The SAGA deubiquitination module promotes DNA repair and class switch recombination through ATM and DNAPK-mediated γH2AX formation S Ramachandran, D Haddad, C Li, MX Le, AK Ling, CC So, RM Nepal, ... Cell reports 15 (7), 1554-1565, 2016 | 100 | 2016 |
Role of Caveolin‐1 in diabetes and its complications D Haddad, A Al Madhoun, R Nizam, F Al-Mulla Oxidative medicine and cellular longevity 2020 (1), 9761539, 2020 | 85 | 2020 |
SARS-CoV-2: Possible recombination and emergence of potentially more virulent strains D Haddad, SE John, A Mohammad, MM Hammad, P Hebbar, ... PloS one 16 (5), e0251368, 2021 | 64 | 2021 |
Generation and validation of intracellular ubiquitin variant inhibitors for USP7 and USP10 W Zhang, MA Sartori, T Makhnevych, KE Federowicz, X Dong, L Liu, ... Journal of molecular biology 429 (22), 3546-3560, 2017 | 54 | 2017 |
Dental pulp stem cells derived from adult human third molar tooth: a brief review A Al Madhoun, S Sindhu, D Haddad, M Atari, R Ahmad, F Al-Mulla Frontiers in Cell and Developmental Biology 9, 717624, 2021 | 41 | 2021 |
Genomic uracil homeostasis during normal B cell maturation and loss of this balance during B cell cancer development S Shalhout, D Haddad, A Sosin, TC Holland, A Al-Katib, A Martin, ... Molecular and cellular biology 34 (21), 4019-4032, 2014 | 38 | 2014 |
AID-expressing germinal center B cells cluster normally within lymph node follicles in the absence of FDC-M1+ CD35+ follicular dendritic cells but dissipate prematurely B Boulianne, MX Le, LA Ward, L Meng, D Haddad, C Li, A Martin, ... The Journal of Immunology 191 (9), 4521-4530, 2013 | 32 | 2013 |
ACE2 and FURIN variants are potential predictors of SARS-CoV-2 outcome: A time to implement precision medicine against COVID-19 F Al-Mulla, A Mohammad, A Al Madhoun, D Haddad, H Ali, ... Heliyon 7 (2), 2021 | 30 | 2021 |
A comprehensive germline variant and expression analyses of ACE2, TMPRSS2 and SARS-CoV-2 activator FURIN genes from the Middle East: Combating … F Al-Mulla, A Mohammad, A Al Madhoun, D Haddad, H Ali, ... BioRxiv, 2020.05. 16.099176, 2020 | 23 | 2020 |
AID and caspase 8 shape the germinal center response through apoptosis B Boulianne, OL Rojas, D Haddad, A Zaheen, A Kapelnikov, T Nguyen, ... The Journal of Immunology 191 (12), 5840-5847, 2013 | 20 | 2013 |
Inducible CTCF insulator delays the IgH 3′ regulatory region-mediated activation of germline promoters and alters class switching FZ Braikia, C Oudinet, D Haddad, Z Oruc, D Orlando, A Dauba, M Le Bert, ... Proceedings of the National Academy of Sciences 114 (23), 6092-6097, 2017 | 19 | 2017 |
Incidence of type 2 diabetes in Kuwaiti children and adolescents: results from the childhood-onset diabetes electronic registry (CODeR) H Al-Kandari, D Al-Abdulrazzaq, L Davidsson, P Sharma, A Al-Tararwa, ... Frontiers in endocrinology 10, 836, 2019 | 18 | 2019 |
Sense transcription through the S region is essential for immunoglobulin class switch recombination D Haddad, Z Oruc, N Puget, N Laviolette‐Malirat, M Philippe, C Carrion, ... The EMBO journal 30 (8), 1608-1620, 2011 | 18 | 2011 |
Increased plasma levels of adenylate cyclase 8 and cAMP are associated with obesity and type 2 diabetes: Results from a cross-sectional study SM Abdel-Halim, A Al Madhoun, R Nizam, M Melhem, P Cherian, ... Biology 9 (9), 244, 2020 | 16 | 2020 |
Kin17 facilitates multiple double-strand break repair pathways that govern B cell class switching MX Le, D Haddad, AK Ling, C Li, CC So, A Chopra, R Hu, JF Angulo, ... Scientific reports 6 (1), 37215, 2016 | 15 | 2016 |
Comparative proteomic analysis identifies EphA2 as a specific cell surface marker for Wharton’s jelly-derived mesenchymal stem cells A Al Madhoun, SK Marafie, D Haddad, M Melhem, M Abu-Farha, H Ali, ... International journal of molecular sciences 21 (17), 6437, 2020 | 14 | 2020 |
Wharton’s jelly mesenchymal stem cells: a concise review of their secretome and prospective clinical applications H Drobiova, S Sindhu, R Ahmad, D Haddad, F Al-Mulla, A Al Madhoun Frontiers in Cell and Developmental Biology 11, 1211217, 2023 | 13 | 2023 |
Microarray analysis reveals ONC201 mediated differential mechanisms of CHOP gene regulation in metastatic and nonmetastatic colorectal cancer cells A Al Madhoun, D Haddad, M Al Tarrah, S Jacob, W Al-Ali, R Nizam, ... Scientific reports 11 (1), 11893, 2021 | 8 | 2021 |
Duplication of a germline promoter downstream of the IgH 3′ regulatory region impairs class switch recombination JM Santos, FZ Braikia, C Oudinet, D Haddad, C Conte, A Dauba, ... Scientific reports 8 (1), 9164, 2018 | 7 | 2018 |
Adipose tissue caveolin-1 upregulation in obesity involves TNF-α/NF-κB mediated signaling A Al Madhoun, S Kochumon, D Haddad, R Thomas, R Nizam, L Miranda, ... Cells 12 (7), 1019, 2023 | 4 | 2023 |