Attenuating the p53 pathway in human cancers: many means to the same end AR Wasylishen, G Lozano Cold Spring Harbor perspectives in medicine 6 (8), a026211, 2016 | 129 | 2016 |
Tumor cell kill by c-MYC depletion: role of MYC-regulated genes that control DNA double-strand break repair KR Luoto, AX Meng, AR Wasylishen, H Zhao, CL Coackley, LZ Penn, ... Cancer research 70 (21), 8748-8759, 2010 | 106 | 2010 |
Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis MP Kim, X Li, J Deng, Y Zhang, B Dai, KL Allton, TG Hughes, C Siangco, ... Cancer discovery 11 (8), 2094-2111, 2021 | 93 | 2021 |
Myc: the beauty and the beast AR Wasylishen, LZ Penn Genes & cancer 1 (6), 532-541, 2010 | 93 | 2010 |
Pla2g16 phospholipase mediates gain-of-function activities of mutant p53 S Xiong, H Tu, M Kollareddy, V Pant, Q Li, Y Zhang, JG Jackson, YA Suh, ... Proceedings of the National Academy of Sciences 111 (30), 11145-11150, 2014 | 88 | 2014 |
Identifying molecular features that distinguish fluvastatin-sensitive breast tumor cells CA Goard, M Chan-Seng-Yue, PJ Mullen, AD Quiroga, AR Wasylishen, ... Breast cancer research and treatment 143, 301-312, 2014 | 74 | 2014 |
Inhibition of the sodium/potassium ATPase impairs N-glycan expression and function RB Zavareh, KS Lau, R Hurren, A Datti, DJ Ashline, M Gronda, P Cheung, ... Cancer research 68 (16), 6688-6697, 2008 | 70 | 2008 |
CRISPR/Cas9 can mediate high-efficiency off-target mutations in mice in vivo NK Aryal, AR Wasylishen, G Lozano Cell death & disease 9 (11), 1099, 2018 | 63 | 2018 |
MYC phosphorylation at novel regulatory regions suppresses transforming activity AR Wasylishen, M Chan-Seng-Yue, C Bros, D Dingar, WB Tu, M Kalkat, ... Cancer research 73 (21), 6504-6515, 2013 | 42 | 2013 |
New model systems provide insights into Myc-induced transformation AR Wasylishen, A Stojanova, S Oliveri, AC Rust, AD Schimmer, LZ Penn Oncogene 30 (34), 3727-3734, 2011 | 39 | 2011 |
p53 drives a transcriptional program that elicits a non-cell-autonomous response and alters cell state in vivo SM Moyer, AR Wasylishen, Y Qi, N Fowlkes, X Su, G Lozano Proceedings of the National Academy of Sciences 117 (38), 23663-23673, 2020 | 35 | 2020 |
PLA2G16 promotes osteosarcoma metastasis and drug resistance via the MAPK pathway L Li, S Liang, AR Wasylishen, Y Zhang, X Yang, B Zhou, L Shan, X Han, ... Oncotarget 7 (14), 18021, 2016 | 32 | 2016 |
Daxx maintains endogenous retroviral silencing and restricts cellular plasticity in vivo AR Wasylishen, C Sun, SM Moyer, Y Qi, GP Chau, NK Aryal, F McAllister, ... Science Advances 6 (32), eaba8415, 2020 | 31 | 2020 |
Transient enhancement of p53 activity protects from radiation-induced gastrointestinal toxicity V Pant, S Xiong, AR Wasylishen, CA Larsson, NK Aryal, G Chau, ... Proceedings of the National Academy of Sciences 116 (35), 17429-17437, 2019 | 31 | 2019 |
Identification of c-MYC SUMOylation by mass spectrometry M Kalkat, PK Chan, AR Wasylishen, T Srikumar, SS Kim, R Ponzielli, ... PloS one 9 (12), e115337, 2014 | 22 | 2014 |
MYC activity is negatively regulated by a C-terminal lysine cluster AR Wasylishen, M Kalkat, SS Kim, A Pandyra, PK Chan, S Oliveri, ... Oncogene 33 (8), 1066-1072, 2014 | 19 | 2014 |
Constitutive Dicer1 phosphorylation accelerates metabolism and aging in vivo NK Aryal, V Pant, AR Wasylishen, J Parker-Thornburg, L Baseler, ... Proceedings of the National Academy of Sciences 116 (3), 960-969, 2019 | 17 | 2019 |
EGFR suppresses p53 function by promoting p53 binding to DNA-PKcs: a noncanonical regulatory axis between EGFR and wild-type p53 in glioblastoma J Ding, X Li, S Khan, C Zhang, F Gao, S Sen, AR Wasylishen, Y Zhao, ... Neuro-oncology 24 (10), 1712-1725, 2022 | 16 | 2022 |
Daxx Functions Are p53-Independent In Vivo AR Wasylishen, JS Estrella, V Pant, GP Chau, G Lozano Molecular Cancer Research 16 (10), 1523-1529, 2018 | 16 | 2018 |
Men1 maintains exocrine pancreas homeostasis in response to inflammation and oncogenic stress AR Wasylishen, C Sun, GP Chau, Y Qi, X Su, MP Kim, JS Estrella, ... Proceedings of the National Academy of Sciences 117 (12), 6622-6629, 2020 | 15 | 2020 |