-196, 2021 | 111 | 2021 |
High throughput Comet assay using 96-well plates E Kiskinis, W Suter, A Hartmann Mutagenesis 17 (1), 37-43, 2002 | 97 | 2002 |
TETs compete with DNMT3 activity in pluripotent cells at thousands of methylated somatic enhancers J Charlton, EJ Jung, AL Mattei, N Bailly, J Liao, EJ Martin, P Giesselmann, ... Nature genetics 52 (8), 819-827, 2020 | 96 | 2020 |