The species translation challenge—a systems biology perspective on human and rat bronchial epithelial cells C Poussin, C Mathis, LG Alexopoulos, DE Messinis, RHJ Dulize, ... Scientific Data 1 (1), 1-14, 2014 | 51 | 2014 |
MAPK pathway and B cells overactivation in multiple sclerosis revealed by phosphoproteomics and genomic analysis E Kotelnikova, NA Kiani, D Messinis, I Pertsovskaya, V Pliaka, ... Proceedings of the National Academy of Sciences 116 (19), 9671-9676, 2019 | 43 | 2019 |
Modeling of signaling pathways in chondrocytes based on phosphoproteomic and cytokine release data IN Melas, AD Chairakaki, EI Chatzopoulou, DE Messinis, T Katopodi, ... Osteoarthritis and Cartilage 22 (3), 509-518, 2014 | 40 | 2014 |
Combined logical and data-driven models for linking signalling pathways to cellular response IN Melas, A Mitsos, DE Messinis, TS Weiss, LG Alexopoulos BMC systems biology 5, 1-12, 2011 | 34 | 2011 |
Signaling networks in MS: a systems-based approach to developing new pharmacological therapies E Kotelnikova, M Bernardo-Faura, G Silberberg, NA Kiani, D Messinis, ... Multiple Sclerosis Journal 21 (2), 138-146, 2015 | 30 | 2015 |
Construction of large signaling pathways using an adaptive perturbation approach with phosphoproteomic data IN Melas, A Mitsos, DE Messinis, TS Weiss, JS Rodriguez, ... Molecular Biosystems 8 (5), 1571-1584, 2012 | 16 | 2012 |
Translational systems pharmacology‐based predictive assessment of drug‐induced cardiomyopathy DE Messinis, IN Melas, J Hur, N Varshney, LG Alexopoulos, JPF Bai CPT: Pharmacometrics & Systems Pharmacology 7 (3), 166-174, 2018 | 14 | 2018 |
A crowd-sourcing approach for the construction of species-specific cell signaling networks E Bilal, T Sakellaropoulos, C Participants, IN Melas, DE Messinis, ... Bioinformatics 31 (4), 484-491, 2014 | 12 | 2014 |
Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis M Bernardo-Faura, M Rinas, J Wirbel, I Pertsovskaya, V Pliaka, ... Genome Medicine 13, 1-16, 2021 | 11 | 2021 |
Network‐based analysis of nutraceuticals in human hepatocellular carcinomas reveals mechanisms of chemopreventive action M Michailidou, IN Melas, DE Messinis, S Klamt, LG Alexopoulos, ... CPT: pharmacometrics & systems pharmacology 4 (6), 350-361, 2015 | 7 | 2015 |
Systems pharmacology investigation of mechanism of action of nutraceuticals DE Messinis, DARS Latino, P Pospisil, C Poussin, MC Peitsch, J Hoeng Nutraceuticals, 345-361, 2021 | 4 | 2021 |
Systems biology reveals anatabine to be an NRF2 activator DE Messinis, C Poussin, DARS Latino, Y Eb-Levadoux, R Dulize, D Peric, ... Frontiers in Pharmacology 13, 1011184, 2022 | 3 | 2022 |
A computational platform and guide for acceleration of novel medicines and personalized medicine IN Melas, T Sakellaropoulos, J Hur, D Messinis, EY Guo, LG Alexopoulos, ... Bioinformatics and Drug Discovery, 181-198, 2019 | 1 | 2019 |
Συστημική μοντελοποίηση και ανάλυση μεγάλων δεδομένων για την αποκρυπτογράφηση μηχανισμών σε ανθρώπινες ασθένειες Δ Μεσσήνης | | 2018 |
saezlab/combiMS: combiMS code for Prediction of combination therapy based on perturbation modeling of the multiple sclerosis signaling network. Code started by Marti at EBI on … E Kotelnikova, NA Kiani, D Messinis, I Pertsovskaya, V Pliaka, ... Github, 2016 | | 2016 |
The role of inflammatory mediators in meniscus and cartilage crosstalk in osteoarthritis ZH Dailiana, EI Chatzopoulou, S Samara, IM Melas, M Hantes, ... Osteoarthritis and Cartilage 23, A267-A268, 2015 | | 2015 |
Comparison of the Biological Impact of Cigarette Smoke and a Prototypic Modified Risk Tobacco Product on Human versus Rat Primary Normal Bronchial Epithelial Cells U Kogel, C Poussin, DE Messinis, S Frentzel, C Mathis, J Hoeng, ... INTERNATIONAL JOURNAL OF TOXICOLOGY 34 (1), 86-87, 2015 | | 2015 |
Meniscus-Cartilage paracrine crosstalk in osteoarthritis S Samara, E Chatzopoulou, I Melas, D Messinis, Z Dailiana, P Kollia, ... Bone Abstracts 3, 2014 | | 2014 |
Transcription profiling by array of normal human and rat bronchial epithelial cells treated with more than 50 different compounds to investigate the ability to translate … V Belcastro, P Meyer, LG Alexopoulos, DE Messinis, JJ Rice, ... ArrayExpress, 2014 | | 2014 |
Reduced impact of a prototypic modified risk tobacco product compared with conventional cigarette smoke on exposed human and rat primary normal bronchial epithelial cells C Mathis, DE Messinis, U Kogel, C Poussin, S Frentzel, E Guedj, C Merg, ... Toxicology Letters, S73, 2014 | | 2014 |