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Zhiyu Dai
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Prolyl-4 hydroxylase 2 (PHD2) deficiency in endothelial cells and hematopoietic cells induces obliterative vascular remodeling and severe pulmonary arterial hypertension in …
Z Dai, M Li, J Wharton, MM Zhu, YY Zhao
Circulation 133 (24), 2447-2458, 2016
2332016
Endothelial cells in the pathogenesis of pulmonary arterial hypertension
CE Evans, ND Cober, Z Dai, DJ Stewart, YY Zhao
European Respiratory Journal 58 (3), 2021
1832021
Therapeutic targeting of vascular remodeling and right heart failure in pulmonary arterial hypertension with a HIF-2α inhibitor
Z Dai, MM Zhu, Y Peng, N Machireddy, CE Evans, R Machado, X Zhang, ...
American journal of respiratory and critical care medicine 198 (11), 1423-1434, 2018
1512018
Endothelial and smooth muscle cell interaction via FoxM1 signaling mediates vascular remodeling and pulmonary hypertension
Z Dai, MM Zhu, Y Peng, H Jin, N Machireddy, Z Qian, X Zhang, YY Zhao
American journal of respiratory and critical care medicine 198 (6), 788-802, 2018
1342018
High levels of pigment epithelium–derived factor in diabetes impair wound healing through suppression of Wnt signaling
W Qi, C Yang, Z Dai, D Che, J Feng, Y Mao, R Cheng, Z Wang, X He, ...
Diabetes 64 (4), 1407-1419, 2015
1202015
High metastaticgastric and breast cancer cells consume oleic acid in an AMPK dependent manner
S Li, T Zhou, C Li, Z Dai, D Che, Y Yao, L Li, J Ma, X Yang, G Gao
PloS one 9 (5), e97330, 2014
1122014
Endothelial p110γPI3K mediates endothelial regeneration and vascular repair after inflammatory vascular injury
X Huang, Z Dai, L Cai, K Sun, J Cho, KH Albertine, AB Malik, ...
Circulation 133 (11), 1093-1103, 2016
722016
Pigment epithelium-derived factor (PEDF) inhibits breast cancer metastasis by down-regulating fibronectin
H Hong, T Zhou, S Fang, M Jia, Z Xu, Z Dai, C Li, S Li, L Li, T Zhang, W Qi, ...
Breast cancer research and treatment 148, 61-72, 2014
712014
Dual regulation of adipose triglyceride lipase by pigment epithelium-derived factor: a novel mechanistic insight into progressive obesity
Z Dai, W Qi, C Li, J Lu, Y Mao, Y Yao, L Li, T Zhang, H Hong, S Li, T Zhou, ...
Molecular and cellular endocrinology 377 (1-2), 123-134, 2013
492013
Endothelial FoxM1 mediates bone marrow progenitor cell-induced vascular repair and resolution of inflammation following inflammatory lung injury
YD Zhao, X Huang, F Yi, Z Dai, Z Qian, C Tiruppathi, K Tran, YY Zhao
Stem Cells 32 (7), 1855-1864, 2014
432014
Plasminogen kringle 5 induces endothelial cell apoptosis by triggering a voltage-dependent anion channel 1 (VDAC1) positive feedback loop
L Li, YC Yao, XQ Gu, D Che, CQ Ma, ZY Dai, C Li, T Zhou, WB Cai, ...
Journal of Biological Chemistry 289 (47), 32628-32638, 2014
422014
Plasminogen K5 activates mitochondrial apoptosis pathway in endothelial cells by regulating Bak and Bcl-xL subcellular distribution
X Gu, Y Yao, R Cheng, Y Zhang, Z Dai, G Wan, Z Yang, W Cai, G Gao, ...
Apoptosis 16, 846-855, 2011
422011
Loss of caveolin-1 and adiponectin induces severe inflammatory lung injury following LPS challenge through excessive oxidative/nitrative stress
L Cai, F Yi, Z Dai, X Huang, YD Zhao, MK Mirza, J Xu, SM Vogel, YY Zhao
American Journal of Physiology-Lung Cellular and Molecular Physiology 306 (6 …, 2014
412014
SERPINA 3 K induces apoptosis in human colorectal cancer cells via activating the F as/F as L/caspase‐8 signaling pathway
Y Yao, L Li, X Huang, X Gu, Z Xu, Y Zhang, L Huang, S Li, Z Dai, C Li, ...
The FEBS Journal 280 (14), 3244-3255, 2013
372013
Pigment epithelial-derived factor (PEDF)-triggered lung cancer cell apoptosis relies on p53 protein-driven Fas ligand (Fas-L) up-regulation and Fas protein cell surface …
L Li, YC Yao, SH Fang, CQ Ma, Y Cen, ZM Xu, ZY Dai, C Li, S Li, T Zhang, ...
Journal of Biological Chemistry 289 (44), 30785-30799, 2014
352014
Pigment epithelium-derived factor gene loaded in cRGD–PEG–PEI suppresses colorectal cancer growth by targeting endothelial cells
L Li, J Yang, WW Wang, YC Yao, SH Fang, ZY Dai, HH Hong, X Yang, ...
International journal of pharmaceutics 438 (1-2), 1-10, 2012
292012
Kallikrein‐binding protein inhibits LPS‐induced TNF‐α by upregulating SOCS3 expression
Z Dai, L Lu, Z Yang, Y Mao, J Lu, C Li, W Qi, Y Chen, Y Yao, L Li, S Chen, ...
Journal of cellular biochemistry 114 (5), 1020-1028, 2013
272013
Endothelial autocrine signaling through cxcl12/cxcr4/foxm1 axis contributes to severe pulmonary arterial hypertension
D Yi, B Liu, T Wang, Q Liao, MM Zhu, YY Zhao, Z Dai
International journal of molecular sciences 22 (6), 3182, 2021
252021
Deficiency of pigment epithelium-derived factor in nasopharyngeal carcinoma cells triggers the epithelial–mesenchymal transition and metastasis
T Zhang, P Yin, Z Zhang, B Xu, D Che, Z Dai, C Dong, P Jiang, H Hong, ...
Cell Death & Disease 8 (6), e2838-e2838, 2017
242017
Discovery of a murine model of clinical PAH: mission impossible?
Z Dai, YY Zhao
Trends in cardiovascular medicine 27 (4), 229-236, 2017
222017
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