Co-regulatory networks of human serum proteins link genetics to disease V Emilsson, M Ilkov, JR Lamb, N Finkel, EF Gudmundsson, R Pitts, ... Science 361 (6404), 769-773, 2018 | 457 | 2018 |
Targeting BCAA catabolism to treat obesity-associated insulin resistance M Zhou, J Shao, CY Wu, L Shu, W Dong, Y Liu, M Chen, RM Wynn, ... Diabetes 68 (9), 1730-1746, 2019 | 239 | 2019 |
Exposure to the BPA-substitute bisphenol S causes unique alterations of germline function Y Chen, L Shu, Z Qiu, DY Lee, SJ Settle, S Que Hee, D Telesca, X Yang, ... PLoS genetics 12 (7), e1006223, 2016 | 112 | 2016 |
Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems L Shu, Y Zhao, Z Kurt, SG Byars, T Tukiainen, J Kettunen, LD Orozco, ... BMC genomics 17, 1-16, 2016 | 106 | 2016 |
Shared genetic regulatory networks for cardiovascular disease and type 2 diabetes in multiple populations of diverse ethnicities in the United States L Shu, KHK Chan, G Zhang, T Huan, Z Kurt, Y Zhao, V Codoni, ... PLoS genetics 13 (9), e1007040, 2017 | 87 | 2017 |
Mergeomics: a web server for identifying pathological pathways, networks, and key regulators via multidimensional data integration D Arneson, A Bhattacharya, L Shu, VP Mäkinen, X Yang BMC genomics 17, 1-9, 2016 | 64 | 2016 |
Multi-omics integration reveals molecular networks and regulators of psoriasis Y Zhao, D Jhamb, L Shu, D Arneson, DK Rajpal, X Yang BMC systems biology 13, 1-14, 2019 | 44 | 2019 |
Prenatal bisphenol A exposure in mice induces multitissue multiomics disruptions linking to cardiometabolic disorders L Shu, Q Meng, G Diamante, B Tsai, YW Chen, A Mikhail, H Luk, B Ritz, ... Endocrinology 160 (2), 409-429, 2019 | 44 | 2019 |
Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes AS Axelsson, T Mahdi, HA Nenonen, T Singh, S Hänzelmann, A Wendt, ... Nature communications 8 (1), 15652, 2017 | 40 | 2017 |
Translating GWAS findings to novel therapeutic targets for coronary artery disease L Shu, M Blencowe, X Yang Frontiers in cardiovascular medicine 5, 56, 2018 | 39 | 2018 |
Multidimensional integrative genomics approaches to dissecting cardiovascular disease D Arneson, L Shu, B Tsai, R Barrere-Cain, C Sun, X Yang Frontiers in cardiovascular medicine 4, 8, 2017 | 34 | 2017 |
Differential metabolic and multi-tissue transcriptomic responses to fructose consumption among genetically diverse mice G Zhang, HR Byun, Z Ying, M Blencowe, Y Zhao, J Hong, L Shu, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (1), 165569, 2020 | 28 | 2020 |
Long-term effect of dietary fibre intake on glycosylated haemoglobin A1c level and glycaemic control status among Chinese patients with type 2 diabetes mellitus L Yang, L Shu, J Jiang, H Qiu, G Zhao, Y Zhou, Q Jiang, Q Sun, G Qin, ... Public health nutrition 17 (8), 1858-1864, 2014 | 26 | 2014 |
Oral 15-Hydroxyeicosatetraenoic Acid Induces Pulmonary Hypertension in Mice by Triggering T Cell–Dependent Endothelial Cell Apoptosis G Ruffenach, E O’connor, M Vaillancourt, J Hong, N Cao, S Sarji, ... Hypertension 76 (3), 985-996, 2020 | 23 | 2020 |
Integrative genomics analysis unravels tissue-specific pathways, networks, and key regulators of blood pressure regulation Y Zhao, M Blencowe, X Shi, L Shu, C Levian, IS Ahn, SK Kim, T Huan, ... Frontiers in cardiovascular medicine 6, 21, 2019 | 17 | 2019 |
BCAA catabolism drives adipogenesis via an intermediate metabolite and promotes subcutaneous adipose tissue expansion during obesity J Shao, Y Liu, X Zhang, L Shu, J Yu, S Yang, C Gao, C Wang, N Cao, ... bioRxiv, 2022.08. 18.504380, 2022 | 5 | 2022 |
Bioinformatics principles for deciphering cardiovascular diseases L Shu, D Arneson, X Yang Elsevier, 2018 | 5 | 2018 |
Mergeomics: integration of diverse genomics resources to identify pathogenic perturbations to biological systems L Shu, Y Zhao, Z Kurt, SG Byars, T Tukiainen, J Kettunen, S Ripatti, ... BioRxiv, 036012, 2016 | 5 | 2016 |
Mergeomics: Integrative Network Analysis of Omics Data L Shu, Y Zhao, Z Kurt, SG Byars, T Tukiainen, J Kettunen, LD Orozco, ... | 3 | 2017 |
Association of CDKAL1 genetic polymorphism with glycosylated hemoglobin A1clevel among non-diabetic Chinese adults JY Jiang, H Qiu, GM Zhao, Y Zhou, M Mo, L Shu J Diabetes Metab 2 (166), 2, 2011 | 3 | 2011 |