Most LQT2 mutations reduce Kv11. 1 (hERG) current by a class 2 (trafficking-deficient) mechanism CL Anderson, BP Delisle, BD Anson, JA Kilby, ML Will, DJ Tester, Q Gong, ... Circulation 113 (3), 365-373, 2006 | 500 | 2006 |
Biology of cardiac arrhythmias: ion channel protein trafficking BP Delisle, BD Anson, S Rajamani, CT January Circulation research 94 (11), 1418-1428, 2004 | 270 | 2004 |
Drug‐induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine S Rajamani, LL Eckhardt, CR Valdivia, CA Klemens, BM Gillman, ... British journal of pharmacology 149 (5), 481-489, 2006 | 237 | 2006 |
Prediction of mortality from 12-lead electrocardiogram voltage data using a deep neural network S Raghunath, AE Ulloa Cerna, L Jing, DP VanMaanen, J Stough, ... Nature medicine 26 (6), 886-891, 2020 | 230 | 2020 |
Long QT syndrome–associated mutations in intrauterine fetal death L Crotti, DJ Tester, WM White, DC Bartos, R Insolia, A Besana, JD Kunic, ... Jama 309 (14), 1473-1482, 2013 | 199 | 2013 |
Large-scale mutational analysis of Kv11. 1 reveals molecular insights into type 2 long QT syndrome CL Anderson, CE Kuzmicki, RR Childs, CJ Hintz, BP Delisle, CT January Nature communications 5 (1), 5535, 2014 | 175 | 2014 |
Molecular heterogeneity of calcium channel β-subunits in canine and human heart: evidence for differential subcellular localization JD Foell, RC Balijepalli, BP Delisle, AMR Yunker, SL Robia, JW Walker, ... Physiological genomics 17 (2), 183-200, 2004 | 161 | 2004 |
Molecular and functional characterization of common polymorphisms in HERG (KCNH2) potassium channels BD Anson, MJ Ackerman, DJ Tester, ML Will, BP Delisle, CL Anderson, ... American Journal of Physiology-Heart and Circulatory Physiology 286 (6 …, 2004 | 149 | 2004 |
The cardiomyocyte molecular clock, regulation of Scn5a, and arrhythmia susceptibility EA Schroder, M Lefta, X Zhang, DC Bartos, HZ Feng, Y Zhao, ... American Journal of Physiology-Cell Physiology 304 (10), C954-C965, 2013 | 138 | 2013 |
Identification of the T-Type Calcium Channel (CaV3.1d) in Developing Mouse Heart LL Cribbs, BL Martin, EA Schroder, BB Keller, BP Delisle, J Satin Circulation research 88 (4), 403-407, 2001 | 138 | 2001 |
Thapsigargin selectively rescues the trafficking defective LQT2 channels G601S and F805C BP Delisle, CL Anderson, RC Balijepalli, BD Anson, TJ Kamp, CT January Journal of Biological Chemistry 278 (37), 35749-35754, 2003 | 116 | 2003 |
Fever-induced QTc prolongation and ventricular arrhythmias in individuals with type 2 congenital long QT syndrome AS Amin, LJ Herfst, BP Delisle, CA Klemens, MB Rook, CR Bezzina, ... The Journal of clinical investigation 118 (7), 2552-2561, 2008 | 115 | 2008 |
Potassium channels in the heart: structure, function and regulation E Grandi, MC Sanguinetti, DC Bartos, DM Bers, Y Chen‐Izu, ... The Journal of physiology 595 (7), 2209-2228, 2017 | 110 | 2017 |
Coexistence of hERG current block and disruption of protein trafficking in ketoconazole‐induced long QT syndrome H Takemasa, T Nagatomo, H Abe, K Kawakami, T Igarashi, T Tsurugi, ... British journal of pharmacology 153 (3), 439-447, 2008 | 108 | 2008 |
Molecular pathogenesis of long QT syndrome type 2 JL Smith, CL Anderson, DE Burgess, CS Elayi, CT January, BP Delisle Journal of Arrhythmia 32 (5), 373-380, 2016 | 100 | 2016 |
The promise and peril of precision medicine: phenotyping still matters most JP Ackerman, DC Bartos, JD Kapplinger, DJ Tester, BP Delisle, ... Mayo Clinic Proceedings 91 (11), 1606-1616, 2016 | 91 | 2016 |
The cardiomyocyte molecular clock regulates the circadian expression of Kcnh2 and contributes to ventricular repolarization EA Schroder, DE Burgess, X Zhang, M Lefta, JL Smith, A Patwardhan, ... Heart rhythm 12 (6), 1306-1314, 2015 | 85 | 2015 |
R231C mutation in KCNQ1 causes long QT syndrome type 1 and familial atrial fibrillation DC Bartos, S Duchatelet, DE Burgess, D Klug, I Denjoy, R Peat, ... Heart Rhythm 8 (1), 48-55, 2011 | 85 | 2011 |
Mechanism of inactivation gating of human T-type (low-voltage activated) calcium channels DE Burgess, O Crawford, BP Delisle, J Satin Biophysical Journal 82 (4), 1894-1906, 2002 | 72 | 2002 |
Kv11.1 (ERG1) K+ Channels Localize in Cholesterol and Sphingolipid Enriched Membranes and Are Modulated by Membrane Cholesterol R Balijepalli, B Delisle, SY Balijepalli, JD Foell, JK Slind, TJ Kamp, ... Channels 1 (4), 263-272, 2007 | 70 | 2007 |