Acidosis significantly alters immune checkpoint expression profiles of T cells from oesophageal adenocarcinoma patients M Davern, NE Donlon, F O’Connell, C Gaughan, C O’Donovan, ... Cancer Immunology, Immunotherapy 72 (1), 55-71, 2023 | 18 | 2023 |
The impact of esophageal oncological surgery on perioperative immune function; implications for adjuvant immune checkpoint inhibition NE Donlon, M Davern, AD Sheppard, F O’Connell, MR Dunne, C Hayes, ... Frontiers in Immunology 13, 823225, 2022 | 10 | 2022 |
The omentum in obesity-associated cancer: A hindrance to effective natural killer cell migration towards tumour which can be overcome by CX3CR1 antagonism E Mylod, F O’Connell, NE Donlon, C Butler, JV Reynolds, J Lysaght, ... Cancers 14 (1), 64, 2021 | 8 | 2021 |
Impact of radiotherapy on the immune landscape in oesophageal adenocarcinoma NE Donlon, M Davern, F O’Connell, A Sheppard, A Heeran, A Bhardwaj, ... World Journal of Gastroenterology 28 (21), 2302, 2022 | 6 | 2022 |
Cooperation between chemotherapy and immune checkpoint blockade to enhance anti-tumour T cell immunity in oesophageal adenocarcinoma M Davern, NE Donlon, F O’Connell, AD Sheppard, C Hayes, R King, ... Translational Oncology 20, 101406, 2022 | 5 | 2022 |
Energy metabolism, metabolite, and inflammatory profiles in human ex vivo adipose tissue are influenced by obesity status, metabolic dysfunction, and treatment regimes in … F O’Connell, E Mylod, NE Donlon, AB Heeran, C Butler, A Bhardwaj, ... Cancers 15 (6), 1681, 2023 | 4 | 2023 |
Visceral adipose tissue secretome from early and late-stage oesophageal cancer patients differentially affects effector and regulatory T cells M Davern, D Bracken-Clarke, NE Donlon, AD Sheppard, FO Connell, ... Journal of Cancer Research and Clinical Oncology 149 (9), 6583-6599, 2023 | 3 | 2023 |
PD-1 blockade attenuates surgery-mediated immunosuppression and boosts Th1 immunity perioperatively in oesophagogastric junctional adenocarcinoma M Davern, C Gaughan, F O’Connell, B Moran, E Mylod, AD Sheppard, ... Frontiers in Immunology 14, 1150754, 2023 | 3 | 2023 |
Chrono-tailored drug delivery systems: recent advances and future directions CT Butler, AM Rodgers, AM Curtis, RF Donnelly Drug Delivery and Translational Research, 1-20, 2024 | 2 | 2024 |
Real-time ex vivo monitoring of NK cell migration toward obesity-associated oesophageal adenocarcinoma following modulation of CX3CR1 E Mylod, F O’Connell, NE Donlon, M Davern, C Marion, C Butler, ... Scientific Reports 14 (1), 4017, 2024 | 1 | 2024 |
Potential of damage associated molecular patterns in synergising radiation and the immune response in oesophageal cancer NE Donlon, M Davern, A Sheppard, F O'Connell, B Moran, TS Nugent, ... World Journal of Gastrointestinal Oncology 15 (8), 1349, 2023 | 1 | 2023 |
Analysing the Combined Effects of Radiotherapy and Chemokine Receptor 5 Antagonism: Complementary Approaches to Promote T Cell Function and Migration in Oesophageal Adenocarcinoma M Davern, C O’Donovan, NE Donlon, E Mylod, C Gaughan, A Bhardwaj, ... Biomedicines 12 (4), 819, 2024 | | 2024 |
Exploring the immune-metabolic mechanisms of adipose tissue in oesophageal adenocarcinoma F O'Connell, E Mylod, AB Heeran, NE Donlon, M Davern, C Butler, ... Cancer Research 82 (12_Supplement), 1990-1990, 2022 | | 2022 |
Immune Checkpoint Blockade Limits the Immunosuppressive Effects of The Oesophageal Adenocarcinoma Tumour Microenvironment On T-Cells M Davern, N Donlon, C Butler, N Ravi, JV Reynolds, J Lysaght, ... IRISH JOURNAL OF MEDICAL SCIENCE 190 (SUPPL 6), S264-S264, 2021 | | 2021 |
The Secretome of Visceral Adipose Tissue from Advanced Stage Oesophageal Adenocarcinoma Patients Dampened Anti-Tumour Immunity Ex Vivo; Implications for The Potential Use Of … DB Clarke, M Davern, E Mylod, C Butler, C Donohoe, A Bhardwaj, N Ravi, ... IRISH JOURNAL OF MEDICAL SCIENCE 190 (SUPPL 6), S244-S244, 2021 | | 2021 |
P09. 04 Impact of major oncologic surgery on immune responses in the immediate post-operative setting in oesophageal adenocarcinoma patients; a guide to harnessing the double … NE Donlon, M Davern, A Sheppard, F O’Connell, S Ramjit, C Hayes, ... Journal for ImmunoTherapy of Cancer 9 (Suppl 1), 2021 | | 2021 |
P09. 07 Novel insights into immune-independent functions of immune checkpoint inhibitors in oesophageal adenocarcinoma; potential implications for designing combination immuno … M Davern, C Buckley, C Fitzgerald, AB Heeran, NE Donlon, J McGrath, ... Journal for ImmunoTherapy of Cancer 9 (Suppl 1), 2021 | | 2021 |
The secretome of visceral adipose tissue from advanced stage oesophageal adenocarcinoma patients dampened anti-tumour immunity ex vivo; implications for the potential use of … M Davern, DB Clarke, NE Donlon, A Sheppard, FO Connell, K Majcher, ... EUROPEAN JOURNAL OF IMMUNOLOGY 51, 154-154, 2021 | | 2021 |
Immune checkpoint blockade limits the immunosuppressive effects exerted by key features of the hostile tumour microenvironment on T cells in oesophageal adenocarcinoma M Davern, NE Donlon, A Sheppard, FO Connell, R King, C Hayes, ... EUROPEAN JOURNAL OF IMMUNOLOGY 51, 189-189, 2021 | | 2021 |
Evaluation of methodologies to assess intracellular cGMP levels induced by soluble guanylate cyclase (sGC) stimulators in whole cells G Liu, C Butler, K Long, R Sarno, R Solinga, K Tang, Y Chien, K Carlson, ... Nitric Oxide, 131-132, 2014 | | 2014 |