| 8-Oxo-7, 8-dihydroguanine in DNA does not constitute a barrier to transcription, but is converted into transcription-blocking damage by OGG1 N Kitsera, D Stathis, B Lühnsdorf, H Müller, T Carell, B Epe, A Khobta Nucleic acids research 39 (14), 5926-5934, 2011 | 111 | 2011 |
| Widespread transcriptional gene inactivation initiated by a repair intermediate of 8-oxoguanine J Allgayer, N Kitsera, S Bartelt, B Epe, A Khobta Nucleic acids research 44 (15), 7267-7280, 2016 | 88 | 2016 |
| Early effects of topoisomerase I inhibition on RNA polymerase II along transcribed genes in human cells A Khobta, F Ferri, L Lotito, A Montecucco, R Rossi, G Capranico Journal of molecular biology 357 (1), 127-138, 2006 | 72 | 2006 |
| Destabilized green fluorescent protein detects rapid removal of transcription blocks after genotoxic exposure N Kitsera, A Khobta, B Epe Biotechniques 43 (2), 222-227, 2007 | 65 | 2007 |
| Gene silencing induced by oxidative DNA base damage: association with local decrease of histone H4 acetylation in the promoter region A Khobta, S Anderhub, N Kitsera, B Epe Nucleic acids research 38 (13), 4285-4295, 2010 | 64 | 2010 |
| 8-Oxoguanine DNA glycosylase (Ogg1) causes a transcriptional inactivation of damaged DNA in the absence of functional Cockayne syndrome B (Csb) protein A Khobta, N Kitsera, B Speckmann, B Epe DNA repair 8 (3), 309-317, 2009 | 51 | 2009 |
| Nucleotide excision repair of abasic DNA lesions N Kitsera, M Rodriguez-Alvarez, S Emmert, T Carell, A Khobta Nucleic Acids Research 47 (16), 8537-8547, 2019 | 49 | 2019 |
| Functional impacts of 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxycytosine at a single hemi-modified CpG dinucleotide in a gene promoter N Kitsera, J Allgayer, E Parsa, N Geier, M Rossa, T Carell, A Khobta Nucleic acids research 45 (19), 11033-11042, 2017 | 48 | 2017 |
| Modulation of base excision repair of 8-oxoguanine by the nucleotide sequence J Allgayer, N Kitsera, C von der Lippen, B Epe, A Khobta Nucleic acids research 41 (18), 8559-8571, 2013 | 47 | 2013 |
| Interactions between DNA damage, repair, and transcription A Khobta, B Epe Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 736 (1 …, 2012 | 47 | 2012 |
| Repair of oxidatively generated DNA damage in Cockayne syndrome A Khobta, B Epe Mechanisms of ageing and development 134 (5-6), 253-260, 2013 | 32 | 2013 |
| G1 cell-cycle arrest and apoptosis by histone deacetylase inhibition in MLL-AF9 acute myeloid leukemia cells is p21 dependent and MLL-AF9 independent R Tonelli, R Sartini, R Fronza, F Freccero, M Franzoni, D Dongiovanni, ... Leukemia 20 (7), 1307-1310, 2006 | 29 | 2006 |
| Excision of uracil from transcribed DNA negatively affects gene expression B Lühnsdorf, B Epe, A Khobta Journal of Biological Chemistry 289 (32), 22008-22018, 2014 | 28 | 2014 |
| Generation of reporter plasmids containing defined base modifications in the DNA strand of choice B Lühnsdorf, N Kitsera, D Warken, T Lingg, B Epe, A Khobta Analytical biochemistry 425 (1), 47-53, 2012 | 27 | 2012 |
| New Techniques to Assess In Vitro Release of siRNA from Nanoscale Polyplexes B Krieg, M Hirsch, E Scholz, L Nuhn, I Tabujew, H Bauer, S Decker, ... Pharmaceutical Research 32, 1957-1974, 2015 | 25 | 2015 |
| Cockayne syndrome: varied requirement of transcription-coupled nucleotide excision repair for the removal of three structurally different adducts from transcribed DNA N Kitsera, K Gasteiger, B Lühnsdorf, J Allgayer, B Epe, T Carell, A Khobta PLoS One 9 (4), e94405, 2014 | 23 | 2014 |
| Mouse CSB protein is important for gene expression in the presence of a single-strand break in the non-transcribed DNA strand A Khobta, T Lingg, I Schulz, D Warken, N Kitsera, B Epe DNA repair 9 (9), 985-993, 2010 | 23 | 2010 |
| Specific histone patterns and acetylase/deacetylase activity at the breakpoint-cluster region of the human MLL gene A Khobta, C Carlo-Stella, G Capranico Cancer research 64 (8), 2656-2662, 2004 | 19 | 2004 |
| Influences of histone deacetylase inhibitors and resveratrol on DNA repair and chromatin compaction B Keuser, A Khobta, K Gallé, S Anderhub, I Schulz, K Pauly, B Epe Mutagenesis 28 (5), 569-576, 2013 | 15 | 2013 |
| Generation and characterization of tTS‐H4: a novel transcriptional repressor that is compatible with the reverse tetracycline‐controlled TET‐ON system E Bockamp, C Christel, D Hameyer, A Khobta, M Maringer, M Reis, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2007 | 15 | 2007 |
