| Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance S Ponnusamy, M Meyers-Needham, CE Senkal, SA Saddoughi, ... Future oncology 6 (10), 1603-1624, 2010 | 369 | 2010 |
| Roles of bioactive sphingolipids in cancer biology and therapeutics SA Saddoughi, P Song, B Ogretmen Lipids in health and disease, 413-440, 2008 | 309 | 2008 |
| Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A‐RIPK1‐dependent necroptosis SA Saddoughi, S Gencer, YK Peterson, KE Ward, A Mukhopadhyay, ... EMBO molecular medicine 5 (1), 105-121, 2013 | 300 | 2013 |
| PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells P Neviani, JG Harb, JJ Oaks, R Santhanam, CJ Walker, JJ Ellis, ... The Journal of clinical investigation 123 (10), 4144-4157, 2013 | 261 | 2013 |
| Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling A Mukhopadhyay, SA Saddoughi, P Song, I Sultan, S Ponnusamy, ... The FASEB Journal 23 (3), 751, 2009 | 256 | 2009 |
| Diverse functions of ceramide in cancer cell death and proliferation SA Saddoughi, B Ogretmen Advances in cancer research 117, 37-58, 2013 | 212 | 2013 |
| Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate Bcr-Abl1 stability and drug resistance by modulation of protein phosphatase 2A A Salas, S Ponnusamy, CE Senkal, M Meyers-Needham, SP Selvam, ... Blood, The Journal of the American Society of Hematology 117 (22), 5941-5952, 2011 | 150 | 2011 |
| Alteration of ceramide synthase 6/C16-ceramide induces activating transcription factor 6-mediated endoplasmic reticulum (ER) stress and apoptosis via perturbation of cellular … CE Senkal, S Ponnusamy, Y Manevich, M Meyers-Needham, ... Journal of Biological Chemistry 286 (49), 42446-42458, 2011 | 134 | 2011 |
| Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies JJ Oaks, R Santhanam, CJ Walker, S Roof, JG Harb, G Ferenchak, ... Blood, The Journal of the American Society of Hematology 122 (11), 1923-1934, 2013 | 132 | 2013 |
| Results of a Phase II Trial of Gemcitabine Plus Doxorubicin in Patients with Recurrent Head and Neck Cancers: Serum C18-Ceramide as a Novel Biomarker for … SA Saddoughi, E Garrett-Mayer, U Chaudhary, PE O'Brien, LB Afrin, ... Clinical Cancer Research 17 (18), 6097-6105, 2011 | 80 | 2011 |
| National trends in the epidemiology of malignant pleural mesothelioma: a national cancer data base study SA Saddoughi, ZM Abdelsattar, SH Blackmon The Annals of Thoracic Surgery 105 (2), 432-437, 2018 | 65 | 2018 |
| Comparison of laparoscopic versus open surgical management of Morgagni hernia MC Young, SA Saddoughi, JM Aho, WS Harmsen, MS Allen, ... The Annals of Thoracic Surgery 107 (1), 257-261, 2019 | 55 | 2019 |
| Off-target function of the sonic hedgehog inhibitor cyclopamine in mediating apoptosis via nitric oxide–dependent neutral sphingomyelinase 2/ceramide induction M Meyers-Needham, JA Lewis, S Gencer, RD Sentelle, SA Saddoughi, ... Molecular cancer therapeutics 11 (5), 1092-1102, 2012 | 51 | 2012 |
| Survival after surgical resection of stage IV esophageal cancer SA Saddoughi, JM Reinersman, YO Zhukov, J Taswell, K Mara, ... The annals of thoracic surgery 103 (1), 261-266, 2017 | 45 | 2017 |
| Surgical resection of rare esophageal cancers SA Saddoughi, J Taswell, WS Harmsen, ML Inra, SH Blackmon, ... The Annals of Thoracic Surgery 101 (1), 311-315, 2016 | 15 | 2016 |
| Analysis of esophagectomy margin practice and survival implications SA Saddoughi, KG Mitchell, MB Antonoff, KM Fruth, J Taswell, ... The Annals of Thoracic Surgery 113 (1), 209-216, 2022 | 8 | 2022 |
| FTY720 restores PP2A tumor suppressor activity in polycythemia vera CD34+ progenitors through inhibition of Jak2 V617F-and PI-3Kγ-dependent SET serine phosphorylation and … JJ Oaks, A Mukhopadhyay, R Santhanam, SA Saddoughi, P Neviani, ... Blood 118 (21), 2494, 2011 | 6 | 2011 |
| Pharmacologic restoration of PP2A activity and interference with the SET-PP2A interplay by FTY720 and its non-immunosuppressive derivative as a novel and efficient therapy for … JJ Oaks, A Mukhopadhyay, R Santhanam, SA Saddoughi, C Walker, ... Blood 116 (21), 775, 2010 | 5 | 2010 |
| Determinants of long-term survival decades after esophagectomy for esophageal cancer MK Abou Chaar, A Godin, WS Harmsen, C Wzientek, SA Saddoughi, ... The Annals of Thoracic Surgery 116 (5), 1036-1044, 2023 | 4 | 2023 |
| Lung transplantation long-term survival is worse in patients who have undergone previous cardiac surgery EM Schumer, SA Saddoughi, PJ Spencer, A Pochettino, RC Daly, ... European Journal of Cardio-Thoracic Surgery 62 (4), ezac437, 2022 | 4 | 2022 |
