| In vivo discovery of immunotherapy targets in the tumour microenvironment P Zhou, DR Shaffer, DA Alvarez Arias, Y Nakazaki, W Pos, AJ Torres, ... Nature 506 (7486), 52-57, 2014 | 260 | 2014 |
| Crystal structure of the HLA-DM–HLA-DR1 complex defines mechanisms for rapid peptide selection W Pos, DK Sethi, MJ Call, MSED Schulze, AK Anders, J Pyrdol, ... Cell 151 (7), 1557-1568, 2012 | 189 | 2012 |
| Binding mode prediction of cytochrome P450 and thymidine kinase protein− ligand complexes by consideration of water and rescoring in automated docking C De Graaf, P Pospisil, W Pos, G Folkers, NPE Vermeulen Journal of medicinal chemistry 48 (7), 2308-2318, 2005 | 172 | 2005 |
| An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF W Pos, JTB Crawley, R Fijnheer, J Voorberg, DA Lane, BM Luken Blood, The Journal of the American Society of Hematology 115 (8), 1640-1649, 2010 | 165 | 2010 |
| Residues Arg568 and Phe592 contribute to an antigenic surface for anti-ADAMTS13 antibodies in the spacer domain W Pos, N Sorvillo, R Fijnheer, HB Feys, PHP Kaijen, G Vidarsson, ... haematologica 96 (11), 1670, 2011 | 107 | 2011 |
| Molecular mechanisms for contribution of MHC molecules to autoimmune diseases LM Sollid, W Pos, KW Wucherpfennig Current opinion in immunology 31, 24-30, 2014 | 99 | 2014 |
| VH1‐69 germline encoded antibodies directed towards ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura W Pos, BM Luken, EAM Turenhout, F Scheiflinger, JF Dong, R Fijnheer, ... Journal of thrombosis and haemostasis 7 (3), 421-428, 2009 | 86 | 2009 |
| Amino acid regions 572–579 and 657–666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP BM Luken, EAM Turenhout, PHP Kaijen, MJ Greuter, W Pos, ... Thrombosis and haemostasis 96 (09), 295-301, 2006 | 77 | 2006 |
| Mechanisms of peptide repertoire selection by HLA-DM W Pos, DK Sethi, KW Wucherpfennig Trends in immunology 34 (10), 495-501, 2013 | 66 | 2013 |
| The macrophage mannose receptor promotes uptake of ADAMTS13 by dendritic cells N Sorvillo, W Pos, LM van den Berg, R Fijnheer, L Martinez-Pomares, ... Blood, The Journal of the American Society of Hematology 119 (16), 3828-3835, 2012 | 58 | 2012 |
| Humoral immune response to ADAMTS13 in acquired thrombotic thrombocytopenic purpura W Pos, BM Luken, N Sorvillo, JAK Hovinga, J Voorberg Journal of thrombosis and haemostasis 9 (7), 1285-1291, 2011 | 48 | 2011 |
| Identification of N‐linked glycosylation and putative O‐fucosylation, C‐mannosylation sites in plasma derived ADAMTS13 N Sorvillo, PH Kaijen, M Matsumoto, Y Fujimura, C van der Zwaan, ... Journal of Thrombosis and Haemostasis 12 (5), 670-679, 2014 | 37 | 2014 |
| Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F W Oosterheert, KT Xenaki, V Neviani, W Pos, S Doulkeridou, ... Life Science Alliance 3 (11), 2020 | 22 | 2020 |
| AT1412, a patient-derived antibody in development for the treatment of CD9 positive precursor B-acute lymphoblastic leukemia G De Jong, SE Levie, R Schotte, W Pos, D Go, E Yasuda, M Cercel, ... Blood 134, 4461, 2019 | 2 | 2019 |
| 580P AT1412, a patient-derived CD9 antibody promotes tumour immune infiltration and induces tumour rejection R Schotte, J Villaudy, M Kedde, W Pos, K Wagner, D Go, C Fatmawati, ... Annals of Oncology 31, S492, 2020 | 1 | 2020 |
| 582P Preclinical development of AT1412, a patient derived CD9 antibody that does not induce thrombosis for treatment of precursor B ALL J Villaudy, R Schotte, G de Jong, V Neviani, W Pos, S Levie, E Yasuda, ... Annals of Oncology 31, S493, 2020 | 1 | 2020 |
| 14 A patient derived antibody targeting the tetraspanin CD9 inhibits tumour progression and metastasis R Schotte, J Villaudy, E Verdegaal, D Go, C Fatmawati, C Bru, ... ESMO Open 3, A6-A7, 2018 | 1 | 2018 |
| The role of MHC class II polymorphisms for DM-mediated peptide editing and autoimmunity S Haag, W Pos, J Pyrdol, SK Dougan, KW Wucherpfennig The Journal of Immunology 198 (1_Supplement), 156.24-156.24, 2017 | 1 | 2017 |
| C-Type Lectin Receptor Mediated Immune Recognition of ADAMTS13 Promotes HLA-DRB1* 11 Dependent Presentation of CUB1-2 Derived Peptides by Dendritic Cells N Sorvillo, SD van Haren, W Pos, E Herczenik, R Fijnheer, ... Blood, The Journal of the American Society of Hematology 118 (21), 196-196, 2011 | 1 | 2011 |
| Therapeutic anti-CD9 antibody H Spits, PMW Van Helden, R Schotte, POS Wouter, C Fatmawati, DM Go, ... US Patent 11,999,793, 2024 | | 2024 |
