| A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy M Yang, C Liang, K Swaminathan, S Herrlinger, F Lai, R Shiekhattar, ... Science advances 2 (9), e1601167, 2016 | 249 | 2016 |
| A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication Y Zhao, TS Soh, J Zheng, KWK Chan, WW Phoo, CC Lee, MYF Tay, ... PLoS pathogens 11 (3), e1004682, 2015 | 219 | 2015 |
| First-line antiretroviral therapy with a protease inhibitor versus non-nucleoside reverse transcriptase inhibitor and switch at higher versus low viral load in HIV-infected … PENPACT-1 (PENTA 9/PACTG 390) Study Team The Lancet infectious diseases 11 (4), 273-283, 2011 | 128 | 2011 |
| Structural analysis uncovers a role for redox in regulating FKBP13, an immunophilin of the chloroplast thylakoid lumen G Gopalan, Z He, Y Balmer, P Romano, R Gupta, A Héroux, BB Buchanan, ... Proceedings of the National Academy of Sciences 101 (38), 13945-13950, 2004 | 126 | 2004 |
| Crystal structure of a PUT3–DNA complex reveals a novel mechanism for DMA recognition by a protein containing a Zn2Cys6 binuclear cluster K Swaminathan, P Flynn, RJ Reece, R Marmorstein Nature structural biology 4 (9), 751-759, 1997 | 126 | 1997 |
| Crystal structure of the CDK4/6 inhibitory protein p18INK4c provides insights into ankyrin-like repeat structure/function and tumor-derived p16INK4 mutations R Venkataramani, K Swaminathan, R Marmorstein Nature structural biology 5 (1), 74-81, 1998 | 114 | 1998 |
| Enzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis K Hotta, X Chen, RS Paton, A Minami, H Li, K Swaminathan, II Mathews, ... Nature 483 (7389), 355-358, 2012 | 111 | 2012 |
| A dimerized coiled-coil domain and an adjoining part of geminin interact with two sites on Cdt1 for replication inhibition S Saxena, P Yuan, SK Dhar, T Senga, D Takeda, H Robinson, ... Molecular cell 15 (2), 245-258, 2004 | 106 | 2004 |
| Crystal structure of the polyextremophilic α-amylase AmyB from Halothermothrix orenii: details of a productive enzyme–substrate complex and an N domain with a role in binding … TC Tan, BN Mijts, K Swaminathan, BKC Patel, C Divne Journal of molecular biology 378 (4), 852-870, 2008 | 105 | 2008 |
| Structural basis for hormone recognition by the Human CRFR2α G protein-coupled receptor K Pal, K Swaminathan, HE Xu, AA Pioszak Journal of biological chemistry 285 (51), 40351-40361, 2010 | 97 | 2010 |
| A HEX-1 crystal lattice required for Woronin body function in Neurospora crassa P Yuan, G Jedd, D Kumaran, S Swaminathan, H Shio, D Hewitt, NH Chua, ... Nature Structural & Molecular Biology 10 (4), 264-270, 2003 | 97 | 2003 |
| Molecular basis for specific viral RNA recognition and 2′-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5) Y Zhao, TS Soh, SP Lim, KY Chung, K Swaminathan, SG Vasudevan, ... Proceedings of the National Academy of Sciences 112 (48), 14834-14839, 2015 | 95 | 2015 |
| Crystal structure of the PAC1R extracellular domain unifies a consensus fold for hormone recognition by class B G-protein coupled receptors S Kumar, A Pioszak, C Zhang, K Swaminathan, HE Xu PloS one 6 (5), e19682, 2011 | 92 | 2011 |
| Crystal structure of full-length Mycobacterium tuberculosis H37Rv glycogen branching enzyme: Insights of N-terminal β-sandwich in substrate specificity and enzymatic activity K Pal, S Kumar, S Sharma, SK Garg, MS Alam, HE Xu, P Agrawal, ... Journal of biological chemistry 285 (27), 20897-20903, 2010 | 92 | 2010 |
| Isomaltulose synthase (PalI) of Klebsiella sp. LX3: Crystal structure and implication of mechanism D Zhang, N Li, SM Lok, LH Zhang, K Swaminathan Journal of Biological Chemistry 278 (37), 35428-35434, 2003 | 92 | 2003 |
| Crystal structure of AmyA lacks acidic surface and provide insights into protein stability at poly-extreme condition N Sivakumar, N Li, JW Tang, BKC Patel, K Swaminathan FEBS letters 580 (11), 2646-2652, 2006 | 82 | 2006 |
| Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: conformational selection highlights a new concept in allosteric inhibitor design S Badireddy, G Yunfeng, M Ritchie, P Akamine, J Wu, CW Kim, SS Taylor, ... Molecular & Cellular Proteomics 10 (3), 2011 | 76 | 2011 |
| Structural and functional studies of trans-encoded HLA-DQ2. 3 (DQA1* 03: 01/DQB1* 02: 01) protein molecule S Tollefsen, K Hotta, X Chen, B Simonsen, K Swaminathan, II Mathews, ... Journal of Biological Chemistry 287 (17), 13611-13619, 2012 | 72 | 2012 |
| Engineering of serine protease for improved thermostability and catalytic activity using rational design NM Ashraf, A Krishnagopal, A Hussain, D Kastner, AMM Sayed, YK Mok, ... International journal of biological macromolecules 126, 229-237, 2019 | 65 | 2019 |
| Crystal Structure of Arabidopsis Cyclophilin38 Reveals a Previously Uncharacterized Immunophilin Fold and a Possible Autoinhibitory Mechanism D Vasudevan, A Fu, S Luan, K Swaminathan The Plant Cell 24 (6), 2666-2674, 2012 | 53 | 2012 |
