关注
Zacary P. Germon
Zacary P. Germon
在 newcastle.edu.au 的电子邮件经过验证
标题
引用次数
引用次数
年份
The role of reactive oxygen species in acute myeloid leukaemia
JR Sillar, ZP Germon, GN De Iuliis, MD Dun
International journal of molecular sciences 20 (23), 6003, 2019
1252019
Preclinical and clinical evaluation of German-sourced ONC201 for the treatment of H3K27M-mutant diffuse intrinsic pontine glioma
RJ Duchatel, A Mannan, AS Woldu, T Hawtrey, PA Hindley, AM Douglas, ...
Neuro-oncology advances 3 (1), vdab169, 2021
392021
ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma
ER Jackson, RJ Duchatel, DE Staudt, ML Persson, A Mannan, S Yadavilli, ...
Cancer research 83 (14), 2421-2437, 2023
332023
Shwachman–Bodian–Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia
MD Dun, A Mannan, CJ Rigby, S Butler, HD Toop, D Beck, P Connerty, ...
Leukemia 34 (12), 3393-3397, 2020
182020
B-cell lymphoma 6 (BCL6): from master regulator of humoral immunity to oncogenic driver in pediatric cancers
T McLachlan, WC Matthews, ER Jackson, DE Staudt, AM Douglas, ...
Molecular Cancer Research 20 (12), 1711-1723, 2022
152022
Reactive oxygen species in acute lymphoblastic leukaemia: reducing radicals to refine responses
A Mannan, ZP Germon, J Chamberlain, JR Sillar, B Nixon, MD Dun
Antioxidants 10 (10), 1616, 2021
152021
Blockade of ROS production inhibits oncogenic signaling in acute myeloid leukemia and amplifies response to precision therapies
ZP Germon, JR Sillar, A Mannan, RJ Duchatel, D Staudt, HC Murray, ...
Science Signaling 16 (778), eabp9586, 2023
102023
PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma
RJ Duchatel, ER Jackson, SG Parackal, D Kiltschewskij, IJ Findlay, ...
The Journal of clinical investigation 134 (6), 2024
32024
Crosstalk between DNA methylation and hypoxia in acute myeloid leukaemia
S Humphries, DR Bond, ZP Germon, S Keely, AK Enjeti, MD Dun, HJ Lee
Clinical epigenetics 15 (1), 150, 2023
32023
Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection
DE Staudt, HC Murray, DA Skerrett-Byrne, ND Smith, MFB Jamaluddin, ...
Clinical Proteomics 19 (1), 48, 2022
32022
Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection (vol 19, 48, 2022)
DE Staudt, HC Murray, DA Skerrett-Byrne, ND Smith, MFB Jamaluddin, ...
CLINICAL PROTEOMICS 20 (1), 2023
12023
EXTH-36. COMBINING ONC201 AND PAXALISIB FOR THE TREATMENT OF DIFFUSE MIDLINE GLIOMA (DMG); THE PRECLINICAL RESULTS UNDERPINNING THE INTERNATIONAL PHASE II CLINICAL TRIAL …
E Jackson, R Duchatel, D Staudt, M Persson, A Mannan, S Yadavilli, ...
Neuro-Oncology 25 (Supplement_5), v232-v232, 2023
2023
EXTH-31. EXPLOITING THE GENETIC DEPENDENCY ON PI3K/MTOR SIGNALING FOR THE TREATMENT OF H3-ALTERED DIFFUSE MIDLINE GLIOMA
R Duchatel, E Jackson, S Parackal, C Sun, P Daniel, A Mannan, I Findlay, ...
Neuro-Oncology 25 (Supplement_5), v230-v231, 2023
2023
EXTH-12. PRECLINICAL AND CASE STUDY EXAMINATION OF THE COMBINATION OF THE CLPP AGONIST ONC201 WITH THE PI3K/AKT INHIBITOR PAXALISIB FOR THE TREATMENT OF DIFFUSE MIDLINE GLIOMA
E Jackson, R Duchatel, M Persson, A Mannan, S Yadavilli, S Parackal, ...
Neuro-Oncology 24 (Supplement_7), vii211-vii211, 2022
2022
DIPG-07. Preclinical and case study results underpinning the phase II clinical trial testing the combination of ONC201 and paxalisib for the treatment of patients with diffuse …
MD Dun, ER Jackson, RJ Duchatel, ML Persson, A Mannan, S Yadavilli, ...
Neuro-Oncology 24 (Supplement_1), i18-i19, 2022
2022
High-Throughput Global Phosphoproteomic Profiling Using Phospho Heavy-Labeled-Spiketide FAIMS Stepped-CV DDA (pHASED)
DE Staudt, HC Murray, DA Skerrett-Byrne, ND Smith, MF Jamaluddin, ...
bioRxiv, 2022.04. 22.489124, 2022
2022
Dun. MD Reactive Oxygen Species in Acute Lymphoblastic Leukaemia: Reducing Radicals to Refine Response. Antioxidants 2021, 10, 1616
A Mannan, ZP Germon, J Chamberlain, J Sillar, B Nixon
s Note: MDPI stays neu-tral with regard to jurisdictional claims in …, 2021
2021
Reactive oxygen species in FLT3-ITD+ acute myeloid leukemia contributes to oncogenic signaling and is a novel treatment target
ZP Germon, JR Sillar, A Mannan, R Duchatel, HC Murray, A Douglas, ...
Asia Pacific Journal of Clinical Oncology 16 (Suppl. 6), 25-26, 2020
2020
The use of low-THC cannabis and non-THC cannabinoids in the complementary treatment of acute myeloid leukemia (AML)
F Afrin, M Chi, A Woldu, R Duchatel, AM Douglas, Z Germon, DS Barreto, ...
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 16, 30-31, 2020
2020
Targeting oxidative stress in high-risk pediatric acute lymphoblastic leukemia
A Mannan, ZP Germon, J Sillar, RJ Duchatel, A Douglas, K McCarthy, ...
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 16, 30-30, 2020
2020
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