Human non-neutralizing HIV-1 envelope monoclonal antibodies limit the number of founder viruses during SHIV mucosal infection in rhesus macaques S Santra, GD Tomaras, R Warrier, NI Nicely, HX Liao, J Pollara, P Liu, ... PLoS Pathog 11 (8), e1005042, 2015 | 164 | 2015 |
Evaluation of TLR agonists as potential mucosal adjuvants for HIV gp140 and tetanus toxoid in mice V Buffa, K Klein, L Fischetti, RJ Shattock PloS one 7 (12), e50529, 2012 | 67 | 2012 |
Characterization of a plant-produced recombinant human secretory IgA with broad neutralizing activity against HIV M Paul, R Reljic, K Klein, PMW Drake, C van Dolleweerd, M Pabst, ... mAbs 6 (6), 1585-1597, 2014 | 61 | 2014 |
Characterization of VRC01, a potent and broadly neutralizing anti‐HIV mAb, produced in transiently and stably transformed tobacco AYH Teh, D Maresch, K Klein, JKC Ma Plant biotechnology journal 12 (3), 300-311, 2014 | 53 | 2014 |
Neutralizing IgG at the portal of infection mediates protection against vaginal simian/human immunodeficiency virus challenge K Klein, RS Veazey, R Warrier, P Hraber, LA Doyle-Meyers, V Buffa, ... Journal of virology 87 (21), 11604-11616, 2013 | 50 | 2013 |
Pulmonary delivery of DNA vaccine constructs using deacylated PEI elicits immune responses and protects against viral challenge infection JFS Mann, PF McKay, S Arokiasamy, RK Patel, K Klein, RJ Shattock Journal of controlled release 170 (3), 452-459, 2013 | 45 | 2013 |
Enhanced immunogenicity of an HIV-1 DNA vaccine delivered with electroporation via combined intramuscular and intradermal routes JFS Mann, PF McKay, A Fiserova, K Klein, A Cope, P Rogers, J Swales, ... Journal of virology 88 (12), 6959-6969, 2014 | 39 | 2014 |
First Phase I human clinical trial of a killed whole-HIV-1 vaccine: demonstration of its safety and enhancement of anti-HIV antibody responses E Choi, CJ Michalski, SH Choo, GN Kim, E Banasikowska, S Lee, K Wu, ... Retrovirology 13 (1), 82, 2016 | 36 | 2016 |
Aggregate complexes of HIV-1 induced by multimeric antibodies DJ Stieh, DF King, K Klein, P Liu, X Shen, KK Hwang, G Ferrari, ... Retrovirology 11 (1), 78, 2014 | 35 | 2014 |
Eradication of HIV-1 latent reservoirs through therapeutic vaccination J Pankrac, K Klein, JFS Mann AIDS research and therapy 14 (1), 45, 2017 | 29 | 2017 |
Higher sequence diversity in the vaginal tract than in blood at early HIV-1 infection K Klein, G Nickel, I Nankya, F Kyeyune, K Demers, E Ndashimye, C Kwok, ... PLoS pathogens 14 (1), e1006754, 2018 | 27 | 2018 |
A “prime-pull” vaccine strategy has a modest effect on local and systemic antibody responses to HIV gp140 in mice JS Tregoning, V Buffa, A Oszmiana, K Klein, AA Walters, RJ Shattock PloS one 8 (11), e80559, 2013 | 25 | 2013 |
A heterogeneous human immunodeficiency virus-like particle (VLP) formulation produced by a novel vector system J Pankrac, K Klein, PF McKay, DFL King, K Bain, J Knapp, T Biru, ... NPJ vaccines 3 (1), 1-10, 2018 | 22 | 2018 |
Polymeric penetration enhancers promote humoral immune responses to mucosal vaccines K Klein, JFS Mann, P Rogers, RJ Shattock Journal of Controlled Release 183, 43-50, 2014 | 22 | 2014 |
Transferrin conjugation confers mucosal molecular targeting to a model HIV-1 trimeric gp140 vaccine antigen JFS Mann, D Stieh, K Klein, DSM de Stegmann, MP Cranage, ... Journal of Controlled Release 158 (2), 240-249, 2012 | 19 | 2012 |
Discrete partitioning of HIV-1 Env forms revealed by viral capture DJ Stieh, DF King, K Klein, Y Aldon, PF McKay, RJ Shattock Retrovirology 12 (1), 1-15, 2015 | 18 | 2015 |
Evaluation of mucosal adjuvants and immunization routes for the induction of systemic and mucosal humoral immune responses in macaques RS Veazey, A Siddiqui, K Klein, V Buffa, L Fischetti, L Doyle-Meyers, ... Human vaccines & immunotherapeutics 11 (12), 2913-2922, 2015 | 17 | 2015 |
Rational design of HIV vaccines and microbicides: report of the EUROPRISE network annual conference 2010 S Brinckmann, K Da Costa, MJ van Gils, D Hallengärd, K Klein, L Madeira, ... Journal of translational medicine 9 (1), 1-12, 2011 | 8 | 2011 |
Rational design of HIV vaccine and microbicides: report of the EUROPRISE annual conference B Wahren, P Biswas, M Borggren, A Coleman, K Da Costa, W De Haes, ... Journal of translational medicine 8 (1), 1-11, 2010 | 6 | 2010 |
An in vitro Model to Mimic Selection of Replication-Competent HIV-1 Intersubtype Recombination in Dual or Superinfected Patients BS Bagaya, M Tian, GC Nickel, JF Vega, Y Li, P He, K Klein, JFS Mann, ... Journal of molecular biology 429 (14), 2246-2264, 2017 | 5 | 2017 |