| Kinetic mechanism of DNA polymerase I (Klenow) RD Kuchta, V Mizrahi, PA Benkovic, KA Johnson, SJ Benkovic Biochemistry 26 (25), 8410-8417, 1987 | 502 | 1987 |
| A new view into the regulation of purine metabolism: the purinosome AM Pedley, SJ Benkovic Trends in biochemical sciences 42 (2), 141-154, 2017 | 467 | 2017 |
| Replisome-mediated DNA replication SJ Benkovic, AM Valentine, F Salinas Annual review of biochemistry 70 (1), 181-208, 2001 | 428 | 2001 |
| Chemical basis for enzyme catalysis TC Bruice, SJ Benkovic Biochemistry 39 (21), 6267-6274, 2000 | 408 | 2000 |
| Interaction of dihydrofolate reductase with methotrexate: ensemble and single-molecule kinetics PTR Rajagopalan, Z Zhang, L McCourt, M Dwyer, SJ Benkovic, ... Proceedings of the National Academy of Sciences 99 (21), 13481-13486, 2002 | 399 | 2002 |
| DNA polymerase fidelity: kinetics, structure, and checkpoints CM Joyce, SJ Benkovic Biochemistry 43 (45), 14317-14324, 2004 | 398 | 2004 |
| Metallo-β-lactamase: structure and mechanism Z Wang, W Fast, AM Valentine, SJ Benkovic Current opinion in chemical biology 3 (5), 614-622, 1999 | 394 | 1999 |
| Surface sites for engineering allosteric control in proteins J Lee, M Natarajan, VC Nashine, M Socolich, T Vo, WP Russ, ... Science 322 (5900), 438-442, 2008 | 391 | 2008 |
| Controlling cell–cell interactions using surface acoustic waves F Guo, P Li, JB French, Z Mao, H Zhao, S Li, N Nama, JR Fick, ... Proceedings of the National Academy of Sciences 112 (1), 43-48, 2015 | 388 | 2015 |
| Kinetic mechanism whereby DNA polymerase I (Klenow) replicates DNA with high fidelity RD Kuchta, P Benkovic, SJ Benkovic Biochemistry 27 (18), 6716-6725, 1988 | 388 | 1988 |
| Cloning of the immunological repertoire in Escherichia coli for generation of monoclonal catalytic antibodies: construction of a heavy chain variable region-specific cDNA library. L Sastry, M Alting-Mees, WD Huse, JM Short, JA Sorge, BN Hay, ... Proceedings of the National Academy of Sciences 86 (15), 5728-5732, 1989 | 343 | 1989 |
| Induction of an antibody that catalyzes the hydrolysis of an amide bond KD Janda, D Schloeder, SJ Benkovic, RA Lerner Science 241 (4870), 1188-1191, 1988 | 339 | 1988 |
| Design and evolution of new catalytic activity with an existing protein scaffold HS Park, SH Nam, JK Lee, CN Yoon, B Mannervik, SJ Benkovic, HS Kim Science 311 (5760), 535-538, 2006 | 330 | 2006 |
| Backbone dynamics in dihydrofolate reductase complexes: role of loop flexibility in the catalytic mechanism MJ Osborne, J Schnell, SJ Benkovic, HJ Dyson, PE Wright Biochemistry 40 (33), 9846-9859, 2001 | 315 | 2001 |
| Kinetic mechanism of DNA polymerase I (Klenow fragment): identification of a second conformational change and evaluation of the internal equilibrium constant ME Dahlberg, SJ Benkovic Biochemistry 30 (20), 4835-4843, 1991 | 311 | 1991 |
| Free-energy landscape of enzyme catalysis SJ Benkovic, GG Hammes, S Hammes-Schiffer Biochemistry 47 (11), 3317-3321, 2008 | 305 | 2008 |
| Boron-containing inhibitors of synthetases SJ Baker, JW Tomsho, SJ Benkovic Chemical Society Reviews 40 (8), 4279-4285, 2011 | 299 | 2011 |
| Kinetic characterization of the polymerase and exonuclease activities of the gene 43 protein of bacteriophage T4 TL Capson, JA Peliska, BF Kaboord, MW Frey, C Lively, M Dahlberg, ... Biochemistry 31 (45), 10984-10994, 1992 | 294 | 1992 |
| Flexibility, diversity, and cooperativity: pillars of enzyme catalysis GG Hammes, SJ Benkovic, S Hammes-Schiffer Biochemistry 50 (48), 10422-10430, 2011 | 287 | 2011 |
| Creating multiple-crossover DNA libraries independent of sequence identity S Lutz, M Ostermeier, GL Moore, CD Maranas, SJ Benkovic Proceedings of the National Academy of Sciences 98 (20), 11248-11253, 2001 | 270 | 2001 |
