Blood-brain barrier disruption with focused ultrasound enhances delivery of chemotherapeutic drugs for glioblastoma treatment HL Liu, MY Hua, PY Chen, PC Chu, CH Pan, HW Yang, CY Huang, ... Radiology 255 (2), 415-425, 2010 | 454 | 2010 |
Magnetic resonance monitoring of focused ultrasound/magnetic nanoparticle targeting delivery of therapeutic agents to the brain HL Liu, MY Hua, HW Yang, CY Huang, PC Chu, JS Wu, IC Tseng, ... Proceedings of the National Academy of Sciences 107 (34), 15205-15210, 2010 | 442 | 2010 |
Focused ultrasound-induced blood–brain barrier opening to enhance temozolomide delivery for glioblastoma treatment: a preclinical study KC Wei, PC Chu, HYJ Wang, CY Huang, PY Chen, HC Tsai, YJ Lu, ... PloS one 8 (3), e58995, 2013 | 241 | 2013 |
Smart multifunctional hollow microspheres for the quick release of drugs in intracellular lysosomal compartments CJ Ke, TY Su, HL Chen, HL Liu, WL Chiang, PC Chu, Y Xia, HW Sung Angewandte Chemie International Edition 50 (35), 8086-8089, 2011 | 186 | 2011 |
Focused ultrasound enhances central nervous system delivery of bevacizumab for malignant glioma treatment HL Liu, PH Hsu, CY Lin, CW Huang, WY Chai, PC Chu, CY Huang, ... Radiology 281 (1), 99-108, 2016 | 166 | 2016 |
Novel magnetic/ultrasound focusing system enhances nanoparticle drug delivery for glioma treatment PY Chen, HL Liu, MY Hua, HW Yang, CY Huang, PC Chu, LA Lyu, ... Neuro-oncology 12 (10), 1050-1060, 2010 | 147 | 2010 |
Characterization of different microbubbles in assisting focused ultrasound-induced blood-brain barrier opening SK Wu, PC Chu, WY Chai, ST Kang, CH Tsai, CH Fan, CK Yeh, HL Liu Scientific reports 7 (1), 46689, 2017 | 141 | 2017 |
Focused ultrasound-induced blood-brain barrier opening: association with mechanical index and cavitation index analyzed by dynamic contrast-enhanced magnetic-resonance imaging PC Chu, WY Chai, CH Tsai, ST Kang, CK Yeh, HL Liu Scientific reports 6 (1), 33264, 2016 | 120 | 2016 |
Neuromodulation accompanying focused ultrasound-induced blood-brain barrier opening PC Chu, HL Liu, HY Lai, CY Lin, HC Tsai, YC Pei Scientific reports 5 (1), 15477, 2015 | 109 | 2015 |
Magnetic-resonance imaging for kinetic analysis of permeability changes during focused ultrasound-induced blood–brain barrier opening and brain drug delivery WY Chai, PC Chu, MY Tsai, YC Lin, JJ Wang, KC Wei, YY Wai, HL Liu Journal of Controlled Release 192, 1-9, 2014 | 68 | 2014 |
Cooperative dual-activity targeted nanomedicine for specific and effective prostate cancer therapy HW Yang, MY Hua, HL Liu, RY Tsai, CK Chuang, PC Chu, PY Wu, ... ACS nano 6 (2), 1795-1805, 2012 | 59 | 2012 |
Magnetic resonance imaging enhanced by superparamagnetic iron oxide particles: Usefulness for distinguishing between focused ultrasound‐induced blood–brain barrier disruption … HL Liu, PH Hsu, PC Chu, YY Wai, JC Chen, CR Shen, TC Yen, JJ Wang Journal of Magnetic Resonance Imaging: An Official Journal of the …, 2009 | 58 | 2009 |
Design and experimental evaluation of a 256-channel dual-frequency ultrasound phased-array system for transcranial blood–brain barrier opening and brain drug delivery HL Liu, CK Jan, PC Chu, JC Hong, PY Lee, JD Hsu, CC Lin, CY Huang, ... IEEE Transactions on Biomedical Engineering 61 (4), 1350-1360, 2014 | 47 | 2014 |
Pharmacodynamic analysis of magnetic resonance imaging‐monitored focused ultrasound‐induced blood‐brain barrier opening for drug delivery to brain tumors PC Chu, WY Chai, HY Hsieh, JJ Wang, SP Wey, CY Huang, KC Wei, ... BioMed research international 2013 (1), 627496, 2013 | 47 | 2013 |
Sufficient virus-neutralizing antibody in the central nerve system improves the survival of rabid rats PH Liao, HH Yang, PT Chou, MH Wang, PC Chu, HL Liu, LK Chen Journal of biomedical science 19, 1-10, 2012 | 26 | 2012 |
Image-guided focused-ultrasound CNS molecular delivery: an implementation via dynamic contrast-enhanced magnetic-resonance imaging WY Chai, PC Chu, CH Tsai, CY Lin, HW Yang, HY Lai, HL Liu Scientific reports 8 (1), 4151, 2018 | 16 | 2018 |
Pulsed-focused ultrasound provides long-term suppression of epileptiform bursts in the kainic acid-induced epilepsy rat model PC Chu, HY Yu, CC Lee, R Fisher, HL Liu Neurotherapeutics 19 (4), 1368-1380, 2022 | 14 | 2022 |
Weak ultrasound contributes to neuromodulatory effects in the rat motor cortex PC Chu, CS Huang, PK Chang, RS Chen, KT Chen, TH Hsieh, HL Liu International Journal of Molecular Sciences 24 (3), 2578, 2023 | 12 | 2023 |
Method for ultrasound-mediated delivery system to monitor molecular penetration HL Liu, KC Wei, PY Chen, PH Hsu, PC Chu, WY Chai, CY Lin US Patent 10,076,652, 2018 | 7 | 2018 |
Investigation of the Effect of Acoustic Pressure and Sonication Duration on Focused-Ultrasound Induced Blood-Brain Barrier Disruption PC Chu, MC Hsiao, YH Yang, JC Chen, HL Liu 13th International Conference on Biomedical Engineering: ICBME 2008 3–6 …, 2009 | 6 | 2009 |