Synthesis and preclinical evaluation of TPA-based zinc chelators as metallo-β-lactamase inhibitors C Schnaars, G Kildahl-Andersen, A Prandina, R Popal, S Radix, ... ACS Infectious Diseases 4 (9), 1407-1422, 2018 | 42 | 2018 |
Total synthesis and antileukemic evaluations of the phenazine 5, 10-dioxide natural products iodinin, myxin and their derivatives EÖ Viktorsson, BM Grøthe, R Aesoy, M Sabir, S Snellingen, A Prandina, ... Bioorganic & medicinal chemistry 25 (7), 2285-2293, 2017 | 33 | 2017 |
Synthesis of a novel legumain-cleavable colchicine prodrug with cell-specific toxicity RL Smith, OAH Åstrand, LM Nguyen, T Elvestrand, G Hagelin, R Solberg, ... Bioorganic & Medicinal Chemistry 22 (13), 3309-3315, 2014 | 31 | 2014 |
Antimicrobial activity and cytotoxicity of Ag (I) and Au (I) pillarplexes A Pöthig, S Ahmed, HC Winther-Larsen, S Guan, PJ Altmann, ... Frontiers in chemistry 6, 584, 2018 | 30 | 2018 |
ZN148-a modular synthetic metallo-ß-lactamase inhibitor reverses carbapenem-resistance in Gram-negative pathogens in vivo. Ø Samuelsen, OAH Åstrand, C Fröhlich, A Heikal, S Skagseth, ... Antimicrobial Agents and Chemotherapeutics 64, e02415-19, 2020 | 27* | 2020 |
Synthesis and initial in vitro biological evaluation of two new zinc-chelating compounds: comparison with TPEN and PAC-1 OAH Åstrand, G Aziz, SF Ali, RE Paulsen, TV Hansen, P Rongved Bioorganic & medicinal chemistry 21 (17), 5175-5181, 2013 | 21 | 2013 |
Synthesis and biological evaluation of new dipicolylamine zinc chelators as metallo-β-lactamase inhibitors A Prandina, S Radix, M Le Borgne, LP Jordheim, Z Bousfiha, C Fröhlich, ... Tetrahedron 75 (11), 1525-1540, 2019 | 16 | 2019 |
Synthesis and characterization of new selective Zn2+ fluorescent probes for functionalization: in vitro Cell imaging applications OAH Åstrand, LPE Austdal, RE Paulsen, TV Hansen, P Rongved Tetrahedron 69 (40), 8645-8654, 2013 | 14 | 2013 |
Synthesis and biological evaluation of zinc chelating compounds as metallo-β-lactamase inhibitors G Kildahl-Andersen, C Schnaars, A Prandina, S Radix, M Le Borgne, ... Medchemcomm 10 (4), 528-537, 2019 | 13 | 2019 |
Degradative behavior and toxicity of alkylated imidazoles S Evjen, OA Høgmoen Åstrand, M Gaarder, RE Paulsen, A Fiksdahl, ... Industrial & Engineering Chemistry Research 59 (2), 587-595, 2019 | 9 | 2019 |
Development of new LXR modulators that regulate LXR target genes and reduce lipogenesis in human cell models OAH Åstrand, I Gikling, I Sylte, AC Rustan, GH Thoresen, P Rongved, ... European Journal of Medicinal Chemistry 74, 258-263, 2014 | 9 | 2014 |
Regulation of liver X receptor target genes by 22-functionalized oxysterols. Synthesis, in silico and in vitro evaluations EÖ Viktorsson, M Gabrielsen, N Kumarachandran, I Sylte, P Rongved, ... Steroids 118, 119-127, 2017 | 8 | 2017 |
Zinc-chelating compounds as inhibitors of human and bacterial zinc metalloproteases F Rahman, I Wushur, N Malla, OAH Åstrand, P Rongved, JO Winberg, ... Molecules 27 (1), 56, 2021 | 6 | 2021 |
Synthesis, in vitro and in vivo biological evaluation of new oxysterols as modulators of the liver X receptors OAH Åstrand, EÖ Viktorsson, AL Kristensen, D Ekeberg, ... The Journal of steroid biochemistry and molecular biology 165, 323-330, 2017 | 6 | 2017 |
Synthesis and initial biological evaluation of new mimics of the LXR-modulator 22 (S)-hydroxycholesterol OAH Åstrand, M Sandberg, I Sylte, CH Görbitz, GH Thoresen, ET Kase, ... Bioorganic & Medicinal Chemistry 22 (1), 643-650, 2014 | 6 | 2014 |
Inhibitors of metallo-beta-lactamase (MBL) comprising a zinc chelating moiety P Rongved, OAH Åstrand, A Bayer, HS Leiros, Ø Samuelsen, ... US Patent 10,227,327, 2019 | 1 | 2019 |
Compounds SO DØSKELAND, P RONGVED, L Herfindal, M Le Borgne, ... | 1 | 2015 |
Crystal structure of (S)-2-[(3S, 8S, 9S, 10R, 13S, 14S, 17R)-3-hydroxy-10, 13-dimethyl-2, 3, 4, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17-tetradecahydro-1H-cyclopenta [a … EØ Viktorsson, OAH Åstrand, RS Haseeb, CH Görbitz, P Rongved Acta Crystallographica Section E: Crystallographic Communications 71 (3 …, 2015 | 1 | 2015 |
(2S, 3S)-2, 6-Dimethylheptane-1, 3-diol, the oxygenated side chain of 22 (S)-hydroxycholestrol, and its synthetic precursor (R)-4-benzyl-3-[(2R, 3S)-3-hydroxy-2, 6 … OA Høgmoen Åstrand, Z Iqbal, M Sandberg, ET Kase, CH Görbitz, ... Acta Crystallographica Section C: Crystal Structure Communications 69 (6 …, 2013 | 1 | 2013 |
Substituted phenazines and methods of treating cancer and bacterial diseases P Rongved, OAH Åstrand, EØ Viktorsson, Ø Samuelson, A Heikal, ... US Patent 11,958,842, 2024 | | 2024 |