| Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease RB DeMattos, KR Bales, DJ Cummins, JC Dodart, SM Paul, DM Holtzman Proceedings of the National Academy of Sciences 98 (15), 8850-8855, 2001 | 1756 | 2001 |
| Synaptic activity regulates interstitial fluid amyloid-β levels in vivo JR Cirrito, KA Yamada, MB Finn, RS Sloviter, KR Bales, PC May, ... Neuron 48 (6), 913-922, 2005 | 1427 | 2005 |
| Human apoE isoforms differentially regulate brain amyloid-β peptide clearance JM Castellano, J Kim, FR Stewart, H Jiang, RB DeMattos, BW Patterson, ... Science translational medicine 3 (89), 89ra57-89ra57, 2011 | 1401 | 2011 |
| Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model JC Dodart, KR Bales, KS Gannon, SJ Greene, RB DeMattos, C Mathis, ... Nature neuroscience 5 (5), 452-457, 2002 | 1238 | 2002 |
| Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease DM Holtzman, KR Bales, T Tenkova, AM Fagan, M Parsadanian, ... Proceedings of the National Academy of Sciences 97 (6), 2892-2897, 2000 | 1139 | 2000 |
| Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition KR Bales, T Verina, RC Dodel, Y Du, L Altstiel, M Bender, P Hyslop, ... Nature genetics 17 (3), 263-264, 1997 | 1087 | 1997 |
| Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease Y Du, Z Ma, S Lin, RC Dodel, F Gao, KR Bales, LC Triarhou, E Chernet, ... Proceedings of the National Academy of Sciences 98 (25), 14669-14674, 2001 | 961 | 2001 |
| Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein OM Andersen, J Reiche, V Schmidt, M Gotthardt, R Spoelgen, J Behlke, ... Proceedings of the National Academy of Sciences 102 (38), 13461-13466, 2005 | 796 | 2005 |
| P-glycoprotein deficiency at the blood-brain barrier increases amyloid-β deposition in an Alzheimer disease mouse model JR Cirrito, R Deane, AM Fagan, ML Spinner, M Parsadanian, MB Finn, ... The Journal of clinical investigation 115 (11), 3285-3290, 2005 | 766 | 2005 |
| Brain to plasma amyloid-β efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease RB DeMattos, KR Bales, DJ Cummins, SM Paul, DM Holtzman science 295 (5563), 2264-2267, 2002 | 750 | 2002 |
| Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-β peptides M Koistinaho, S Lin, XIN Wu, M Esterman, D Koger, J Hanson, R Higgs, ... Nature medicine 10 (7), 719-726, 2004 | 699 | 2004 |
| Apolipoprotein E is essential for amyloid deposition in the APPV717F transgenic mouse model of Alzheimer's disease KR Bales, T Verina, DJ Cummins, Y Du, RC Dodel, J Saura, CE Fishman, ... Proceedings of the National Academy of Sciences 96 (26), 15233-15238, 1999 | 638 | 1999 |
| In vivo assessment of brain interstitial fluid with microdialysis reveals plaque-associated changes in amyloid-β metabolism and half-life JR Cirrito, PC May, MA O'Dell, JW Taylor, M Parsadanian, JW Cramer, ... Journal of Neuroscience 23 (26), 8844-8853, 2003 | 578 | 2003 |
| ApoE and clusterin cooperatively suppress Aβ levels and deposition: evidence that ApoE regulates extracellular Aβ metabolism in vivo RB DeMattos, JR Cirrito, M Parsadanian, PC May, MA O'Dell, JW Taylor, ... Neuron 41 (2), 193-202, 2004 | 558 | 2004 |
| Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease SE Wahrle, H Jiang, M Parsadanian, J Kim, A Li, A Knoten, S Jain, ... The Journal of clinical investigation 118 (2), 671-682, 2008 | 447 | 2008 |
| Expression of human apolipoprotein E reduces amyloid-β deposition in a mouse model of Alzheimer's disease DM Holtzman, KR Bales, S Wu, P Bhat, M Parsadanian, AM Fagan, ... The Journal of clinical investigation 103 (6), R15-R21, 1999 | 428 | 1999 |
| Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of … MM Racke, LI Boone, DL Hepburn, M Parsadainian, MT Bryan, DK Ness, ... Journal of Neuroscience 25 (3), 629-636, 2005 | 422 | 2005 |
| Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model DM Holtzman, AM Fagan, B Mackey, T Tenkova, L Sartorius, SM Paul, ... Annals of Neurology: Official Journal of the American Neurological …, 2000 | 401 | 2000 |
| Deletion of Abca1 increases Aβ deposition in the PDAPP transgenic mouse model of Alzheimer disease SE Wahrle, H Jiang, M Parsadanian, RE Hartman, KR Bales, SM Paul, ... Journal of Biological Chemistry 280 (52), 43236-43242, 2005 | 388 | 2005 |
| Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease RB DeMattos, MA O'dell, M Parsadanian, JW Taylor, JAK Harmony, ... Proceedings of the National Academy of Sciences 99 (16), 10843-10848, 2002 | 374 | 2002 |
