Pro-fibrotic phenotype of bone marrow stromal cells in Modic type 1 changes I Heggli, S Epprecht, A Juengel, R Schuepbach, NA Farshad-Amacker, ... European Cells and Materials (ECM) 41, 648-667, 2021 | 9 | 2021 |
Low back pain patients with Modic type 1 changes exhibit distinct bacterial and non-bacterial subtypes I Heggli, T Mengis, CJ Laux, L Opitz, N Herger, D Menghini, ... Osteoarthritis and Cartilage Open 6 (1), 100434, 2024 | 7 | 2024 |
Role of C‐reactive protein in the bone marrow of Modic type 1 changes S Dudli, I Heggli, CJ Laux, JM Spirig, F Wanivenhaus, M Betz, C Germann, ... Journal of Orthopaedic Research® 41 (5), 1115-1122, 2023 | 7 | 2023 |
Modic type 2 changes are fibroinflammatory changes with complement system involvement adjacent to degenerated vertebral endplates I Heggli, CJ Laux, T Mengis, A Karol, F Cornaz, N Herger, B Aradi‐Vegh, ... JOR spine 6 (1), e1237, 2023 | 6 | 2023 |
Mutant SF3B1 promotes malignancy in PDAC P Simmler, EI Ioannidi, T Mengis, KF Marquart, S Asawa, K Van-Lehmann, ... Elife 12, e80683, 2023 | 2 | 2023 |
Impacts of priming on distinct immunosuppressive mechanisms of mesenchymal stromal cells under translationally relevant conditions N Herger, I Heggli, T Mengis, J Devan, L Arpesella, F Brunner, O Distler, ... Stem Cell Research & Therapy 15 (1), 65, 2024 | 1 | 2024 |
AB1398 STROMAL CELLS IN MODIC TYPE 1 CHANGE BONE MARROW PROMOTE NEURITE OUTGROWTH T Mengis, I Heggli, N Herger, B Aradi-Vegh, F Brunner, M Farshad, ... Annals of the Rheumatic Diseases 82 (Suppl 1), 1928-1928, 2023 | 1 | 2023 |
POS0416 distinct degeneration mechanisms in intervertebral discs adjacent to Modic changes T Mengis, I Heggli, N Herger, B Aradi-Vegh, B Roschitzki, J Grossmann, ... Annals of the Rheumatic Diseases 82 (Suppl 1), 463-464, 2023 | 1 | 2023 |
POS0417 ACTIVATED NEUTROPHILS DEGRADE CARTILAGE ENDPLATES I Heggli, M Habib, J Scheer, N Herger, T Mengis, C Laux, F Wanivenhaus, ... Annals of the Rheumatic Diseases 82 (Suppl 1), 464-465, 2023 | 1 | 2023 |
Fgf2 overrides key pro-fibrotic features of bone marrow stromal cells isolated from modic type 1 change patients I Heggli, U Blache, N Herger, T Mengis, PK Jaeger, R Schuepbach, ... European Cells & Materials 44, 101-114, 2022 | 1 | 2022 |
The Role of Intervertebral Disc Cartilage Catabolites in Modic Type 1 Changes T Mengis University of Zurich, 2024 | | 2024 |
POS0343 HIGHER ABUNDANCE OF HTRA1 GENERATED FRAGMENTS IN THE DEGRADOME OF MODIC TYPE 1 DISCS T Mengis, B Roschitzki, I Heggli, N Herger, M Farshad, O Distler, S Dudli Annals of the Rheumatic Diseases 83 (Suppl 1), 353-354, 2024 | | 2024 |
POS0526 ACCUMULATION OF STRESS-INDUCED MOLECULES RECOGNIZING T CELLS IN MODIC TYPE 1 CHANGES J Devan, S Dudli, N Herger, T Mengis, I Heggli, MPV Valdes, M Farshad, ... Annals of the Rheumatic Diseases 83 (Suppl 1), 1106-1107, 2024 | | 2024 |
Intervertebral disc microbiome in Modic changes: Lack of result replication underscores the need for a consensus in low‐biomass microbiome analysis T Mengis, N Zajac, L Bernhard, I Heggli, N Herger, J Devan, R Marcus, ... JOR spine 7 (2), e1330, 2024 | | 2024 |
Expression of toll-like receptors in cartilage endplates cells: a role of toll-like receptor 2 in pro-inflammatory and-catabolic gene expression T Mengis, L Bernhard, N Herger, I Heggli, J Devan, R Marcus, C Laux, ... | | 2024 |
Do Cells of Intervertebral Discs with type 1 Modic Change on MRI show a History of Impaired Spinal Fusion? B Gantenbein, AE Oberli, T Mengis, HM Bonel, CE Albers, O Hausmann, ... | | 2024 |
Bone marrow stromal cells in Modic type 1 changes promote neurite outgrowth T Mengis, N Herger, I Heggli, J Devan, JM Spirig, CJ Laux, F Brunner, ... Frontiers in Cell and Developmental Biology 11, 1286280, 2023 | | 2023 |
AB1394 INTRADISCAL CUTIBACTERIUM ACNES DECIDE ON INNATE AND ADAPTIVE IMMUNE PATHWAYS IN MODIC TYPE 1 CHANGES I Heggli, T Mengis, L Opitz, N Herger, C Laux, F Wanivenhaus, JM Spirig, ... Annals of the Rheumatic Diseases 82 (Suppl 1), 1926-1926, 2023 | | 2023 |
Mutant SF3B1 promotes PDAC malignancy through TGF-β resistance PT Simmler, T Mengis, KV Lehmann, A Kahles, T Thomas, G Rätsch, ... bioRxiv, 2022.06. 16.496393, 2022 | | 2022 |
THU0451 CELL-MATRIX ADHESION OF BONE MARROW STROMAL CELLS IN MODIC TYPE 1 CHANGES IS INCREASED AND RELATES TO INCREASED EXPRESSION OF INTEGRIN Β1 I Heggli, S Epprecht, T Mengis, A Juengel, M Betz, J Spirig, ... Annals of the Rheumatic Diseases 79 (Suppl 1), 462-462, 2020 | | 2020 |