关注
Marco Vignuzzi
Marco Vignuzzi
Agency for Science, Technology and Research A*STAR Singapore
在 idlabs.a-star.edu.sg 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ...
Nature 583 (7816), 459-468, 2020
44152020
Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population
M Vignuzzi, JK Stone, JJ Arnold, CE Cameron, R Andino
Nature 439 (7074), 344-348, 2006
12652006
The global phosphorylation landscape of SARS-CoV-2 infection
M Bouhaddou, D Memon, B Meyer, KM White, VV Rezelj, MC Marrero, ...
Cell 182 (3), 685-712. e19, 2020
8792020
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ...
Science 370 (6521), eabe9403, 2020
6262020
Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics
EC Smith, H Blanc, M Vignuzzi, MR Denison
PLoS pathogens 9 (8), e1003565, 2013
4772013
An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike
M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ...
Science 370 (6523), 1473-1479, 2020
3772020
Curcumin inhibits Zika and chikungunya virus infection by inhibiting cell binding
BC Mounce, T Cesaro, L Carrau, T Vallet, M Vignuzzi
Antiviral research 142, 148-157, 2017
3682017
Engineering attenuated virus vaccines by controlling replication fidelity
M Vignuzzi, E Wendt, R Andino
Nature medicine 14 (2), 154-161, 2008
3082008
Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A
KM White, R Rosales, S Yildiz, T Kehrer, L Miorin, E Moreno, S Jangra, ...
Science 371 (6532), 926-931, 2021
3052021
Evolutionary constraints on chaperone-mediated folding provide an antiviral approach refractory to development of drug resistance
R Geller, M Vignuzzi, R Andino, J Frydman
Genes & development 21 (2), 195-205, 2007
3022007
Arbovirus high fidelity variant loses fitness in mosquitoes and mice
LL Coffey, Y Beeharry, AV Bordería, H Blanc, M Vignuzzi
Proceedings of the National Academy of Sciences 108 (38), 16038-16043, 2011
2782011
Defective viral genomes are key drivers of the virus–host interaction
M Vignuzzi, CB López
Nature microbiology 4 (7), 1075-1087, 2019
2612019
Homology-based identification of a mutation in the coronavirus RNA-dependent RNA polymerase that confers resistance to multiple mutagens
NR Sexton, EC Smith, H Blanc, M Vignuzzi, OB Peersen, MR Denison
Journal of virology 90 (16), 7415-7428, 2016
2242016
Harnessing endogenous miRNAs to control virus tissue tropism as a strategy for developing attenuated virus vaccines
D Barnes, M Kunitomi, M Vignuzzi, K Saksela, R Andino
Cell host & microbe 4 (3), 239-248, 2008
2122008
Virus-derived DNA drives mosquito vector tolerance to arboviral infection
B Goic, KA Stapleford, L Frangeul, AJ Doucet, V Gausson, H Blanc, ...
Nature communications 7 (1), 12410, 2016
1992016
Ribavirin and lethal mutagenesis of poliovirus: molecular mechanisms, resistance and biological implications
M Vignuzzi, JK Stone, R Andino
Virus research 107 (2), 173-181, 2005
1992005
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2
N Drayman, JK DeMarco, KA Jones, SA Azizi, HM Froggatt, K Tan, ...
Science 373 (6557), 931-936, 2021
1932021
Remote Site Control of an Active Site Fidelity Checkpoint in a ViralRNA-dependent RNAPolymerase
JJ Arnold, M Vignuzzi, JK Stone, R Andino, CE Cameron
Journal of Biological Chemistry 280 (27), 25706-25716, 2005
1932005
Host alternation of chikungunya virus increases fitness while restricting population diversity and adaptability to novel selective pressures
LL Coffey, M Vignuzzi
Journal of virology 85 (2), 1025-1035, 2011
1912011
Large-scale phylogenomic analysis reveals the complex evolutionary history of rabies virus in multiple carnivore hosts
C Troupin, L Dacheux, M Tanguy, C Sabeta, H Blanc, C Bouchier, ...
PLoS pathogens 12 (12), e1006041, 2016
1802016
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