Progressive disruption of cellular protein folding in models of polyglutamine diseases T Gidalevitz, A Ben-Zvi, KH Ho, HR Brignull, RI Morimoto Science 311 (5766), 1471-1474, 2006 | 729 | 2006 |
The stress of protein misfolding: from single cells to multicellular organisms T Gidalevitz, V Prahlad, RI Morimoto Cold Spring Harbor perspectives in biology 3 (6), a009704, 2011 | 291 | 2011 |
Protein disulfide isomerase A6 controls the decay of IRE1α signaling via disulfide-dependent association D Eletto, D Eletto, D Dersh, T Gidalevitz, Y Argon Molecular cell 53 (4), 562-576, 2014 | 259 | 2014 |
Protein homeostasis in models of aging and age-related conformational disease EA Kikis, T Gidalevitz, RI Morimoto Protein Metabolism and Homeostasis in Aging, 138-159, 2010 | 221 | 2010 |
Destabilizing protein polymorphisms in the genetic background direct phenotypic expression of mutant SOD1 toxicity T Gidalevitz, T Krupinski, S Garcia, RI Morimoto PLoS genetics 5 (3), e1000399, 2009 | 219 | 2009 |
GRP94 is essential for mesoderm induction and muscle development because it regulates insulin-like growth factor secretion S Wanderling, BB Simen, O Ostrovsky, NT Ahmed, SM Vogen, ... Molecular biology of the cell 18 (10), 3764-3775, 2007 | 175 | 2007 |
Orchestration of secretory protein folding by ER chaperones T Gidalevitz, F Stevens, Y Argon Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (11), 2410-2424, 2013 | 164 | 2013 |
A cellular perspective on conformational disease: the role of genetic background and proteostasis networks T Gidalevitz, EA Kikis, RI Morimoto Current opinion in structural biology 20 (1), 23-32, 2010 | 122 | 2010 |
Hsp27 overexpression in the R6/2 mouse model of Huntington's disease: chronic neurodegeneration does not induce Hsp27 activation A Zourlidou, T Gidalevitz, M Kristiansen, C Landles, B Woodman, ... Human molecular genetics 16 (9), 1078-1090, 2007 | 114 | 2007 |
Identification of the N-terminal peptide binding site of glucose-regulated protein 94 T Gidalevitz, C Biswas, H Ding, D Schneidman-Duhovny, HJ Wolfson, ... Journal of Biological Chemistry 279 (16), 16543-16552, 2004 | 91 | 2004 |
Canine cystinuria: polymorphism in the canine SLC3A1 gene and identification of a nonsense mutation in cystinuric Newfoundland dogs. GU Henthorn PS, Liu J, Gidalevich T, Fang J, Casal ML, Patterson DF Human Genetics 107 (4), 295-303, 2000 | 91 | 2000 |
Radicicol-sensitive peptide binding to the N-terminal portion of GRP94 S Vogen, T Gidalevitz, C Biswas, BB Simen, E Stein, F Gulmen, Y Argon Journal of Biological Chemistry 277 (43), 40742-40750, 2002 | 90 | 2002 |
The peptide-binding activity of GRP94 is regulated by calcium C Biswas, O Ostrovsky, CA Makarewich, S Wanderling, T Gidalevitz, ... Biochemical Journal 405 (2), 233-241, 2007 | 79 | 2007 |
Multiple molecular mechanisms rescue mtDNA disease in C. elegans S Haroon, A Li, JL Weinert, C Fritsch, NG Ericson, J Alexander-Floyd, ... Cell reports 22 (12), 3115-3125, 2018 | 43 | 2018 |
Natural genetic variation determines susceptibility to aggregation or toxicity in a C. elegansmodel for polyglutamine disease T Gidalevitz, N Wang, T Deravaj, J Alexander-Floyd, RI Morimoto BMC biology 11, 1-12, 2013 | 42 | 2013 |
The special unfolded protein response in plasma cells D Ricci, T Gidalevitz, Y Argon Immunological reviews 303 (1), 35-51, 2021 | 17 | 2021 |
HSP-4/BiP expression in secretory cells is regulated by a developmental program and not by the unfolded protein response J Zha, M Ying, J Alexander-Floyd, T Gidalevitz PLoS biology 17 (3), e3000196, 2019 | 16 | 2019 |
A bystander mechanism explains the specific phenotype of a broadly expressed misfolded protein L Klabonski, J Zha, L Senthilkumar, T Gidalevitz PLoS genetics 12 (12), e1006450, 2016 | 16 | 2016 |
Candidate genes that affect aging through protein homeostasis Y Argon, T Gidalevitz Longevity Genes: A Blueprint for Aging, 45-72, 2015 | 16 | 2015 |
HspB1 overexpression improves life span and stress resistance in an invertebrate model CC Alexander, E Munkáscy, H Tillmon, T Fraker, J Scheirer, D Holstein, ... The Journals of Gerontology: Series A 77 (2), 268-275, 2022 | 11 | 2022 |