Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein. RY Hampton, RG Gardner, J Rine Molecular biology of the cell 7 (12), 2029-2044, 1996 | 676 | 1996 |
Recognition and plasma clearance of endotoxin by scavenger receptors RY Hampton, DT Golenbock, M Penman, M Krieger, CRH Raetz Nature 352 (6333), 342-344, 1991 | 674 | 1991 |
ER-associated degradation in protein quality control and cellular regulation RY Hampton Current opinion in cell biology 14 (4), 476-482, 2002 | 593 | 2002 |
Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation NW Bays, RG Gardner, LP Seelig, CA Joazeiro, RY Hampton Nature cell biology 3 (1), 24-29, 2001 | 578 | 2001 |
Lipid A-like molecules that antagonize the effects of endotoxins on human monocytes. DT Golenbock, RY Hampton, N Qureshi, K Takayama, CR Raetz Journal of Biological Chemistry 266 (29), 19490-19498, 1991 | 537 | 1991 |
Endoplasmic reticulum degradation requires lumen to cytosol signaling: transmembrane control of Hrd1p by Hrd3p RG Gardner, GM Swarbrick, NW Bays, SR Cronin, S Wilhovsky, L Seelig, ... The Journal of cell biology 151 (1), 69-82, 2000 | 388 | 2000 |
HRD4/NPL4 Is Required for the Proteasomal Processing of Ubiquitinated ER Proteins NW Bays, SK Wilhovsky, A Goradia, K Hodgkiss-Harlow, RY Hampton Molecular biology of the cell 12 (12), 4114-4128, 2001 | 362 | 2001 |
Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1 JW Heck, SK Cheung, RY Hampton Proceedings of the National Academy of Sciences 107 (3), 1106-1111, 2010 | 313 | 2010 |
Regulated degradation of HMG-CoA reductase, an integral membrane protein of the endoplasmic reticulum, in yeast. RY Hampton, J Rine The Journal of cell biology 125 (2), 299-312, 1994 | 272 | 1994 |
Effects of overproduction of the catalytic domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase on squalene synthesis in Saccharomyces cerevisiae KA Donald, RY Hampton, IB Fritz Applied and environmental microbiology 63 (9), 3341-3344, 1997 | 262 | 1997 |
ER stress response: getting the UPR hand on misfolded proteins RY Hampton Current Biology 10 (14), R518-R521, 2000 | 244 | 2000 |
Misfolded membrane proteins are specifically recognized by the transmembrane domain of the Hrd1p ubiquitin ligase BK Sato, D Schulz, PH Do, RY Hampton Molecular cell 34 (2), 212-222, 2009 | 229 | 2009 |
Cod1p/Spf1p is a P-type ATPase involved in ER function and Ca2+ homeostasis SR Cronin, R Rao, RY Hampton The Journal of cell biology 157 (6), 1017-1028, 2002 | 209 | 2002 |
The biology of HMG-CoA reductase: the pros of contra-regulation R Hampton, D Dimster-Denk, J Rine Trends in biochemical sciences 21 (4), 140-145, 1996 | 203 | 1996 |
Cdc48–Ufd1–Npl4: stuck in the middle with Ub NW Bays, RY Hampton Current biology 12 (10), R366-R371, 2002 | 193 | 2002 |
A highly conserved signal controls degradation of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase in eukaryotes RG Gardner, RY Hampton Journal of Biological Chemistry 274 (44), 31671-31678, 1999 | 185 | 1999 |
Control of the innate immune response by the mevalonate pathway MK Akula, M Shi, Z Jiang, CE Foster, D Miao, AS Li, X Zhang, RM Gavin, ... Nature immunology 17 (8), 922-929, 2016 | 180 | 2016 |
Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase RY Hampton, H Bhakta Proceedings of the National Academy of Sciences 94 (24), 12944-12948, 1997 | 177 | 1997 |
Finding the will and the way of ERAD substrate retrotranslocation RY Hampton, T Sommer Current opinion in cell biology 24 (4), 460-466, 2012 | 171 | 2012 |
Unified nomenclature for subunits of the Saccharomyces cerevisie proteasome regulatory particle [2] D Finley, K Tanaka, C Mann, H Feldmann, M Hochstrasser, R Vierstra, ... Trends in biochemical sciences 23 (7), 244-245, 1998 | 162 | 1998 |