Proline cis-trans isomerization controls autoinhibition of a signaling protein P Sarkar, C Reichman, T Saleh, RB Birge, CG Kalodimos Molecular cell 25 (3), 413-426, 2007 | 226 | 2007 |
Conformational states dynamically populated by a kinase determine its function T Xie, T Saleh, P Rossi, CG Kalodimos Science 370 (6513), eabc2754, 2020 | 170 | 2020 |
Structural basis for regulation of the Crk signaling protein by a proline switch P Sarkar, T Saleh, SR Tzeng, RB Birge, CG Kalodimos Nature chemical biology 7 (1), 51-57, 2011 | 97 | 2011 |
Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII W Jankowski, T Saleh, MT Pai, G Sriram, RB Birge, CG Kalodimos Nature chemical biology 8 (6), 590-596, 2012 | 71 | 2012 |
Atomic view of the energy landscape in the allosteric regulation of Abl kinase T Saleh, P Rossi, CG Kalodimos Nature structural & molecular biology 24 (11), 893-901, 2017 | 59 | 2017 |
Automatic methyl assignment in large proteins by the MAGIC algorithm YR Monneau, P Rossi, A Bhaumik, C Huang, Y Jiang, T Saleh, T Xie, ... Journal of biomolecular NMR 69, 215-227, 2017 | 50 | 2017 |
Enzymes at work are enzymes in motion T Saleh, CG Kalodimos Science 355 (6322), 247-248, 2017 | 45 | 2017 |
Cyclophilin A promotes cell migration via the Abl-Crk signaling pathway T Saleh, W Jankowski, G Sriram, P Rossi, S Shah, KB Lee, LA Cruz, ... Nature chemical biology 12 (2), 117-123, 2016 | 43 | 2016 |
Phosphorylation of Crk on tyrosine 251 in the RT loop of the SH3C domain promotes Abl kinase transactivation G Sriram, C Reichman, A Tunceroglu, N Kaushal, T Saleh, K Machida, ... Oncogene 30 (46), 4645-4655, 2011 | 38 | 2011 |
Enhancing the sensitivity of multidimensional NMR experiments by using triply-compensated π pulses Y Xia, P Rossi, MV Subrahmanian, C Huang, T Saleh, C Olivieri, ... Journal of biomolecular NMR 69, 237-243, 2017 | 19 | 2017 |
Cyclophilin A inhibitor debio-025 targets Crk, reduces metastasis, and induces tumor immunogenicity in breast cancer V Davra, T Saleh, K Geng, S Kimani, D Mehta, C Kasikara, B Smith, ... Molecular cancer research 18 (8), 1189-1201, 2020 | 13 | 2020 |
Iterative tyrosine phosphorylation controls non-canonical domain utilization in Crk G Sriram, W Jankowski, C Kasikara, C Reichman, T Saleh, KQ Nguyen, ... Oncogene 34 (32), 4260-4269, 2015 | 11 | 2015 |
Imatinib can act as an Allosteric Activator of Abl Kinase T Xie, T Saleh, P Rossi, D Miller, CG Kalodimos Journal of molecular biology 434 (2), 167349, 2022 | 10 | 2022 |
Conformational states dynamically populated by a kinase determine its function, Science, 370, eabc2754 T Xie, T Saleh, P Rossi, CG Kalodimos | 9 | 2020 |
Progress toward automated methyl assignments for methyl-TROSY applications MC Clay, T Saleh, S Kamatham, P Rossi, CG Kalodimos Structure 30 (1), 69-79. e2, 2022 | 8 | 2022 |
An Allosteric Mechanism of Abl Kinase Activation and Catalysis T Saleh Biophysical Journal 114 (3), 422a, 2018 | | 2018 |
Gleevec Can Act as an Allosteric Activator of ABL Kinase T Xie, T Saleh, CG Kalodimos Biophysical Journal 114 (3), 229a, 2018 | | 2018 |
Structural analysis of adaptor protein CrkL and the role of CypA in Bcr-Abl mediated signaling T Saleh Rutgers University-Graduate School-New Brunswick, 2012 | | 2012 |