Bcl-2 regulates a caspase-3/caspase-2 apoptotic cascade in cytosolic extracts E Swanton, P Savory, S Cosulich, P Clarke, P Woodman Oncogene 18 (10), 1781-1787, 1999 | 219 | 1999 |
Deubiquitinases regulate the activity of caspase-1 and interleukin-1β secretion via assembly of the inflammasome G Lopez-Castejon, NM Luheshi, V Compan, S High, RC Whitehead, ... Journal of Biological Chemistry 288 (4), 2721-2733, 2013 | 215 | 2013 |
Role of calnexin in the glycan‐independent quality control of proteolipid protein E Swanton, S High, P Woodman The EMBO journal, 2003 | 145 | 2003 |
Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum BCS Cross, C McKibbin, AC Callan, P Roboti, M Piacenti, C Rabu, ... Journal of cell science 122 (23), 4393-4400, 2009 | 127 | 2009 |
Protein folding and translocation across the endoplasmic reticulum membrane E Swanton, NJ Bulleid Molecular membrane biology 20 (2), 99-104, 2003 | 73 | 2003 |
Pak2 as a novel therapeutic target for cardioprotective endoplasmic reticulum stress response P Binder, S Wang, M Radu, M Zin, L Collins, S Khan, Y Li, K Sekeres, ... Circulation research 124 (5), 696-711, 2019 | 66 | 2019 |
Biosynthesis of the dystonia-associated AAA+ ATPase torsinA at the endoplasmic reticulum AC Callan, S Bunning, OT Jones, S High, E Swanton Biochemical Journal 401 (2), 607-612, 2007 | 65 | 2007 |
Mammalian OS-9 is upregulated in response to endoplasmic reticulum stress and facilitates ubiquitination of misfolded glycoproteins F Alcock, E Swanton Journal of molecular biology 385 (4), 1032-1042, 2009 | 63 | 2009 |
Increased intracellular proteolysis reduces disease severity in an ER stress–associated dwarfism LA Mullan, EJ Mularczyk, LH Kung, M Forouhan, JMA Wragg, R Goodacre, ... The Journal of clinical investigation 127 (10), 3861-3865, 2017 | 54 | 2017 |
Eeyarestatin compounds selectively enhance Sec61-mediated Ca2+ leakage from the endoplasmic reticulum I Gamayun, S O'Keefe, T Pick, MC Klein, D Nguyen, C McKibbin, ... Cell chemical biology 26 (4), 571-583. e6, 2019 | 52 | 2019 |
Inhibition of protein translocation at the endoplasmic reticulum promotes activation of the unfolded protein response C McKibbin, A Mares, M Piacenti, H Williams, P Roboti, M Puumalainen, ... Biochemical Journal 442 (3), 639-648, 2012 | 49 | 2012 |
Disease-associated mutations cause premature oligomerization of myelin proteolipid protein in the endoplasmic reticulum E Swanton, A Holland, S High, P Woodman Proceedings of the National Academy of Sciences 102 (12), 4342-4347, 2005 | 49 | 2005 |
The plasma membrane calcium pump in pancreatic cancer cells exhibiting the Warburg effect relies on glycolytic ATP AD James, W Patel, Z Butt, M Adiamah, R Dakhel, A Latif, C Uggenti, ... Journal of Biological Chemistry 290 (41), 24760-24771, 2015 | 43 | 2015 |
Differences in endoplasmic-reticulum quality control determine the cellular response to disease-associated mutants of proteolipid protein P Roboti, E Swanton, S High Journal of cell science 122 (21), 3942-3953, 2009 | 43 | 2009 |
Transmembrane domain quality control systems operate at the endoplasmic reticulum and Golgi apparatus K Briant, N Johnson, E Swanton PLoS One 12 (4), e0173924, 2017 | 40 | 2017 |
Eeyarestatin 1 interferes with both retrograde and anterograde intracellular trafficking pathways MO Aletrari, C McKibbin, H Williams, V Pawar, P Pietroni, JM Lord, ... PloS one 6 (7), e22713, 2011 | 37 | 2011 |
Human rabaptin-5 is selectively cleaved by caspase-3 during apoptosis E Swanton, N Bishop, P Woodman Journal of biological chemistry 274 (53), 37583-37590, 1999 | 35 | 1999 |
Restoration of mutant bestrophin-1 expression, localisation and function in a polarised epithelial cell model C Uggenti, K Briant, AK Streit, S Thomson, YH Koay, RA Baines, ... Disease models & mechanisms 9 (11), 1317-1328, 2016 | 31 | 2016 |
Formation and Turnover of NSF-and SNAP-containing “Fusion” Complexes Occur on Undocked, Clathrin-coated Vesicle–derived Membranes E Swanton, J Sheehan, N Bishop, S High, P Woodman Molecular biology of the cell 9 (7), 1633-1647, 1998 | 27 | 1998 |
ER targeting signals: more than meets the eye? E Swanton, S High Cell 127 (5), 877-879, 2006 | 18 | 2006 |