Combined CRISPRi/a-based chemical genetic screens reveal that rigosertib is a microtubule-destabilizing agent M Jost, Y Chen, LA Gilbert, MA Horlbeck, L Krenning, G Menchon, A Rai, ... Molecular cell 68 (1), 210-223. e6, 2017 | 228 | 2017 |
CLASP suppresses microtubule catastrophes through a single TOG domain A Aher, M Kok, A Sharma, A Rai, N Olieric, R Rodriguez-Garcia, ... Developmental cell 46 (1), 40-58. e8, 2018 | 101 | 2018 |
Imino–Phenolic–Pyridyl Conjugates of Calix[4]arene (L1 and L2) as Primary Fluorescence Switch-on Sensors for Zn2+ in Solution and in HeLa Cells and the Recognition of … R Kumar Pathak, V Kumar Hinge, A Rai, D Panda, C Pulla Rao Inorganic Chemistry 51 (9), 4994-5005, 2012 | 93 | 2012 |
Dinuclear copper (I) complexes containing cyclodiphosphazane derivatives and pyridyl ligands: synthesis, structural studies, and antiproliferative activity toward human … MS Balakrishna, D Suresh, A Rai, JT Mague, D Panda Inorganic chemistry 49 (19), 8790-8801, 2010 | 88 | 2010 |
Pyrophosphate Sensing by a Fluorescent Zn2+ Bound Triazole Linked Imino-Thiophenyl Conjugate of Calix[4]arene in HEPES Buffer Medium: Spectroscopy … RK Pathak, K Tabbasum, A Rai, D Panda, CP Rao Analytical chemistry 84 (11), 5117-5123, 2012 | 80 | 2012 |
Molecular modelling and competition binding study of Br-noscapine and colchicine provide insight into noscapinoid–tubulin binding site PK Naik, S Santoshi, A Rai, HC Joshi Journal of Molecular Graphics and Modelling 29 (7), 947-955, 2011 | 71 | 2011 |
Kinesin-4 KIF21B is a potent microtubule pausing factor WE Van Riel, A Rai, S Bianchi, EA Katrukha, Q Liu, AJR Heck, ... Elife 6, e24746, 2017 | 69 | 2017 |
CXI-benzo-84 reversibly binds to tubulin at colchicine site and induces apoptosis in cancer cells A Rai, TK Gupta, S Kini, A Kunwar, A Surolia, D Panda Biochemical pharmacology 86 (3), 378-391, 2013 | 51 | 2013 |
Cd2+ Complex of a Triazole-Based Calix[4]arene Conjugate as a Selective Fluorescent Chemosensor for Cys RK Pathak, VK Hinge, K Mahesh, A Rai, D Panda, CP Rao Analytical chemistry 84 (15), 6907-6913, 2012 | 51 | 2012 |
Short linear sequence motif LxxPTPh targets diverse proteins to growing microtubule ends A Kumar, C Manatschal, A Rai, I Grigoriev, MS Degen, R Jaussi, ... Structure 25 (6), 924-932. e4, 2017 | 49 | 2017 |
Taxanes convert regions of perturbed microtubule growth into rescue sites A Rai, T Liu, S Glauser, EA Katrukha, J Estévez-Gallego, ... Nature Materials 19 (3), 355-365, 2020 | 47 | 2020 |
Transcription factor NF-κB associates with microtubules and stimulates apoptosis in response to suppression of microtubule dynamics in MCF-7 cells A Rai, S Kapoor, S Singh, BP Chatterji, D Panda Biochemical pharmacology 93 (3), 277-289, 2015 | 44 | 2015 |
SB-RA-2001 inhibits bacterial proliferation by targeting FtsZ assembly D Singh, A Bhattacharya, A Rai, HPS Dhaked, D Awasthi, I Ojima, ... Biochemistry 53 (18), 2979-2992, 2014 | 44 | 2014 |
An antitubulin agent BCFMT inhibits proliferation of cancer cells and induces cell death by inhibiting microtubule dynamics A Rai, A Surolia, D Panda Public Library of Science 7 (8), e44311, 2012 | 43 | 2012 |
Structural determinants of microtubule minus end preference in CAMSAP CKK domains J Atherton, Y Luo, S Xiang, C Yang, A Rai, K Jiang, M Stangier, A Vemu, ... Nature communications 10 (1), 5236, 2019 | 39 | 2019 |
A drug discovery platform to identify compounds that inhibit EGFR triple mutants P Saraon, J Snider, Y Kalaidzidis, LE Wybenga-Groot, K Weiss, A Rai, ... Nature chemical biology 16 (5), 577-586, 2020 | 37 | 2020 |
A Zn 2+ specific triazole based calix [4] arene conjugate (L) as a fluorescence sensor for histidine and cysteine in HEPES buffer milieu RK Pathak, K Tabbasum, A Rai, D Panda, CP Rao Analyst 137 (17), 4069-4075, 2012 | 35 | 2012 |
Pharmaceutical-grade rigosertib is a microtubule-destabilizing agent M Jost, Y Chen, LA Gilbert, MA Horlbeck, L Krenning, G Menchon, A Rai, ... Molecular cell 79 (1), 191-198. e3, 2020 | 33 | 2020 |
Lattice defects induced by microtubule-stabilizing agents exert a long-range effect on microtubule growth by promoting catastrophes A Rai, T Liu, EA Katrukha, J Estévez-Gallego, SW Manka, I Paterson, ... Proceedings of the National Academy of Sciences 118 (51), e2112261118, 2021 | 25 | 2021 |
Enhanced stability of microtubules contributes in the development of colchicine resistance in MCF-7 cells A Rai, S Kapoor, A Naaz, MK Santra, D Panda Biochemical Pharmacology 132, 38-47, 2017 | 21 | 2017 |