| Hydrophobic fluorescent probes introduce artifacts into single molecule tracking experiments due to non-specific binding LC Zanetti-Domingues, CJ Tynan, DJ Rolfe, DT Clarke, ... PloS one 8 (9), e74200, 2013 | 199 | 2013 |
| A ‘pocket guide’to total internal reflection fluorescence ML Martin‐Fernandez, CJ Tynan, SED Webb Journal of microscopy 252 (1), 16-22, 2013 | 178 | 2013 |
| EGFR oligomerization organizes kinase-active dimers into competent signalling platforms SR Needham, SK Roberts, A Arkhipov, VP Mysore, CJ Tynan, ... Nature communications 7 (1), 13307, 2016 | 174 | 2016 |
| Focal adhesions are sites of integrin extension JA Askari, CJ Tynan, SED Webb, ML Martin-Fernandez, C Ballestrem, ... Journal of cell biology 188 (6), 891-903, 2010 | 140 | 2010 |
| Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor J Ho, X Yang, SA Nikou, N Kichik, A Donkin, NO Ponde, JP Richardson, ... Nature Communications 10 (1), 2297, 2019 | 132 | 2019 |
| Single-molecule imaging and fluorescence lifetime imaging microscopy show different structures for high-and low-affinity epidermal growth factor receptors in A431 cells SED Webb, SK Roberts, SR Needham, CJ Tynan, DJ Rolfe, MD Winn, ... Biophysical journal 94 (3), 803-819, 2008 | 110 | 2008 |
| The architecture of EGFR’s basal complexes reveals autoinhibition mechanisms in dimers and oligomers LC Zanetti-Domingues, D Korovesis, SR Needham, CJ Tynan, S Sagawa, ... Nature communications 9 (1), 4325, 2018 | 76 | 2018 |
| Automated multidimensional single molecule fluorescence microscopy feature detection and tracking DJ Rolfe, CI McLachlan, M Hirsch, SR Needham, CJ Tynan, SED Webb, ... European biophysics journal 40, 1167-1186, 2011 | 61 | 2011 |
| Human epidermal growth factor receptor (EGFR) aligned on the plasma membrane adopts key features of Drosophila EGFR asymmetry CJ Tynan, SK Roberts, DJ Rolfe, DT Clarke, HH Loeffler, J Kästner, ... Molecular and cellular biology 31 (11), 2241-2252, 2011 | 54 | 2011 |
| Self-association of calcium-binding protein S100A4 and metastasis TM Ismail, S Zhang, DG Fernig, S Gross, ML Martin-Fernandez, V See, ... Journal of biological chemistry 285 (2), 914-922, 2010 | 54 | 2010 |
| 3D visualization of additive occlusion and tunable full-spectrum fluorescence in calcite DC Green, J Ihli, PD Thornton, MA Holden, B Marzec, YY Kim, AN Kulak, ... Nature communications 7 (1), 13524, 2016 | 48 | 2016 |
| Multicolour single molecule imaging in cells with near infra-red dyes CJ Tynan, DT Clarke, BC Coles, DJ Rolfe, ML Martin-Fernandez, ... PloS one 7 (4), e36265, 2012 | 41 | 2012 |
| Structure–function relationships and supramolecular organization of the EGFR (epidermal growth factor receptor) on the cell surface SR Needham, LC Zanetti-Domingues, M Hirsch, DJ Rolfe, CJ Tynan, ... Biochemical Society Transactions 42 (1), 114-119, 2014 | 26 | 2014 |
| A tale of the epidermal growth factor receptor: The quest for structural resolution on cells CJ Tynan, VL Schiavo, L Zanetti-Domingues, SR Needham, SK Roberts, ... Methods 95, 86-93, 2016 | 20 | 2016 |
| Optics clustered to output unique solutions: A multi-laser facility for combined single molecule and ensemble microscopy DT Clarke, SW Botchway, BC Coles, SR Needham, SK Roberts, DJ Rolfe, ... Review of Scientific Instruments 82 (9), 2011 | 20 | 2011 |
| Supramolecular clustering of the cardiac sodium channel Nav1. 5 in HEK293F cells, with and without the auxiliary β3‐subunit SC Salvage, JS Rees, A McStea, M Hirsch, L Wang, CJ Tynan, MW Reed, ... The FASEB Journal 34 (3), 3537, 2020 | 15 | 2020 |
| Nanometric molecular separation measurements by single molecule photobleaching SED Webb, M Hirsch, SR Needham, BC Coles, KM Scherer, SK Roberts, ... Methods 88, 76-80, 2015 | 15 | 2015 |
| The Rho family GEF FARP2 is activated by aPKCι to control tight junction formation and polarity A Elbediwy, Y Zhang, M Cobbaut, P Riou, RS Tan, SK Roberts, C Tynan, ... Journal of Cell Science 132 (8), jcs223743, 2019 | 13 | 2019 |
| Determining the geometry of oligomers of the human epidermal growth factor family on cells with 7 nm resolution LC Zanetti-Domingues, M Hirsch, CJ Tynan, DJ Rolfe, TV Boyadzhiev, ... Progress in biophysics and molecular biology 118 (3), 139-152, 2015 | 12 | 2015 |
| Investigating extracellular in situ EGFR structure and conformational changes using FRET microscopy SK Roberts, CJ Tynan, M Winn, ML Martin-Fernandez Biochemical Society Transactions 40 (1), 189-194, 2012 | 12 | 2012 |
