Heparan sulfate and heparin interactions with proteins MCZ Meneghetti, AJ Hughes, TR Rudd, HB Nader, AK Powell, EA Yates, ... Journal of the Royal Society Interface 12 (110), 20150589, 2015 | 290 | 2015 |
Structural photoactivation of a full-length bacterial phytochrome A Björling, O Berntsson, H Lehtivuori, H Takala, AJ Hughes, M Panman, ... Science advances 2 (8), e1600920, 2016 | 120 | 2016 |
Sequential conformational transitions and α-helical supercoiling regulate a sensor histidine kinase O Berntsson, RP Diensthuber, MR Panman, A Björling, E Gustavsson, ... Nature communications 8 (1), 284, 2017 | 72 | 2017 |
On the (un) coupling of the chromophore, tongue interactions, and overall conformation in a bacterial phytochrome H Takala, HK Lehtivuori, O Berntsson, A Hughes, R Nanekar, S Niebling, ... Journal of Biological Chemistry 293 (21), 8161-8172, 2018 | 57 | 2018 |
Chemically modified, non-anticoagulant heparin derivatives are potent galectin-3 binding inhibitors and inhibit circulating galectin-3-promoted metastasis CA Duckworth, SE Guimond, P Sindrewicz, AJ Hughes, NS French, ... Oncotarget 6 (27), 23671, 2015 | 54 | 2015 |
A non-hemorrhagic hybrid heparin/heparan sulfate with anticoagulant potential AS Brito, RS Cavalcante, LCGF Palhares, AJ Hughes, GPV Andrade, ... Carbohydrate polymers 99, 372-378, 2014 | 49 | 2014 |
Analysis of the fibroblast growth factor receptor (FGFR) signalling network with heparin as coreceptor: evidence for the expansion of the core FGFR signalling network R Xu, TR Rudd, AJ Hughes, G Siligardi, DG Fernig, EA Yates The FEBS journal 280 (10), 2260-2270, 2013 | 42 | 2013 |
Time-resolved X-ray solution scattering reveals the structural photoactivation of a light-oxygen-voltage photoreceptor O Berntsson, RP Diensthuber, MR Panman, A Björling, AJ Hughes, ... Structure 25 (6), 933-938. e3, 2017 | 40 | 2017 |
Photoactivation of Drosophila melanogaster cryptochrome through sequential conformational transitions O Berntsson, R Rodriguez, L Henry, MR Panman, AJ Hughes, C Einholz, ... Science advances 5 (7), eaaw1531, 2019 | 32 | 2019 |
Observing the structural evolution in the photodissociation of diiodomethane with femtosecond solution X-ray scattering MR Panman, E Biasin, O Berntsson, M Hermann, S Niebling, AJ Hughes, ... Physical Review Letters 125 (22), 226001, 2020 | 29 | 2020 |
Antithrombin stabilisation by sulfated carbohydrates correlates with anticoagulant activity MA Lima, AJ Hughes, N Veraldi, TR Rudd, R Hussain, AS Brito, ... MedChemComm 4 (5), 870-873, 2013 | 28 | 2013 |
Heparin derivatives for the targeting of multiple activities in the inflammatory response N Veraldi, AJ Hughes, TR Rudd, HB Thomas, SW Edwards, L Hadfield, ... Carbohydrate polymers 117, 400-407, 2015 | 26 | 2015 |
New light on the mechanism of phototransduction in phototropin L Henry, O Berntsson, MR Panman, A Cellini, AJ Hughes, I Kosheleva, ... Biochemistry 59 (35), 3206-3215, 2020 | 11 | 2020 |
Assessing the ability of spectroscopic methods to determine the difference in the folding propensities of highly similar β-hairpins H Andersson, E Danelius, P Jarvoll, S Niebling, AJ Hughes, S Westenhoff, ... ACS omega 2 (2), 508-516, 2017 | 11 | 2017 |
A zinc complex of heparan sulfate destabilises lysozyme and alters its conformation AJ Hughes, R Hussain, C Cosentino, M Guerrini, G Siligardi, EA Yates, ... Biochemical and biophysical research communications 425 (4), 794-799, 2012 | 11 | 2012 |
Investigating the relationship between temperature, conformation and calcium binding in heparin model oligosaccharides A Hughes, M Meneghetti, TY Huang, SC Hung, S Elli, M Guerrini, T Rudd, ... Carbohydrate research 438, 58-64, 2017 | 9 | 2017 |
Heparan sulphate, its derivatives and analogues share structural characteristics that can be exploited, particularly in inhibiting microbial attachment TR Rudd, A Hughes, J Holman, V Solari, E de Oliveira Ferreira, ... Brazilian Journal of Medical and Biological Research 45, 386-391, 2012 | 8 | 2012 |
E. a. Yates and M. a. Lima MCZ Meneghetti, AJ Hughes, TR Rudd, HB Nader, AK Powell JR Soc., Interface 12, 20150589, 2015 | 3 | 2015 |
Detection of interaction between protein trytophan residues and small or macromolecular ligands by synchrotron radiation magnetic circular dichroism AJ Hughes, TR Rudd, GSA Wright, DG Fernig, G Siligardi, EA Yates Analytical methods 7 (5), 1667-1671, 2015 | 2 | 2015 |
Light induced charge and energy transport in nucleic acids and proteins: general discussion A Chattopadhyay, R Cogdell, CE Crespo-Hernández, A Datta, A De, ... Faraday Discussions 207, 153-180, 2018 | 1 | 2018 |