Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation EAA Nollen, SM Garcia, G Van Haaften, S Kim, A Chavez, RI Morimoto, ... Proceedings of the National Academy of Sciences 101 (17), 6403-6408, 2004 | 516 | 2004 |
Destabilizing protein polymorphisms in the genetic background direct phenotypic expression of mutant SOD1 toxicity T Gidalevitz, T Krupinski, S Garcia, RI Morimoto PLoS genetics 5 (3), e1000399, 2009 | 220 | 2009 |
Identification of small RNA pathway genes using patterns of phylogenetic conservation and divergence Y Tabach, AC Billi, GD Hayes, MA Newman, O Zuk, H Gabel, R Kamath, ... Nature 493 (7434), 694-698, 2013 | 152 | 2013 |
Neuronal signaling modulates protein homeostasis in Caenorhabditis elegans post-synaptic muscle cells SM Garcia, MO Casanueva, MC Silva, MD Amaral, RI Morimoto Genes & development 21 (22), 3006-3016, 2007 | 131 | 2007 |
Modeling polyglutamine pathogenesis in C. elegans HR Brignull, JF Morley, SM Garcia, RI Morimoto Methods in enzymology 412, 256-282, 2006 | 116 | 2006 |
Cystic fibrosis patients with the 3272‐26A→ G mutation have mild disease, leaky alternative mRNA splicing, and CFTR protein at the cell membrane S Beck, D Penque, S Garcia, A Gomes, C Farinha, L Mata, S Gulbenkian, ... Human mutation 14 (2), 133-144, 1999 | 92 | 1999 |
The Caenorhabditis elegans RDE-10/RDE-11 complex regulates RNAi by promoting secondary siRNA amplification C Zhang, TA Montgomery, SEJ Fischer, SMDA Garcia, CG Riedel, ... Current biology 22 (10), 881-890, 2012 | 64 | 2012 |
The chromatin remodeling factor ISW-1 integrates organismal responses against nuclear and mitochondrial stress O Matilainen, MSB Sleiman, PM Quiros, SMDA Garcia, J Auwerx Nature communications 8 (1), 1818, 2017 | 40 | 2017 |
Identification of genes in toxicity pathways of trinucleotide-repeat RNA in C. elegans SMDA Garcia, Y Tabach, GF Lourenço, M Armakola, G Ruvkun Nature structural & molecular biology 21 (8), 712-720, 2014 | 29 | 2014 |
Expanded CUG repeats trigger disease phenotype and expression changes through the RNAi machinery in C. elegans L Qawasmi, M Braun, I Guberman, E Cohen, L Naddaf, A Mellul, ... Journal of molecular biology 431 (9), 1711-1728, 2019 | 17 | 2019 |
Loss of muscleblind splicing factor shortens Caenorhabditis elegans lifespan by reducing the activity of p38 MAPK/PMK-1 and transcription factors ATF-7 and Nrf … O Matilainen, ARS Ribeiro, J Verbeeren, M Cetinbas, H Sood, ... Genetics 219 (2), iyab114, 2021 | 10 | 2021 |
The Muscleblind-like protein MBL-1 regulates microRNA expression in Caenorhabditis elegans through an evolutionarily conserved autoregulatory mechanism J Verbeeren, J Teixeira, SMDA Garcia PLoS Genetics 19 (12), e1011109, 2023 | 2 | 2023 |
Asymmetric inheritance of RNA toxicity in C. elegans expressing CTG repeats M Braun, S Shoshani, J Teixeira, AM Shtern, M Miller, Z Granot, ... Iscience 25 (5), 2022 | 2 | 2022 |
Towards understanding post-COVID-19 condition: A systematic meta-analysis of transcriptomic alterations with sex-specific insights EC Rusu, P Monfort-Lanzas, L Bertran, A Barrientos-Riosalido, E Solé, ... Computers in Biology and Medicine 175, 108507, 2024 | 1 | 2024 |
RNA interference mediates RNA toxicity with parent-of-origin effects in C. elegans expressing CTG repeats M Braun, S Shoshani, J Teixeira, AM Shtern, M Miller, Z Granot, ... bioRxiv, 2021.05. 19.444826, 2021 | 1 | 2021 |
Stress and misfolded proteins: modulators of neurodegenerative diseases and longevity RI Morimoto, J Morley, H Brignull, S Garcia, K Richter, C Kaiser FEBS JOURNAL 272, 2005 | 1 | 2005 |
RNA nucleotide repeats induce mitochondrial dysfunction and the ribosome-associated quality control J Teixeira, AM Harju, A Othman, O Eriksson, A Brandão, BJ Battersby, ... bioRxiv, 2021.09. 24.461665, 2021 | | 2021 |
The effects of mitochondrial-and histone stress on the C. elegans transcriptome OJ Matilainen, M Bou Sleiman, P Moral Quiros, SMDA Garcia, J Auwerx EPFL Infoscience, 2017 | | 2017 |
The CFTR folding defect modeled in C. elegans by MDR/CFTR chimeras and assessment of heavy metal resistance SMDA Garcia Pediatric Pulmonology, 2007 | | 2007 |