Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response D Sharon, S Cathelin, S Mirali, JM Di Trani, DJ Yanofsky, KA Keon, ... Science translational medicine 11 (516), eaax2863, 2019 | 153 | 2019 |
Shake-it-off: a simple ultrasonic cryo-EM specimen-preparation device JL Rubinstein, H Guo, ZA Ripstein, A Haydaroglu, A Au, CM Yip, ... Acta Crystallographica Section D: Structural Biology 75 (12), 1063-1070, 2019 | 72 | 2019 |
Rapid measurement of inhibitor binding kinetics by isothermal titration calorimetry JM Di Trani, S De Cesco, R O’Leary, J Plescia, CJ do Nascimento, ... Nature communications 9 (1), 893, 2018 | 64 | 2018 |
Cryo-EM structure and kinetics reveal electron transfer by 2D diffusion of cytochrome c in the yeast III-IV respiratory supercomplex A Moe, J Di Trani, JL Rubinstein, P Brzezinski Proceedings of the National Academy of Sciences 118 (11), e2021157118, 2021 | 56 | 2021 |
Efficient and rapid mechanochemical assembly of platinum (II) squares for guanine quadruplex targeting A Garci, KJ Castor, J Fakhoury, JL Do, J Di Trani, P Chidchob, RS Stein, ... Journal of the American Chemical Society 139 (46), 16913-16922, 2017 | 50 | 2017 |
Measuring rapid time-scale reaction kinetics using isothermal titration calorimetry JM Di Trani, N Moitessier, AK Mittermaier Analytical chemistry 89 (13), 7022-7030, 2017 | 42 | 2017 |
Structure of mycobacterial CIII2CIV2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203) DJ Yanofsky, JM Di Trani, S Krol, R Abdelaziz, SA Bueler, P Imming, ... Elife 10, e71959, 2021 | 27 | 2021 |
Exploring the role of post‐translational modifications in regulating α‐synuclein interactions by studying the effects of phosphorylation on nanobody binding F El Turk, E De Genst, T Guilliams, B Fauvet, M Hejjaoui, J Di Trani, ... Protein Science 27 (7), 1262-1274, 2018 | 26 | 2018 |
Complete kinetic characterization of enzyme inhibition in a single isothermal titration calorimetric experiment JM Di Trani, N Moitessier, AK Mittermaier Analytical chemistry 90 (14), 8430-8435, 2018 | 23 | 2018 |
Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III JM Di Trani, Z Liu, L Whitesell, P Brzezinski, LE Cowen, JL Rubinstein Structure 30 (1), 129-138. e4, 2021 | 22 | 2021 |
Integrated synthetic, biophysical, and computational investigations of covalent inhibitors of prolyl oligopeptidase and fibroblast activation protein α J Plescia, S De Cesco, MB Patrascu, J Kurian, J Di Trani, C Dufresne, ... Journal of Medicinal Chemistry 62 (17), 7874-7884, 2019 | 15 | 2019 |
Inhibition and activation of kinases by reaction products: a reporter-free assay Y Wang, J Guan, JM Di Trani, K Auclair, AK Mittermaier Analytical Chemistry 91 (18), 11803-11811, 2019 | 12 | 2019 |
Structural basis of mammalian complex IV inhibition by steroids JM Di Trani, A Moe, D Riepl, P Saura, VRI Kaila, P Brzezinski, ... Proceedings of the National Academy of Sciences 119 (30), e2205228119, 2022 | 7 | 2022 |
Conformational plasticity surrounding the active site of NADH oxidase from Thermus thermophilus T Miletti, J Di Trani, LC Jr. Levros, A Mittermaier Protein Science 24 (7), 1114-1128, 2015 | 7 | 2015 |
Flexible client-dependent cages in the assembly landscape of the periplasmic protease-chaperone DegP RW Harkness, ZA Ripstein, JM Di Trani, LE Kay Journal of the American Chemical Society 145 (24), 13015-13026, 2023 | 4 | 2023 |
High-resolution electron cryomicroscopy of V-ATPase in native synaptic vesicles CE Coupland, R Karimi, SA Bueler, Y Liang, GM Courbon, JM Di Trani, ... Science, eadp5577, 2024 | 2 | 2024 |
Structure of the bc1–cbb3 respiratory supercomplex from Pseudomonas aeruginosa JM Di Trani, AA Gheorghita, M Turner, P Brzezinski, P Ädelroth, S Vahidi, ... Proceedings of the National Academy of Sciences 120 (40), e2307093120, 2023 | 2 | 2023 |
Measuring enzyme kinetics using isothermal titration calorimetry JM Di Trani McGill University (Canada), 2019 | 2 | 2019 |
High resolution cryo-EM of V-ATPase in native synaptic vesicles CE Coupland, R Karimi, SA Bueler, Y Liang, GM Courbon, JM Di Trani, ... bioRxiv, 2024.04. 01.587493, 2024 | 1 | 2024 |
Imidazopyridine Amides: Synthesis, Mycobacterium smegmatis CIII2CIV2 Supercomplex Binding, and In Vitro Antimycobacterial Activity R Abdelaziz, JM Di Trani, H Sahile, L Mann, A Richter, Z Liu, SA Bueler, ... ACS omega 8 (21), 19081-19098, 2023 | 1 | 2023 |