Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans LA Herndon, PJ Schmeissner, JM Dudaronek, PA Brown, KM Listner, ... Nature 419 (6909), 808-814, 2002 | 1314 | 2002 |
A role for autophagy in the extension of lifespan by dietary restriction in C. elegans M Hansen, A Chandra, LL Mitic, B Onken, M Driscoll, C Kenyon PLoS genetics 4 (2), e24, 2008 | 855 | 2008 |
Metformin induces a dietary restriction–like state and the oxidative stress response to extend C. elegans healthspan via AMPK, LKB1, and SKN-1 B Onken, M Driscoll PloS one 5 (1), e8758, 2010 | 770 | 2010 |
Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes N Tavernarakis, SL Wang, M Dorovkov, A Ryazanov, M Driscoll Nature genetics 24 (2), 180-183, 2000 | 657 | 2000 |
Mechanosensory signalling in C. elegans mediated by the GLR-1 glutamate receptor AV Maricq, E Peckol, M Driscoll, CI Bargmann Nature 378 (6552), 78-81, 1995 | 419 | 1995 |
Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans P Syntichaki, K Xu, M Driscoll, N Tavernarakis Nature 419 (6910), 939-944, 2002 | 376 | 2002 |
C. elegans neurons jettison protein aggregates and mitochondria under neurotoxic stress I Melentijevic, ML Toth, ML Arnold, RJ Guasp, G Harinath, KC Nguyen, ... Nature 542 (7641), 367-371, 2017 | 351 | 2017 |
In vivo imaging of C. elegans mechanosensory neurons demonstrates a specific role for the MEC-4 channel in the process of gentle touch sensation H Suzuki, R Kerr, L Bianchi, C Frøkjær-Jensen, D Slone, J Xue, ... Neuron 39 (6), 1005-1017, 2003 | 344 | 2003 |
In vivo spectrofluorimetry reveals endogenous biomarkers that report healthspan and dietary restriction in Caenorhabditis elegans B Gerstbrein, G Stamatas, N Kollias, M Driscoll Aging cell 4 (3), 127-137, 2005 | 343 | 2005 |
Necrotic cell death in C. elegans requires the function of calreticulin and regulators of Ca2+ release from the endoplasmic reticulum K Xu, N Tavernarakis, M Driscoll Neuron 31 (6), 957-971, 2001 | 333 | 2001 |
The SPFH domain: implicated in regulating targeted protein turnover in stomatins and other membrane-associated proteins N Tavernarakis, M Driscoll, NC Kyrpides Trends in biochemical sciences 24 (11), 425-427, 1999 | 304 | 1999 |
Genetic and molecular analysis of a Caenorhabditis elegans beta-tubulin that conveys benzimidazole sensitivity. M Driscoll, E Dean, E Reilly, E Bergholz, M Chalfie The Journal of cell biology 109 (6), 2993-3003, 1989 | 304 | 1989 |
MOLECULAR MODELING OF MECHANOTRANSDUCTION IN THE NEMATODE CAENORHABDITIS ELEGANS N Tavernarakis and, M Driscoll Annual Review of Physiology 59 (1), 659-689, 1997 | 285 | 1997 |
Specific roles for DEG/ENaC and TRP channels in touch and thermosensation in C. elegans nociceptors M Chatzigeorgiou, S Yoo, JD Watson, WH Lee, WC Spencer, KS Kindt, ... Nature neuroscience 13 (7), 861-868, 2010 | 284 | 2010 |
A transmembrane domain of the putative channel subunit MEC-4 influences mechanotransduction and neurodegeneration in C. elegans K Hong, M Driscoll Nature 367 (6462), 470-473, 1994 | 263 | 1994 |
unc-8, a DEG/ENaC family member, encodes a subunit of a candidate mechanically gated channel that modulates C. elegans locomotion N Tavernarakis, W Shreffler, S Wang, M Driscoll Neuron 18 (1), 107-119, 1997 | 245 | 1997 |
A novel MitoTimer reporter gene for mitochondrial content, structure, stress, and damage in vivo RC Laker, P Xu, KA Ryall, A Sujkowski, BM Kenwood, KH Chain, ... Journal of Biological Chemistry 289 (17), 12005-12015, 2014 | 241 | 2014 |
Sequence relationships among C. elegans, D. melanogaster and human microRNAs highlight the extensive conservation of microRNAs in biology C Ibáñez-Ventoso, M Vora, M Driscoll PloS one 3 (7), e2818, 2008 | 233 | 2008 |
Modulated microRNA expression during adult lifespan in Caenorhabditis elegans C Ibáñez‐Ventoso, M Yang, S Guo, H Robins, RW Padgett, M Driscoll Aging cell 5 (3), 235-246, 2006 | 231 | 2006 |
Dying for a cause: invertebrate genetics takes on human neurodegeneration M Driscoll, B Gerstbrein Nature Reviews Genetics 4 (3), 181-194, 2003 | 228 | 2003 |