A clinical trial to maintain glycemic control in youth with type 2 diabetes TODAY Study Group New England Journal of Medicine 366 (24), 2247-2256, 2012 | 984 | 2012 |
Genome-wide association analysis reveals a SOD1 mutation in canine degenerative myelopathy that resembles amyotrophic lateral sclerosis T Awano, GS Johnson, CM Wade, ML Katz, GC Johnson, JF Taylor, ... Proceedings of the National Academy of Sciences 106 (8), 2794-2799, 2009 | 337 | 2009 |
Bottlenecks and selective sweeps during domestication have increased deleterious genetic variation in dogs CD Marsden, D Ortega-Del Vecchyo, DP O’Brien, JF Taylor, O Ramirez, ... Proceedings of the National Academy of Sciences 113 (1), 152-157, 2016 | 326 | 2016 |
A mutation in the cathepsin D gene (CTSD) in American Bulldogs with neuronal ceroid lipofuscinosis T Awano, ML Katz, DP O’Brien, JF Taylor, J Evans, S Khan, I Sohar, ... Molecular genetics and metabolism 87 (4), 341-348, 2006 | 158 | 2006 |
A frame shift mutation in canine TPP1 (the ortholog of human CLN2) in a juvenile Dachshund with neuronal ceroid lipofuscinosis T Awano, ML Katz, DP O’Brien, I Sohar, P Lobel, JR Coates, S Khan, ... Molecular Genetics and Metabolism 89 (3), 254-260, 2006 | 147 | 2006 |
A truncating mutation in ATP13A2 is responsible for adult-onset neuronal ceroid lipofuscinosis in Tibetan terriers FHG Farias, R Zeng, GS Johnson, FA Wininger, JF Taylor, RD Schnabel, ... Neurobiology of disease 42 (3), 468-474, 2011 | 144 | 2011 |
Clinical characteristics and inheritance of idiopathic epilepsy in Vizslas EE Patterson, JR Mickelson, Y Da, MC Roberts, AS McVey, DP O'Brien, ... Journal of veterinary internal medicine 17 (3), 319-325, 2003 | 126 | 2003 |
Breed Distribution of SOD1 Alleles Previously Associated with Canine Degenerative Myelopathy R Zeng, JR Coates, GC Johnson, L Hansen, T Awano, A Kolicheski, ... Journal of veterinary internal medicine 28 (2), 515-521, 2014 | 123 | 2014 |
Clinical characterization of a familial degenerative myelopathy in Pembroke Welsh Corgi dogs JR Coates, PA March, M Oglesbee, CG Ruaux, NJ Olby, RD Berghaus, ... Journal of Veterinary Internal Medicine 21 (6), 1323-1331, 2007 | 106 | 2007 |
Clinical description and mode of inheritance of idiopathic epilepsy in English springer spaniels EE Patterson, PJ Armstrong, DP O'Brien, MC Roberts, GS Johnson, ... Journal of the American Veterinary Medical Association 226 (1), 54-58, 2005 | 106 | 2005 |
A mutation in canine PPT1 causes early onset neuronal ceroid lipofuscinosis in a Dachshund DN Sanders, FH Farias, GS Johnson, V Chiang, JR Cook, DP O’Brien, ... Molecular genetics and metabolism 100 (4), 349-356, 2010 | 86 | 2010 |
A Homozygous KCNJ10 Mutation in Jack Russell Terriers and Related Breeds with Spinocerebellar Ataxia with Myokymia, Seizures, or Both D Gilliam, DP O'brien, JR Coates, GS Johnson, GC Johnson, ... Journal of veterinary internal medicine 28 (3), 871-877, 2014 | 82 | 2014 |
Cerebellar cortical degeneration in adult American Staffordshire Terriers N Olby, S Blot, JL Thibaud, J Phillips, DP O'Brien, J Burr, J Berg, T Brown, ... Journal of Veterinary Internal Medicine 18 (2), 201-208, 2004 | 81 | 2004 |
Lapaquistat acetate: development of a squalene synthase inhibitor for the treatment of hypercholesterolemia EA Stein, H Bays, D O'Brien, J Pedicano, E Piper, A Spezzi Circulation 123 (18), 1974-1985, 2011 | 80 | 2011 |
Myelinolysis after correction of hyponatremia in two dogs DP O'Brien, RA Kroll, GC Johnson, SJ Covert, MJ Nelson Journal of Veterinary Internal Medicine 8 (1), 40-48, 1994 | 80 | 1994 |
A Missense Mutation in Canine CLN6 in an Australian Shepherd with Neuronal Ceroid Lipofuscinosis ML Katz, FH Farias, DN Sanders, R Zeng, S Khan, GS Johnson, ... BioMed Research International 2011 (1), 198042, 2011 | 79 | 2011 |
Degenerative myelopathy in 18 Pembroke Welsh corgi dogs PA March, JR Coates, RJ Abyad, DA Williams, DP O'brien, NJ Olby, ... Veterinary pathology 46 (2), 241-250, 2009 | 75 | 2009 |
Inhibition of non-dopamine cells in the ventral tegmental area by benzodiazepines: relationship to A10 dopamine cell activity DP O'Brien, FJ White European journal of pharmacology 142 (3), 343-354, 1987 | 72 | 1987 |
Laminin α2 (merosin)-deficient muscular dystrophy and demyelinating neuropathy in two cats DP O'Brien, GC Johnson, LA Liu, LT Guo, E Engvall, HC Powell, ... Journal of the neurological sciences 189 (1-2), 37-43, 2001 | 69 | 2001 |
Regional anesthesia of the infraorbital and inferior alveolar nerves during noninvasive tooth pulp stimulation in halothane-anesthetized dogs ME Gross, ER Pope, D O’Brien, JR Dodam, J Polkow-Haight Journal of the American Veterinary Medical Association 211 (11), 1403-1405, 1997 | 67 | 1997 |