Calmodulin Is Essential for Cardiac IKS Channel Gating and Assembly: Impaired Function in Long-QT Mutations L Shamgar, L Ma, N Schmitt, Y Haitin, A Peretz, R Wiener, J Hirsch, ... Circulation research 98 (8), 1055-1063, 2006 | 243 | 2006 |
The C‐terminus of Kv7 channels: a multifunctional module Y Haitin, B Attali The Journal of physiology 586 (7), 1803-1810, 2008 | 183 | 2008 |
The KCNQ1 (Kv7. 1) COOH terminus, a multitiered scaffold for subunit assembly and protein interaction R Wiener, Y Haitin, L Shamgar, MC Fernández-Alonso, A Martos, ... Journal of Biological Chemistry 283 (9), 5815-5830, 2008 | 161 | 2008 |
The structural mechanism of KCNH-channel regulation by the eag domain Y Haitin, AE Carlson, WN Zagotta Nature 501 (7467), 444-448, 2013 | 122 | 2013 |
Targeting the voltage sensor of Kv7. 2 voltage-gated K+ channels with a new gating-modifier A Peretz, L Pell, Y Gofman, Y Haitin, L Shamgar, E Patrich, P Kornilov, ... Proceedings of the National Academy of Sciences 107 (35), 15637-15642, 2010 | 109 | 2010 |
Molecular mechanism for 3: 1 subunit stoichiometry of rod cyclic nucleotide-gated ion channels NG Shuart, Y Haitin, SS Camp, KD Black, WN Zagotta Nature communications 2 (1), 457, 2011 | 99 | 2011 |
CryoEM structure of a prokaryotic cyclic nucleotide-gated ion channel ZM James, AJ Borst, Y Haitin, B Frenz, F DiMaio, WN Zagotta, D Veesler Proceedings of the National Academy of Sciences 114 (17), 4430-4435, 2017 | 65 | 2017 |
Competition of calcified calmodulin N lobe and PIP2 to an LQT mutation site in Kv7. 1 channel WS Tobelaim, M Dvir, G Lebel, M Cui, T Buki, A Peretz, M Marom, Y Haitin, ... Proceedings of the National Academy of Sciences 114 (5), E869-E878, 2017 | 63 | 2017 |
Long QT mutations at the interface between KCNQ1 helix C and KCNE1 disrupt IKS regulation by PKA and PIP2 M Dvir, R Strulovich, D Sachyani, I Ben-Tal Cohen, Y Haitin, C Dessauer, ... Journal of cell science 127 (18), 3943-3955, 2014 | 55 | 2014 |
Intracellular domains interactions and gated motions of IKS potassium channel subunits Y Haitin, R Wiener, D Shaham, A Peretz, EBT Cohen, L Shamgar, ... The EMBO journal 28 (14), 1994-2005, 2009 | 54 | 2009 |
KCNE1 constrains the voltage sensor of Kv7. 1 K+ channels L Shamgar, Y Haitin, I Yisharel, E Malka, H Schottelndreier, A Peretz, ... PLoS One 3 (4), e1943, 2008 | 53 | 2008 |
Recent molecular insights from mutated IKS channels in cardiac arrhythmia M Dvir, A Peretz, Y Haitin, B Attali Current opinion in pharmacology 15, 74-82, 2014 | 43 | 2014 |
Ca2+-Calmodulin and PIP2 interactions at the proximal C-terminus of Kv7 channels WS Tobelaim, M Dvir, G Lebel, M Cui, T Buki, A Peretz, M Marom, Y Haitin, ... Channels 11 (6), 686-695, 2017 | 38 | 2017 |
KCNQ1 channels do not undergo concerted but sequential gating transitions in both the absence and the presence of KCNE1 protein E Meisel, M Dvir, Y Haitin, M Giladi, A Peretz, B Attali Journal of Biological Chemistry 287 (41), 34212-34224, 2012 | 36 | 2012 |
S1 constrains S4 in the voltage sensor domain of Kv7. 1 K+ channels Y Haitin, I Yisharel, E Malka, L Shamgar, H Schottelndreier, A Peretz, ... PLoS One 3 (4), e1935, 2008 | 33 | 2008 |
Structure-based dynamic arrays in regulatory domains of sodium-calcium exchanger (NCX) isoforms M Giladi, SY Lee, Y Ariely, Y Teldan, R Granit, R Strulovich, Y Haitin, ... Scientific Reports 7 (1), 993, 2017 | 30 | 2017 |
Structural basis of heterotetrameric assembly and disease mutations in the human cis-prenyltransferase complex ML Bar-El, P Vaňková, A Yeheskel, L Simhaev, H Engel, P Man, Y Haitin, ... Nature Communications 11 (1), 5273, 2020 | 26 | 2020 |
Ultrasensitive chemiluminescent neuraminidase probe for rapid screening and identification of small-molecules with antiviral activity against influenza A virus in mammalian cells O Shelef, S Gutkin, D Feder, A Ben-Bassat, M Mandelboim, Y Haitin, ... Chemical Science 13 (42), 12348-12357, 2022 | 20 | 2022 |
Trans‐binding of UFM1 to UBA5 stimulates UBA5 homodimerization and ATP binding B Mashahreh, F Hassouna, N Soudah, E Cohen‐Kfir, R Strulovich, ... The FASEB Journal 32 (5), 2794-2802, 2018 | 19 | 2018 |
Inherent flexibility of CLIC6 revealed by crystallographic and solution studies A Ferofontov, R Strulovich, M Marom, M Giladi, Y Haitin Scientific reports 8 (1), 6882, 2018 | 18 | 2018 |